Polyglyceryl-2 Isostearate: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: July 1, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Polyglyceryl-2 Isostearate?

Polyglyceryl-2 Isostearate is an ester formed when diglycerol, a short chain of two glycerin units, reacts with isostearic acid, a fatty acid usually sourced from plant oils such as rapeseed or coconut. The result is a waxy, oil loving material that mixes well with water when properly blended. Chemists began turning to this ingredient in the early 2000s while looking for alternatives to petroleum based or ethoxylated emulsifiers. Because it is made from renewable plant feedstocks and does not contain PEG, it fits neatly into the “clean beauty” and natural formulating movements.

The manufacturing process is straightforward: purified diglycerol is combined with isostearic acid in a controlled heat setting, encouraging the two molecules to join and form a stable ester. No solvents are needed, which helps keep the final material mild and low in impurities.

Its unique balance of water friendly and oil friendly parts makes Polyglyceryl-2 Isostearate a favorite in water in oil emulsions. You will often spot it on the ingredient list of liquid foundations, tinted moisturizers, BB creams, suncare products, cleansing balms, solid moisturizers, rich night creams and wash off masks where it helps keep the mix smooth and stable.

Polyglyceryl-2 Isostearate’s Cosmetic Benefits/Uses

In skin care and makeup formulas Polyglyceryl-2 Isostearate serves one clear, important role.

Emulsifying: It binds water and oil so they stay evenly blended throughout the jar or tube. This keeps creams from separating, gives foundations a silky gliding feel and allows high levels of nourishing oils to be included without leaving a greasy film.

Who Can Use Polyglyceryl-2 Isostearate

Polyglyceryl-2 Isostearate is considered gentle enough for most skin types including dry, normal, combination and oily. Its lightweight feel and non greasy finish make it comfortable even on easily congested or acne prone skin, while the added emolliency can soothe flakiness in drier complexions. Because it is not an active that alters skin function, there are no special concerns for sensitive skin beyond the usual need to watch for individual allergies.

The ingredient is plant derived so it suits both vegetarians and vegans. Manufacturers typically source the fatty acid from rapeseed or coconut and the glycerin backbone from vegetable oils, avoiding any animal inputs during processing.

Current safety data show no specific risks for women who are pregnant or breastfeeding when Polyglyceryl-2 Isostearate is used topically at normal cosmetic levels. This is not medical advice and anyone who is expecting or nursing should still clear new products with a healthcare professional to be certain they align with personal medical needs.

Polyglyceryl-2 Isostearate does not make skin more sensitive to sunlight, so there is no extra need for photo protection beyond the daily SPF already recommended for healthy skin.

Potential Side Effects/Adverse Reactions

Side effects from topical Polyglyceryl-2 Isostearate differ from person to person. The points below list potential reactions but most users will never encounter them when the ingredient is formulated and used as intended.

Mild skin irritation

Allergic contact dermatitis in those with a specific sensitivity to fatty acid esters

Temporary acne flare in very oily or acne prone skin if the overall formula is rich in comedogenic oils

Eye stinging or watering if a product containing the ingredient accidentally gets into the eyes

If any of these effects occur stop using the product and consult a qualified medical professional.

Comedogenic Rating

Polyglyceryl-2 Isostearate scores a 1 on the 0-5 comedogenic scale, meaning it is considered very unlikely to clog pores for most people. The branched structure of isostearic acid resists the dense packing that typically leads to pore blockage while the polyglycerin portion is water friendly and light. Together they create an emulsifier that does not sit heavily on skin or trap sebum. In practical terms this makes the ingredient generally suitable for acne-prone or breakout-prone skin, provided the rest of the formula is also low in comedogenic oils. One additional point: because it helps stabilize water-in-oil systems, it can appear in products that carry rich plant butters or silicones, so always consider the full ingredient list when assessing pore safety.

Summary

Polyglyceryl-2 Isostearate is mainly valued for its emulsifying power, letting water and oil mingle into smooth stable creams, balms and makeup while adding a hint of emolliency. It achieves this by pairing a water-loving polyglycerin backbone with an oil-loving isostearic tail, a structure that naturally positions itself at the water-oil boundary and locks the two phases together.

Although not as famous as long-standing emulsifiers like polysorbates or PEGs, it has gained steady popularity among formulators who want plant-derived clean label options that feel elegant and light. Consumers see it pop up most often in modern tinted bases, sunscreen sticks and rich yet non greasy moisturizers.

Current research and decades of safe use show Polyglyceryl-2 Isostearate to be low risk for irritation sensitization or photosensitivity when applied topically at cosmetic levels. Still, everyone’s skin is unique, so performing a small patch test with any new product containing this ingredient is a simple way to confirm personal compatibility.

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