Polyglyceryl-2 Sorbitan Tetraethylhexanoate: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: July 1, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Polyglyceryl-2 Sorbitan Tetraethylhexanoate?

Polyglyceryl-2 Sorbitan Tetraethylhexanoate is a plant-derived ingredient created by combining glycerin, sorbitol and 2-ethylhexanoic acid. Glycerin and sorbitol are sugars that come from crops such as corn or potatoes while 2-ethylhexanoic acid is often sourced from castor or other vegetable oils. Chemists link these building blocks through a series of heating and vacuum steps that remove water and form stable bonds, giving the final material a partly water-loving and partly oil-loving structure.

The cosmetic industry first explored this type of molecule in the late 1990s when brands needed gentler, more eco-friendly alternatives to older emulsifiers based on petroleum. Because it is biodegradable and made from renewable feedstocks it quickly found a place in natural and mainstream formulas alike.

You will spot Polyglyceryl-2 Sorbitan Tetraethylhexanoate in a wide range of leave-on and rinse-off products. Creams, lotions, sunscreens, cleansing oils, makeup removers, tinted moisturizers and sheet mask serums all use it to keep oil and water mixed. It is also popular in silicone-free foundations and anti-aging creams where a smooth light feel is important.

Polyglyceryl-2 Sorbitan Tetraethylhexanoate’s Cosmetic Benefits/Uses

This ingredient brings one main benefit to a formula.

As an emulsifying agent it helps oil and water blend into a stable, uniform mixture. This leads to creams and lotions that look smooth, spread evenly and stay mixed over time which improves texture, boosts the delivery of active ingredients and gives the final product a pleasant, non-greasy feel on the skin.

Who Can Use Polyglyceryl-2 Sorbitan Tetraethylhexanoate

This emulsifier is generally suitable for all skin types including dry, oily, combination and sensitive skin because it has a light non-occlusive texture and a mild profile that rarely disturbs the skin barrier.

People with acne-prone or congested skin usually tolerate it well since it is classified as low on the comedogenic scale and does not add heavy oils that might trap debris in pores.

The material is derived entirely from plant sources and no animal derivatives or by-products are involved in its production so it fits vegan and vegetarian lifestyles.

Available safety data shows no known reproductive or developmental concerns, meaning products containing this ingredient are considered low risk for those who are pregnant or breastfeeding. This is not medical advice and anyone who is expecting or nursing should still discuss any skincare routine with a doctor first to be safe.

Polyglyceryl-2 Sorbitan Tetraethylhexanoate is not known to increase photosensitivity so it does not make skin more prone to sunburn.

Potential Side Effects/Adverse Reactions

Responses to topical Polyglyceryl-2 Sorbitan Tetraethylhexanoate can vary from person to person. The points below outline potential side effects that might occur in rare cases. Most users will not experience these issues when the ingredient is used correctly in a well-formulated product.

  • Mild skin irritation such as redness or itching
  • Allergic contact dermatitis in individuals sensitive to sorbitan or fatty acid derivatives
  • Transient stinging if applied to broken or compromised skin
  • Eye irritation if the product accidentally gets into the eyes
  • Occasional surface breakouts in extremely oil-sensitive skin types if the rest of the formula is heavy

If you notice any discomfort swelling rash or prolonged redness stop using the product immediately and consult a healthcare professional.

Comedogenic Rating

Rating: 1 out of 5

This very low score is due to the ingredient’s large, branched structure which keeps it sitting on the surface and rinsing away easily rather than seeping into pores. It is also used at modest percentages and is free of heavy waxes or saturated fats that can clog skin.

Suitable for acne-prone or breakout-prone skin.

Formulas that combine it with rich butters or high levels of mineral oil may feel heavier overall so check the full ingredient list if you are extremely sensitive.

Summary

Polyglyceryl-2 Sorbitan Tetraethylhexanoate is primarily an emulsifier that marries oil and water so creams stay silky stable and easy to spread. Its partly water-loving and partly oil-loving segments line up at the interface of the two phases lowering surface tension and locking them together.

It shows up most often in clean beauty sunscreens lightweight lotions micellar cleansers and silicone-free makeup because it is plant based biodegradable and gives a soft non-greasy feel. While not as famous as older emulsifiers like polysorbate 20 its use is steadily growing among brands that want a greener label.

Current safety data finds it non toxic non sensitizing and low on the comedogenic scale which makes it a low risk pick for daily skin care. As with any new product though it is smart to perform a quick patch test to confirm personal compatibility.

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