Polyphenylsilsesquioxane/Trimethylsiloxysilicate: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: July 1, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Polyphenylsilsesquioxane/Trimethylsiloxysilicate?

Polyphenylsilsesquioxane/Trimethylsiloxysilicate is a silicone-based polymer made from silica, oxygen and small organic groups called phenyl and trimethylsilyl. These groups help the material form flexible yet durable films on the skin. Silicones entered the beauty world in the 1950s as chemists searched for lightweight ingredients that could protect skin and hair without feeling greasy. Over time, researchers blended different silicone units to fine-tune texture and staying power, which led to hybrids like this one.

The ingredient is created through a controlled condensation reaction where a silica source reacts with phenyl- and trimethyl-substituted silanes. The result is a three-dimensional network that ends in trimethylsiloxy groups, giving the polymer a smooth finish and good adhesion. After purification and drying, the powder or resin is ready to be mixed into cosmetic bases.

You will most often see Polyphenylsilsesquioxane/Trimethylsiloxysilicate in long-wear foundations, liquid lipsticks, waterproof mascaras, sunscreens, setting sprays and certain high-performance skin primers. Its main role is to lock the formula onto the skin or lashes so color, SPF or active ingredients last longer through sweat, oil and humidity.

Polyphenylsilsesquioxane/Trimethylsiloxysilicate’s Cosmetic Benefits/Uses

This ingredient is prized for its film forming ability. Once applied it creates an invisible, breathable layer that anchors pigments, UV filters or other actives to the skin or hair. The film resists water and oil so makeup stays put, sunscreen maintains its stated protection time, and hair products fight frizz and humidity. Because the film is flexible it moves with facial expressions and does not crack or flake, helping products feel comfortable during all-day wear.

Who Can Use Polyphenylsilsesquioxane/Trimethylsiloxysilicate

This film-forming silicone tends to sit weightlessly on the surface of skin so it suits most skin types including oily, combination, normal and dry. Those with very dehydrated or flaking skin may want to pair it with richer moisturizers because the ingredient itself is not hydrating. Extremely acne-prone users sometimes shy away from silicones in general but current data suggest this particular polymer has a very low clogging potential and rinses off cleanly with a good cleanser.

The ingredient is fully synthetic and contains no animal-derived materials so it is considered suitable for both vegans and vegetarians. As always check the full product label because companion ingredients such as beeswax, carmine or collagen could change a formula’s overall status.

Available safety assessments show minimal skin absorption and no hormone activity which means products containing Polyphenylsilsesquioxane/Trimethylsiloxysilicate are generally viewed as safe for women who are pregnant or breastfeeding. This is not medical advice and anyone who is expecting or nursing should run their skincare routine past a qualified healthcare provider to be certain it meets individual needs.

The polymer does not make skin more sensitive to sunlight and can actually help stabilize UV filters in sunscreens. It also plays nicely with most other cosmetic actives so there are no special layering rules to follow.

Potential Side Effects/Adverse Reactions

Reactions to topical Polyphenylsilsesquioxane/Trimethylsiloxysilicate vary from person to person. The following is a list of potential side effects, though most users will not experience any issues when the ingredient has been formulated correctly.

  • Mild skin irritation or redness in very sensitive individuals
  • Transient clogged pores if layered heavily with other occlusives on acne-prone skin
  • Eye irritation or watering if the ingredient migrates into the eyes from mascara or setting spray
  • Rare contact allergy leading to itching or rash

If you notice any of these effects stop using the product and consult a healthcare professional for guidance.

Comedogenic Rating

1/5. Polyphenylsilsesquioxane/Trimethylsiloxysilicate has a large molecular structure that sits on the surface and is easily removed with cleanser, so it rarely blocks pores. Most users prone to acne can use it without triggering breakouts, especially when the rest of the formula is lightweight. In very heavy or layered products it could increase the chance of congestion but the risk remains low.

Because the polymer resists oil and water it may actually help keep excess sebum from mixing with makeup which can further reduce the likelihood of clogged pores.

Summary

Polyphenylsilsesquioxane/Trimethylsiloxysilicate is mainly a film former that keeps pigments, SPF and styling agents locked in place while remaining flexible and comfortable. The three dimensional silicone network creates an invisible shield that repels sweat and oil, giving long wear cosmetics their staying power.

It pops up in many modern long wear foundations, liquid lipsticks, waterproof mascaras and sunscreens, though it is not as famous as silicones like dimethicone. Formulators value it for its performance so its presence is growing in both prestige and drugstore lines.

Toxicology reviews show minimal absorption, no hormone disruption and a very low irritation profile which makes it a safe choice for most people. Still, everyone’s skin is unique so it is smart to patch test any new product that contains this ingredient before diving into full face or body use.

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