Polyquaternium-19: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: July 1, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Polyquaternium-19?

Polyquaternium-19 is a man-made conditioning polymer created by reacting ethanol with aminomethyloxirane, then linking those small units into a long chain. The result is a positively charged molecule that naturally clings to hair and skin, forming a lightweight coating. First developed in the late 1980s as chemists searched for gentler alternatives to heavy silicones, it quickly found a home in hair care labs because of its smooth feel and humidity resistance.

Manufacturing starts with refined petrochemical feedstocks that are purified, reacted under controlled heat and pressure, then neutralized and filtered. The finished liquid is clear to pale yellow and water-soluble, making it easy to blend into standard cosmetic bases.

You will most often spot Polyquaternium-19 in shampoos, rinse-out and leave-in conditioners, curl creams, styling gels, anti-frizz serums, hair masks, detangling sprays and sometimes in skin-care gels or sheet mask essences where a flexible film is desired.

Polyquaternium-19’s Cosmetic Benefits/Uses

This ingredient adds multiple performance benefits to modern formulas

  • Antistatic: The positive charge neutralizes static electricity on hair strands which helps reduce flyaways, eases combing and keeps styles smoother in dry weather
  • Film forming: It creates a thin breathable layer that locks in moisture, boosts shine and gives hair or skin a soft silky finish while guarding against environmental stress

Who Can Use Polyquaternium-19

Because Polyquaternium-19 is water based, lightweight and non greasy it sits well on all skin and hair types, from oily to very dry. Sensitive skin usually tolerates it because the polymer stays on the surface instead of soaking in, though those with a history of allergy to quats may want to proceed with extra care.

The ingredient is synthesized entirely from petrochemical feedstocks with no animal by-products, so it is suitable for both vegans and vegetarians.

No data suggest that Polyquaternium-19 is harmful to pregnant or breastfeeding women when used topically in standard cosmetic amounts. This is not medical advice and anyone who is pregnant or nursing should have a doctor review their routine just to be safe.

The polymer does not make skin more sensitive to sunlight and it has no known conflicts with common actives such as retinol or acids. It can, however, reduce the foaming power of some sulfate-free shampoos if added at very high levels, something formulators already account for.

Potential Side Effects/Adverse Reactions

Reactions to topical Polyquaternium-19 vary from person to person. The points below list potential side effects, but most users will not run into these issues when the ingredient is used at normal cosmetic levels.

  • Mild skin or scalp irritation
  • Allergic contact dermatitis in individuals sensitive to quaternary ammonium compounds
  • Eye irritation if the raw liquid splashes directly into eyes
  • Product buildup on hair leading to dullness if not cleansed thoroughly over time

If any discomfort, redness or itching develops stop using the product and consult a healthcare professional or dermatologist.

Comedogenic Rating

Rating: 0 out of 5. Polyquaternium-19 is a large water-soluble polymer that sits on the surface of skin and hair, then rinses away easily. It does not contain oily or waxy components that typically block pores, so it is considered non-comedogenic.

Suitable for acne-prone or breakout-prone skin.

Because it is cationic, the polymer may bind to dead skin cells and other residues, so a thorough cleanse at the end of the day is helpful to keep skin feeling fresh.

Summary

Polyquaternium-19 works primarily as an antistatic and film-forming agent. Its positive charge neutralizes static on hair, reducing flyaways while its flexible film locks in moisture and adds shine. On skin the same film leaves a light, smooth finish and helps retain hydration.

Used most often in shampoos, conditioners and styling products, it is less famous than silicones but has a steady following among formulators who want lightweight conditioning without greasiness.

Current research and decades of cosmetic use point to a very low risk profile when applied at standard concentrations. Still, everyone’s skin is unique, so perform a simple patch test whenever trying a new product that contains Polyquaternium-19.

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