What Is Polyquaternium-63?
Polyquaternium-63 is a synthetic polymer that belongs to the large family of cationic, or positively charged, conditioning agents known as polyquaterniums. Chemically, it is the quaternary ammonium salt created by polymerizing acrylamide, acrylic acid and ethyltrimonium chloride acrylate. The positive charge of the finished polymer allows it to cling to the slightly negative surface of hair and skin, which is the secret behind its conditioning power.
The broader polyquaternium category emerged in the 1970s when formulators were searching for ingredients that could smooth damaged hair without leaving heavy buildup. Polyquaternium-63 was developed as a newer option that offers strong conditioning at low use levels while remaining water soluble, making it easy to rinse away.
Production involves a controlled, water based free radical polymerization of its three monomers followed by filtration and neutralization to ensure purity and safety for cosmetic use. Because it is made in a lab, supply is consistent and free from the variability that can affect plant derived materials.
Polyquaternium-63 is most often found in rinse off and leave in hair products such as shampoos, conditioners, masks, anti frizz creams, detangling sprays and styling gels. In skin care, it shows up in light lotions, after shave balms and hydrating serums where a silky, non greasy finish is desired.
Polyquaternium-63’s Cosmetic Benefits/Uses
This ingredient earns its keep by delivering targeted conditioning benefits in both hair and skin formulas.
- Hair conditioning – The positive charge of Polyquaternium-63 binds to the cuticle, smoothing rough spots, reducing static and making strands feel softer and easier to comb. It can also boost shine and help protect against breakage from brushing or heat styling.
- Skin conditioning – When used in lotions or serums, it forms a light, invisible film that leaves skin feeling silky and hydrated without a heavy or oily residue. This film can also help reduce moisture loss over time, supporting a smoother appearance.
Who Can Use Polyquaternium-63
Polyquaternium-63 is generally considered friendly for all skin types. Its lightweight film makes it a welcome addition for dry skin that needs extra moisture retention and for oily or combination skin that prefers non-greasy hydration. Sensitive skin usually tolerates it because the polymer’s large molecular size keeps it on the surface instead of penetrating deeply, though individuals with a known sensitivity to quaternary ammonium compounds should stay cautious.
The ingredient is fully synthetic, so it contains no animal-derived materials. That means it is suitable for both vegetarians and vegans, provided the finished product has not been tested on animals according to personal ethical standards.
No data suggest that topical use poses a risk to pregnant or breastfeeding women when applied as directed in cosmetics. Still, this is not medical advice and anyone who is pregnant or nursing should discuss new skincare or haircare products with a healthcare professional first.
Polyquaternium-63 is not known to increase photosensitivity. Users do not need to adjust their normal sun protection habits solely because a product contains this ingredient.
Potential Side Effects/Adverse Reactions
Reactions to any cosmetic ingredient can vary from person to person. The following points outline possible but uncommon side effects linked to the topical use of Polyquaternium-63 when it is used at typical levels in properly formulated products.
- Mild skin redness or irritation in individuals who are sensitive to cationic polymers
- Eye irritation if a concentrated product accidentally gets into the eyes during application or rinsing
- Build-up or weighed-down feel on very fine hair if used in high concentrations in leave-in formulas
If you experience any discomfort or unexpected reaction while using a product that contains Polyquaternium-63 stop using it and consult a healthcare professional.
Comedogenic Rating
Rating: 1 / 5
Polyquaternium-63 is a large, water-soluble polymer that tends to stay on the surface of skin rather than sinking into pores. Because it creates a breathable, lightweight film and rinses away easily, it is very unlikely to trap sebum or dead skin cells that could lead to clogged pores. For that reason most formulators view it as essentially non-comedogenic, with only a minimal risk in very heavy leave-on products.
In practical terms this ingredient is generally fine for people prone to acne or breakouts.
If a product pairs Polyquaternium-63 with heavier oils or waxes their combined texture, not the polymer itself, could raise the pore-clogging potential so the overall formula still matters.
Summary
Polyquaternium-63 conditions hair and skin by laying down a thin, positively charged film that smooths cuticles, tames static and helps skin retain moisture without greasiness. It delivers noticeable softness at low use levels and rinses clean, which is why chemists like it for both wash-off and leave-on products.
While it is not a household name it enjoys steady use in modern shampoos, conditioners and lightweight lotions because it offers silicone-like slip without heavy buildup.
The available safety data show a very low risk profile with rare reports of mild irritation in sensitive users. As with any new cosmetic it is wise to patch test a product containing Polyquaternium-63 before full use to make sure your skin plays nicely with the formula.