Polyurea Crosspolymer-6: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: July 1, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Polyurea Crosspolymer-6?

Polyurea Crosspolymer-6 is a synthetic polymer created by reacting 1,3-propanediol 2-ethyl-2-(hydroxymethyl)- with bis(isocyanatomethyl)benzene, producing a highly cross-linked polyurea network. Both starting materials come from refined petrochemical sources, giving formulators tight control over purity and performance. The ingredient first appeared in cosmetics in the early 2010s when manufacturers were looking for lightweight powders that could blur skin texture without the dryness often linked to traditional silica or talc. By adjusting reaction time, temperature and catalyst levels, chemists create hollow or solid micro-spheres that are then filtered, washed and milled into an ultra-fine powder ready for skin-care and makeup use.

You will most often spot Polyurea Crosspolymer-6 in face primers, liquid and powder foundations, sunscreens, tinted moisturizers, sheet or rinse-off masks, anti-aging serums and certain long-wear eye or lip products. Its popularity stems from the way it improves product feel, finish and staying power while adding minimal weight.

Polyurea Crosspolymer-6’s Cosmetic Benefits/Uses

This ingredient serves one main purpose in formulas: it is a film former. Once applied, it lays down a thin flexible layer that anchors pigments, active ingredients and moisturizing agents to the skin. The film helps products resist sweat and sebum, smooths the look of pores and fine lines, locks in hydration and extends wear time so makeup stays fresh for longer.

Who Can Use Polyurea Crosspolymer-6

Because it is an inert film-forming powder with no oil or fragrance, Polyurea Crosspolymer-6 is generally suitable for all skin types including oily, dry, combination and sensitive skin. It has a lightweight texture that does not noticeably clog pores, making it acceptable for those prone to breakouts. Extremely dry or eczema-prone skin may prefer formulations that pair the polymer with richer emollients because the film it forms can feel too lightweight on its own.

The ingredient is synthesized entirely from petrochemical sources and contains no animal-derived inputs so it is appropriate for vegans and vegetarians.

No data suggest that Polyurea Crosspolymer-6 poses special concerns for pregnant or breastfeeding women when used topically in cosmetics. This is not medical advice and anyone who is pregnant or nursing should discuss all skincare products with a qualified healthcare provider.

The polymer is not known to cause photosensitivity and it does not make skin more vulnerable to the sun. As with any cosmetic ingredient you should still apply a broad-spectrum sunscreen as part of a normal daytime routine.

Potential Side Effects/Adverse Reactions

Individual responses vary and the following list covers potential but uncommon reactions. When the ingredient is used at typical cosmetic concentrations most people experience none of these issues.

  • Mild skin irritation such as redness or stinging
  • Contact dermatitis in users allergic to residual isocyanate traces
  • Transient clogged pores or small whiteheads in very acne-prone skin when used in heavy, occlusive formulas
  • Eye irritation if loose powder accidentally gets into the eyes during application

If irritation or any other negative reaction occurs stop using the product immediately and consult a healthcare professional if symptoms persist.

Comedogenic Rating

Rating: 1 / 5. Polyurea Crosspolymer-6 is a lightweight, inert powder that creates a breathable film rather than an oily or waxy layer, so it rarely blocks pores on its own. It does not contain fatty acids or heavy emollients that typically trigger breakouts, earning it a low score. The rating is not a perfect 0 because any film former can trap existing sebum or debris if used in very rich formulas or applied in thick layers. Overall it is considered suitable for acne-prone skin when used in well-balanced products. Users who struggle with severe congestion may still prefer lighter routines.

Worth noting: the particle size is too large to penetrate follicles, which further limits direct pore-clogging potential. Formula partners such as heavy oils have a bigger influence on comedogenicity than the polymer itself.

Summary

Polyurea Crosspolymer-6 is a synthetic film former that lays down a flexible veil on the skin to anchor pigments, actives and moisture. By doing so it boosts wear time, blurs texture and helps products resist sweat and sebum without feeling heavy. Its popularity has grown steadily since the early 2010s thanks to the clean, soft finish it provides in primers, foundations and sunscreens. While not a household name, it has become a quiet workhorse ingredient for formulators looking to replace talc or silica.

Current safety data show a low risk of irritation, allergy or pore clogging at the small percentages used in cosmetics. As with any new skincare ingredient it is wise to patch test a product first to make sure your skin agrees with it.

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