What Is Potato Sh-Polypeptide-1?
Potato Sh-Polypeptide-1 is a lab produced protein fragment originally encoded by a gene found in potatoes. Scientists insert this potato gene into a harmless host cell, often a cultured plant or yeast, which then manufactures the peptide in large amounts. After fermentation the peptide is filtered, purified and blended into a stable powder or liquid that cosmetic chemists can add to formulas.
The idea of turning plant genes into skincare actives began gaining ground in the early 2000s when transgenic technology became more precise. Developers noticed that certain plant derived peptides could form a light protecting film on skin, so they began testing potato based sequences for this purpose. Today the ingredient shows up in modern K-beauty lines and boutique Western brands that focus on gentle barrier care.
You will most often see Potato Sh-Polypeptide-1 in leave-on products where a thin, consistent layer makes the biggest difference. Look for it in daily moisturizers, lightweight serums, soothing after-sun gels, sheet masks and overnight creams that promise to strengthen the skin barrier.
Potato Sh-Polypeptide-1’s Cosmetic Benefits/Uses
This peptide is included in formulas because it serves one clear role that supports skin health.
Skin protecting: It forms a breathable film that helps limit water loss and shields against everyday irritants like pollution particles and harsh cleansers. By reinforcing the surface, it can leave skin feeling calmer, more resilient and better hydrated throughout the day.
Who Can Use Potato Sh-Polypeptide-1
Potato Sh-Polypeptide-1 is considered gentle enough for all skin types including dry, balanced, oily and mature skin. Its lightweight film-forming nature makes it especially helpful for those with a compromised barrier or dehydration. People with extremely sensitive or allergy-prone skin may still want to pay extra attention to the full ingredient list of a product, as reactions are possible with any cosmetic peptide.
The peptide is produced in a fermentation tank using plant or yeast cells so no animal-derived materials are involved. This makes it a vegan and vegetarian friendly choice.
Current research does not show any specific concerns for women who are pregnant or breastfeeding when the ingredient is applied topically. Still, this text is not medical advice and anyone who is expecting or nursing should confirm product choices with a qualified healthcare provider.
Potato Sh-Polypeptide-1 is not known to increase photosensitivity. Daily sunscreen is still recommended for overall skin health but there is no extra sun caution tied directly to this ingredient.
Potential Side Effects/Adverse Reactions
Side effects and reactions to the topical application of Potato Sh-Polypeptide-1 can vary from person to person. The points below describe potential issues yet most users will not experience them if the ingredient has been correctly formulated and preserved.
- Mild redness or stinging on application
- Itching or tightness as the film forms
- Localized rash or hives in individuals with potato protein allergy
- Contact dermatitis triggered by other formula components rather than the peptide itself
- Reduced efficacy of the peptide if layered directly under very acidic products which can break down the protein structure
If any of these effects occur stop using the product and seek advice from a healthcare professional or dermatologist.
Comedogenic Rating
Rating: 0–1. Potato Sh-Polypeptide-1 is a water soluble peptide free of heavy oils, waxes or fatty acids that commonly block pores. It forms a light breathable film then rinses away easily so it is very unlikely to trap sebum or debris.
This low score means the ingredient is generally well suited for people prone to acne or breakouts.
Keep in mind the overall pore clogging risk depends on the full formula. If the peptide is blended with rich butters or thick silicones the product could still feel heavy on blemish prone skin.
Summary
Potato Sh-Polypeptide-1 is a vegan friendly peptide that strengthens the skin barrier by laying down a thin protective film helping skin stay hydrated and shielded from everyday irritants. This barrier support is its primary function and it accomplishes it without adding grease or weight.
Although not yet a mainstream superstar it shows up in select K-beauty lines and niche western serums focused on gentle barrier care and is slowly gaining traction with formulators seeking plant based actives.
Topical use is considered safe with a very low chance of irritation or pore clogging when formulated correctly yet every complexion is unique so perform a quick patch test when trying any new product that features this peptide.