Pyridoxine Dicaprylate: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: July 1, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Pyridoxine Dicaprylate?

Pyridoxine dicaprylate is a lab made ester that comes from pyridoxine, a form of vitamin B6, and caprylic acid, a fatty acid taken from coconut or palm oil. By linking two caprylate groups to the vitamin core chemists create an oil loving molecule that blends smoothly into creams and lotions. This tweak keeps the nourishing traits of vitamin B6 but makes the ingredient more stable and easier for skin and hair to accept.

The cosmetic world began looking at vitamin B6 derivatives in the late 1990s when brands searched for gentler options to soothe dryness and static. Pyridoxine dicaprylate stood out because it could do double duty on both skin and hair. Today it is made through a straightforward esterification process: purified pyridoxine is reacted with caprylic acid in the presence of a catalyst then filtered and refined until it reaches cosmetic grade purity.

You will spot it on the ingredient list of lightweight facial moisturizers, anti aging serums, soothing sheet masks, leave in conditioners, anti frizz sprays, color care shampoos and nourishing hair masks. Formulators like it because it stays clear, blends easily with oils and emulsifiers and holds up well in a wide pH range.

Pyridoxine Dicaprylate’s Cosmetic Benefits/Uses

Here is how this multitasker can improve a beauty product

  • Antistatic – Helps reduce the electrical charge that makes hair fly away or cling to brushes so strands stay smooth and easier to style
  • Hair Conditioning – Softens and coats the hair shaft which boosts shine improves slip during combing and guards against breakage
  • Skin Conditioning – Adds a light layer of moisture that leaves skin feeling supple and comfortable without a greasy finish

Who Can Use Pyridoxine Dicaprylate

Pyridoxine dicaprylate is generally gentle enough for all skin types including dry, normal, combination and oily. Its light emollient feel offers moisture without heaviness which keeps pores from feeling clogged, so even acne-prone users usually tolerate it. Sensitive skin tends to get along with this ingredient because it is non acidic and has a low irritation profile. People with a diagnosed allergy to vitamin B6 or coconut-derived caprylic acid should avoid it.

The molecule is synthesized from plant-based raw materials and involves no animal by-products or animal testing requirements, so it suits both vegetarians and vegans. Still, always check the rest of the formula because other ingredients in the finished product might not be vegan friendly.

No data suggests a risk for pregnant or breastfeeding women when the ingredient is applied topically and in the small amounts found in cosmetics. Absorption through intact skin is minimal, yet this is not medical advice and anyone who is pregnant or nursing should confirm product choices with a healthcare professional.

Pyridoxine dicaprylate is not known to cause photosensitivity and does not increase the need for extra sun protection beyond your usual SPF routine.

Potential Side Effects/Adverse Reactions

Reactions to topical pyridoxine dicaprylate differ from person to person. The issues listed below are possible but uncommon when the ingredient is properly formulated and used as directed.

  • Mild skin irritation – temporary redness or stinging, most often in very sensitive skin
  • Contact dermatitis – rare allergic response presenting as itching or rash in people sensitized to vitamin B6 derivatives
  • Eye irritation – watering or burning if the product accidentally gets into the eyes
  • Scalp build-up – waxy feel or dullness if a heavy leave-in formula is applied too often without thorough cleansing

If you notice any discomfort or unusual reaction stop using the product and consult a healthcare professional

Comedogenic Rating

Rating: 1 / 5. Pyridoxine dicaprylate is a lightweight ester that sinks in quickly and leaves little oily residue so it has a very low chance of blocking pores. It is mostly used at modest levels which keeps the formula from feeling heavy. For these reasons it is generally suitable for people who are prone to acne or breakouts. Formulas that pair it with heavy waxes or butters could raise the overall comedogenic potential so always look at the full ingredient list.

Summary

Pyridoxine dicaprylate conditions skin and hair, tames static and adds a soft touch of moisture. It does this by teaming the water friendly benefits of vitamin B6 with caprylic acid which lets the molecule blend into oils and coat surfaces evenly. The ingredient shows up in a fair number of modern moisturizers, sheet masks and anti frizz sprays but it is still more of a supporting act than a headline star.

Current safety data points to a low risk of irritation or pore clogging for most users. Even so every skin is different so do a quick patch test when you try a new product that contains it just to be sure your skin stays happy.

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