Pyridoxine Dilaurate: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: July 1, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Pyridoxine Dilaurate?

Pyridoxine Dilaurate is a lab-crafted ester formed when vitamin B6 (pyridoxine) is chemically linked with two molecules of lauric acid, a fatty acid most commonly obtained from coconut or palm kernel oil. The result is a silky, oil-compatible powder that blends smoothly into creams and lotions. The ingredient first appeared in cosmetic research in the late 1990s as chemists searched for vitamin derivatives that could survive better in formulations than plain water-soluble B-vitamins. By attaching lauric acid, they made pyridoxine more stable in oils and emulsions and easier to disperse across skin and hair.

Manufacturing starts with purified pyridoxine hydrochloride. Through an esterification step, lauric acid is activated then reacted with pyridoxine under controlled heat and vacuum. The finished ester is filtered, washed, and milled into a fine powder ready for cosmetic use.

You will most often see Pyridoxine Dilaurate in leave-on conditioners, anti-frizz serums, moisturizing hair masks, skin creams aimed at dryness, after-sun lotions, and multitasking face moisturizers that promise both hydration and a soft finish.

Pyridoxine Dilaurate’s Cosmetic Benefits/Uses

Pyridoxine Dilaurate plays several helpful roles when added to skin or hair care formulas

  • Antistatic – Helps neutralize the static charge that makes hair flyaway or cling to clothing so strands stay smoother and easier to style
  • Hair conditioning – Forms a light film on the surface of hair fibers which improves slip, reduces tangles, and leaves hair feeling softer and looking shinier
  • Humectant – Attracts and binds water from the environment into the product and onto the skin or hair helping to maintain moisture levels through the day
  • Skin conditioning – Softens and smooths the skin surface while supporting a comfortable, hydrated feel making creams infused with the ingredient more pleasant to apply

Who Can Use Pyridoxine Dilaurate

Pyridoxine Dilaurate is generally well tolerated by all skin types including dry, normal, combination and oily since it offers lightweight moisture without a greasy feel. Sensitive skin usually gets along with it too because the esterified form of vitamin B6 is less reactive than the pure vitamin. Those with very oily or acne-prone skin may want to monitor how their complexion responds as any fatty acid derivative has a small chance of feeling too rich for some pores.

The ingredient is considered suitable for vegans and vegetarians. Lauric acid used in cosmetics is almost always sourced from coconut or palm kernel oil, not animal fats, and the rest of the synthesis involves plant-derived or petrochemical intermediates.

No specific contraindications exist for pregnant or breastfeeding women, but this is not medical advice. Expectant or nursing mothers should show any product containing Pyridoxine Dilaurate to their healthcare provider before adding it to a routine, just to be safe.

Pyridoxine Dilaurate does not make skin more sensitive to sunlight, so there is no added risk of photosensitivity. It plays well with common actives like niacinamide, hyaluronic acid and low-level exfoliating acids, and it remains stable across the usual cosmetic pH range.

Potential Side Effects/Adverse Reactions

Responses to topical Pyridoxine Dilaurate can vary from person to person. The points below outline potential side effects, though they are not expected for most users when the ingredient is properly formulated and used as directed.

  • Mild skin irritation such as redness or itching
  • Contact dermatitis in individuals allergic to vitamin B6 derivatives or lauric acid
  • Temporary stinging if applied to broken or freshly exfoliated skin
  • Rare clogging of pores or small breakouts in very oily skin types
  • Eye irritation if the product accidentally gets into the eyes

If any uncomfortable reaction occurs stop using the product and seek advice from a qualified healthcare professional.

Comedogenic Rating

Rating: 2 out of 5. While lauric acid on its own has a reputation for clogging pores, esterifying it with pyridoxine changes the molecule’s size and behavior so it sits on the skin without penetrating as deeply. Most formulas include Pyridoxine Dilaurate at low levels, further lowering its pore-blocking potential.

Suitable for acne-prone or breakout-prone skin in most cases, but very oily complexions may still prefer lighter alternatives.

Because it is oil-compatible, the overall comedogenicity of a finished product will also depend on the other emollients and occlusives in the formula.

Summary

Pyridoxine Dilaurate conditions skin and hair, attracts water as a humectant, reduces static and forms a soft film that boosts smoothness. The lauric acid tails anchor it to the surface while the vitamin B6 core helps hold moisture, so a small amount delivers a noticeable silky finish.

It is not a headline ingredient in most mainstream lines, showing up mainly in specialized leave-on conditioners or mid-tier moisturizers rather than household-name products, yet formulators who work with it appreciate its stability in both oil-rich and emulsion systems.

Overall safety is high with only rare reports of irritation or pore clogging. As with any new skincare addition perform a short patch test first to ensure personal compatibility.

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