Quaternium-79 Hydrolyzed Silk: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 30, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Quaternium-79 Hydrolyzed Silk?

Quaternium-79 Hydrolyzed Silk is a modified silk protein created by breaking natural silk fibers into smaller, water-friendly pieces and then adding a gentle positive charge to them. The silk itself comes from silkworm cocoons. Chemists hydrolyze the long silk strands into shorter chains so they dissolve in water, then react them with quaternary ammonium compounds so the final material can cling to hair and skin, which naturally carry a slight negative charge. This positive charge is why the ingredient begins with “Quaternium.”

Silk has been prized in beauty rituals for centuries thanks to its smooth feel. In the late 20th century scientists learned how to hydrolyze and quaternize silk peptides, giving rise to ingredients like Quaternium-79 Hydrolyzed Silk that disperse well in modern water-based formulas. The process typically involves enzymatic or acid hydrolysis of silk fibroin, purification, then a controlled reaction with fatty acid chlorides that carry the quaternary ammonium group.

You will most often see Quaternium-79 Hydrolyzed Silk in rinse-off and leave-on hair products such as shampoos, conditioners, masks, serums and styling sprays where it helps tame static and boost softness. It also appears in skin care lines including daily moisturizers, anti-aging creams, after-sun gels and hand lotions to add a silky finish and light conditioning.

Quaternium-79 Hydrolyzed Silk’s Cosmetic Benefits/Uses

This multitasking ingredient offers several perks when blended into beauty formulas

  • Antistatic: The positive charge neutralizes static electricity on hair strands so flyaways are reduced and styles stay smooth even in dry weather
  • Hair conditioning: The silk peptides form a lightweight film over the hair cuticle, improving slip, easing detangling and adding a soft touch without heavy buildup
  • Skin conditioning: On skin the same film-forming action boosts surface hydration, leaves a velvety feel and can make lotions spread more evenly for a refined finish

Who Can Use Quaternium-79 Hydrolyzed Silk

Quaternium-79 Hydrolyzed Silk is generally well tolerated by most skin types. Dry or mature skin may appreciate its light conditioning film while normal and combination skin usually find it comfortable. Oily or very acne-prone skin can still use it because the ingredient is lightweight but those concerned about buildup may prefer lower concentrations or rinse-off products.

The material comes from silkworm cocoons so it is not suitable for vegans or strict vegetarians who avoid animal-derived ingredients. Consumers following those lifestyles may want to choose plant-based protein alternatives instead.

No published data link this ingredient to issues during pregnancy or breastfeeding. It does not penetrate deeply or act on hormones so topical use is considered low risk, yet this is not medical advice and anyone who is pregnant or nursing should review all cosmetic products with a doctor to be safe.

Quaternium-79 Hydrolyzed Silk does not increase photosensitivity so there is no special sun-care concern beyond the normal daily use of sunscreen.

Potential Side Effects/Adverse Reactions

Reactions to topical Quaternium-79 Hydrolyzed Silk vary from person to person. The effects listed below are only potential outcomes and are unlikely for the average user when the product is formulated correctly.

  • Mild skin irritation in sensitive individuals, especially if used in high concentrations
  • Contact allergy in people who are allergic to silk proteins or quaternary ammonium compounds
  • Eye irritation if the product accidentally gets into the eyes during application or rinsing
  • Hair buildup leading to limp or weighed-down strands when very heavy leave-in products are layered repeatedly

If any discomfort or adverse reaction occurs stop using the product and seek guidance from a healthcare professional.

Comedogenic Rating

Rating: 1 / 5

Quaternium-79 Hydrolyzed Silk is water soluble and forms an ultrathin breathable film rather than an oily layer that blocks pores. Although the molecule carries a few fatty side chains, they are tightly bound to the protein and rinse off easily. This keeps the pore-clogging potential very low.

With a score of 1 it is generally suitable for people prone to acne or breakouts, especially when used in lightweight leave-in or rinse-off formulas.

Only heavy layering without proper cleansing might let residue build up and trap debris, so balanced cleansing is still wise.

Summary

Quaternium-79 Hydrolyzed Silk delivers antistatic, hair conditioning and skin conditioning benefits by using its positive charge to anchor silk peptides to the negatively charged surface of hair and skin. Once in place it creates a microfilm that boosts slip, smooths cuticles and helps skin hold moisture for a velvety finish.

The ingredient is moderately popular, seen in salon shampoos, styling sprays, luxe lotions and a growing number of mid-range products, though its animal origin and higher cost keep it from being as widespread as plant proteins or silicones.

Current research and decades of use point to a low risk of irritation or other issues. Still, every skin is unique, so it is sensible to patch test any new product containing this ingredient before full-on use.

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