Rice Sh-Polypeptide-9 Dimer: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 30, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Rice Sh-Polypeptide-9 Dimer?

Rice Sh-Polypeptide-9 Dimer is a skin care ingredient derived from rice proteins. It is formed when two identical Rice Sh-Polypeptide-9 molecules are linked together by a natural sulfur bridge, creating a stable homodimer. The result is a water-soluble peptide complex that easily blends into creams, gels and serums.

Peptides from grains have been explored since the late 1990s for their ability to mimic skin’s own building blocks. Researchers isolated short sequences from rice, noticed their skin-softening effect and later discovered that pairing the peptides into a dimer made them more resilient in cosmetic formulas. Today the ingredient is produced through controlled enzymatic hydrolysis of rice proteins, followed by purification and a gentle oxidation step that connects the two peptide chains.

You will spot Rice Sh-Polypeptide-9 Dimer in lightweight moisturizers, hydrating masks, anti-aging serums and leave-on treatments aimed at boosting skin smoothness and suppleness. Its mild nature makes it suitable for daily use across many product formats.

Rice Sh-Polypeptide-9 Dimer’s Cosmetic Benefits/Uses

When added to a topical formula Rice Sh-Polypeptide-9 Dimer delivers two key benefits:

  • Humectant – attracts and holds water on the skin surface helping to maintain hydration, reduce tightness and give a plump, fresh look
  • Skin conditioning – improves the feel of the skin by smoothing texture, supporting a softer touch and enhancing overall comfort after application

Who Can Use Rice Sh-Polypeptide-9 Dimer

Rice Sh-Polypeptide-9 Dimer is gentle enough for most skin types. Dry and dehydrated complexions appreciate its humectant action while oily and combination skin enjoy lightweight hydration that will not feel greasy. Sensitive skin tends to tolerate the peptide well because it is free of common irritants, though anyone with a rare allergy to rice proteins should proceed with caution.

The ingredient is completely plant based and produced without animal derivatives, making it suitable for both vegans and vegetarians.

Current safety data show no concerns for women who are pregnant or breastfeeding when this peptide is used topically in normal cosmetic concentrations. This is not medical advice and anyone who is pregnant or nursing should always clear new skincare products with a qualified health professional.

Rice Sh-Polypeptide-9 Dimer does not increase photosensitivity so there is no extra need for sun avoidance beyond standard daily SPF use.

Potential Side Effects/Adverse Reactions

Side effects and reactions to topical Rice Sh-Polypeptide-9 Dimer can vary from person to person. The points below outline potential issues only; most users will not experience negative effects when the ingredient has been formulated and used correctly.

  • Mild redness or warmth
  • Temporary itching or tingling, especially on freshly exfoliated or broken skin
  • Allergic contact dermatitis in individuals with a rice or grain protein allergy
  • Rare clogged pores in very oily skin if the finished formula is overly occlusive

If any irritation, swelling or persistent discomfort occurs stop use immediately and seek advice from a healthcare professional or dermatologist.

Comedogenic Rating

Comedogenic rating: 0/5 (non-comedogenic). Rice Sh-Polypeptide-9 Dimer is a small water soluble peptide that does not form an occlusive film or leave excess oil on the surface so it is highly unlikely to block pores. Its hydrating action comes from attracting water not from heavy emollients that can trap sebum. The finished product formula always plays a role but the peptide itself carries no pore clogging risk.

Suitable for acne prone or breakout prone skin.

If the peptide is blended into a very rich cream with waxes or butters the overall product could still feel heavy so always consider the full ingredient list.

Summary

Rice Sh-Polypeptide-9 Dimer functions mainly as a humectant and skin conditioning agent. The paired peptide structure binds water to the skin then helps hold it there which supports a smoother softer feel.

It is not yet as famous as hyaluronic acid but interest is growing among brands seeking vegan grain sourced actives. You will spot it most often in lightweight moisturizers masks and anti-aging serums.

Available safety data shows a very low risk of irritation or sensitization making it suitable for regular use. Still, it is wise to patch test any new product containing this peptide to confirm personal compatibility.

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