What Is Sh-Oligopeptide-90 Sp?
Sh-Oligopeptide-90 Sp is a lab-made fragment of keratin-associated protein 1-1, a protein normally found in human hair. Scientists isolate an 11 amino acid stretch from the larger natural protein, copy its exact sequence, then build it with standard amino acids in a controlled reactor. Because it is made synthetically, no animal or human tissue is needed, and the final material is highly pure and consistent from batch to batch.
The ingredient first appeared in advanced hair care research during the early 2000s when formulators searched for smaller protein pieces that could penetrate the hair shaft more easily than full-size proteins. Its success in improving softness and strength led to broader use in premium conditioners and treatments. Today it turns up in rinse-off conditioners, leave-in creams, hair masks, strengthening serums, and color-protecting sprays where it supports smoothness and resilience without weighing hair down.
Sh-Oligopeptide-90 Sp’s Cosmetic Benefits/Uses
In cosmetics Sh-Oligopeptide-90 Sp is valued for one key action.
Hair conditioning: The peptide helps fill in worn areas along the cuticle, boosting smoothness and manageability. By mimicking part of hair’s own keratin structure it can temporarily reinforce weak spots, reduce breakage from brushing, and leave strands looking shinier and healthier.
Who Can Use Sh-Oligopeptide-90 Sp
Because Sh-Oligopeptide-90 Sp is non comedogenic, fragrance free and applied to hair rather than facial skin, it is generally suitable for all scalp types including oily, dry and sensitive. People prone to eczema or psoriasis on the scalp usually tolerate the peptide well since it is highly purified and used at low concentrations.
The ingredient is produced entirely through laboratory synthesis with no animal or human by products, making it appropriate for both vegans and vegetarians.
No evidence suggests that topical use during pregnancy or while breastfeeding poses a risk, yet this is not medical advice. Anyone who is pregnant or nursing should show the full ingredient list of any hair product to a qualified healthcare provider before regular use, just to be safe.
Sh-Oligopeptide-90 Sp does not absorb UV light or alter the skin’s response to sunlight so it is not linked to photosensitivity. It also plays well with common salon chemical services such as color, perm or straightening treatments and will not strip dye molecules.
Potential Side Effects/Adverse Reactions
Reactions to topical Sh-Oligopeptide-90 Sp vary from person to person. The points below outline potential side effects, though most users will not encounter them when the ingredient is properly formulated and used as directed.
- Transient scalp itching or redness in very sensitive individuals
- Allergic contact dermatitis in those already allergic to specific peptides or preservatives present in the finished product
- Mild eye irritation if the product runs into the eyes before rinsing
- Hair stiffness or a coated feel when overused in leave in products, due to excess protein layering on the cuticle
If any adverse reaction occurs discontinue use at once and consult a healthcare professional.
Comedogenic Rating
Rating: 0/5. Sh-Oligopeptide-90 Sp is a small water-soluble peptide that contains no oils, waxes or fatty acids so it does not clog pores. It rinses off cleanly and, even when left on, sits on the hair shaft rather than the skin, keeping pore blockage highly unlikely.
This makes the ingredient suitable for people who are prone to acne or breakouts.
Most products that use the peptide are rinse-off conditioners or sprays which further minimizes any comedogenic risk by limiting skin contact.
Summary
Sh-Oligopeptide-90 Sp is a lab-crafted 11 amino acid fragment that copies part of keratin-associated protein 1-1. In hair care formulas it slips between damaged cuticle scales, lightly bonding to the surface to smooth rough spots, strengthen weak areas and add shine without heaviness.
The peptide is still found mainly in higher-end conditioners, masks and leave-ins but its steady record of improving manageability is bringing it into more mainstream lines each year.
Overall it is considered very safe with a low chance of irritation or allergy and virtually no comedogenicity. Even so, try a small patch first whenever you introduce a new product to make sure your scalp and skin agree with it.