Sodium Cyclodextrin Butylsulfonate: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 30, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Sodium Cyclodextrin Butylsulfonate?

Sodium Cyclodextrin Butylsulfonate is a modified form of beta cyclodextrin, a ring-shaped sugar molecule originally obtained from natural starch through an enzyme process. Chemists attach small sulfobutyl groups to the outside of the ring, then neutralize the mixture with sodium to create a water-friendly salt. The result is a white to off-white powder that disperses easily in both water and many water-based gels.

Cyclodextrins were first studied in the late 1800s but became interesting to the personal care industry in the 1970s when researchers learned they could trap unwanted oils and odors inside the ring. Adding the sulfobutyl group made the material even more soluble, letting formulators use lower amounts while getting better performance. Today the ingredient appears in many rinse-off and leave-on cosmetic products.

The manufacturing process starts with food-grade corn or potato starch. After enzymes cut the starch into beta cyclodextrin rings, the rings are reacted with 1,4-butane sultone. Careful control of temperature and pH links the sulfobutyl groups onto the outside of the ring. Finally, sodium hydroxide is used to neutralize the mixture and form the sodium salt, which is then purified and dried.

You will most often see Sodium Cyclodextrin Butylsulfonate in clay or sheet masks, hydrating serums, lightweight lotions, scalp tonics, deodorant sprays and anti-aging creams where it helps keep formulas fresh and comfortable on the skin.

Sodium Cyclodextrin Butylsulfonate’s Cosmetic Benefits/Uses

This ingredient serves several jobs inside a formula, each adding a different kind of value

  • Absorbent: The ring-shaped molecule can trap excess sebum, sweat and malodor molecules, helping skin feel matte and fresh
  • Preservative: By binding water and lowering the amount free for microbial growth it supports the main preservative system, helping products stay safe longer
  • Solvent: Its water-friendly outer surface improves the solubility of certain actives and fragrances, leading to clearer stable products without cloudiness
  • Cleansing: When used in cleansers and masks it lifts away dirt and oil, giving a thorough yet gentle clean that does not strip the skin

Who Can Use Sodium Cyclodextrin Butylsulfonate

Because it is light, water loving and free of heavy oils this ingredient suits most skin types, including oily, combination, normal and sensitive skin. Those with very dry skin may want to pair it with richer moisturizers since the ingredient itself does not add oil or long lasting moisture.

Sodium Cyclodextrin Butylsulfonate is made from plant starch and is processed without animal by products so it is considered suitable for both vegans and vegetarians.

Current data shows no specific risks for women who are pregnant or breastfeeding when the ingredient is used in cosmetics. Still this is not medical advice and anyone who is pregnant or nursing should ask a doctor before starting a new product just to be safe.

The molecule does not make skin more sensitive to sunlight and there are no known interactions with sunscreen filters or common actives such as retinol or vitamin C.

Potential Side Effects/Adverse Reactions

Side effects from topical Sodium Cyclodextrin Butylsulfonate can differ from person to person. The points below list potential reactions yet they are uncommon when the ingredient is used at normal cosmetic levels.

  • Mild skin dryness if used in high amounts in leave on products
  • Temporary tight feeling on very dry or compromised skin
  • Rare cases of redness or itching in individuals already prone to ingredient sensitivities
  • Eye irritation if the raw powder or a highly concentrated formula gets into the eyes

If any discomfort or irritation develops stop use right away and seek medical advice if symptoms persist.

Comedogenic Rating

Rating: 0 (non-comedogenic)

Sodium Cyclodextrin Butylsulfonate dissolves completely in water, contains no heavy oils or waxes, and rinses away easily so it cannot lodge in pores and trigger blockages. In fact its sebum-absorbing nature can leave skin feeling less oily.

Suitable for acne-prone or breakout-prone skin.

Because it often partners with other ingredients that may be richer, always consider the full product formula when assessing the chance of pore clogging.

Summary

Sodium Cyclodextrin Butylsulfonate works as an absorbent, mild preservative booster, solvent and gentle cleansing aid. Its ring structure traps excess oil and odor molecules, its sulfobutyl groups bind extra water to limit microbial growth, and the sodium salt form keeps it freely soluble so it can lift dirt without leaving residue.

While not as famous as hyaluronic acid or niacinamide, this ingredient is quietly popular in masks, serums and scalp sprays where a light clean feel is desired.

Current safety data and long global use show it is low risk for most people. Still, skin is personal so try a patch test when sampling any new product that contains it just to be safe.

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