Sodium Dihydroxypropyl Dipalmitoyl Glycerophosphate: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 30, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Sodium Dihydroxypropyl Dipalmitoyl Glycerophosphate?

Sodium Dihydroxypropyl Dipalmitoyl Glycerophosphate is a specialty ingredient created by linking naturally occurring fatty acids, glycerol and phosphate groups, then neutralizing the mixture with a touch of sodium. The result is a mild salt that combines the skin loving feel of plant derived lipids with the stability of a phosphate backbone. First explored in the early 2000s as chemists searched for gentler hair removal helpers, it soon found a niche in modern personal care labs.

To make it, manufacturers start with palmitic acid, a fatty acid most often sourced from sustainable palm or coconut oil. Through a series of controlled esterification steps the palmitic acid is joined to glycerol, then reacted with a protected phosphate. A final hydrolysis step releases the active molecule, which is converted to its sodium form for ease of use in water based formulas. The process is carefully monitored to keep by products low and purity high, giving formulators a consistent, easy to handle powder or thick liquid.

You are likely to spot Sodium Dihydroxypropyl Dipalmitoyl Glycerophosphate in products that focus on hair removal or preparing skin for it. Common examples include depilatory creams, pre shave gels, hot wax bases, soothing post wax masks and multi step at home epilation kits. Its fatty structure also lets it slip into certain body lotions and aftercare balms that promise a smoother feel after waxing or shaving.

Sodium Dihydroxypropyl Dipalmitoyl Glycerophosphate’s Cosmetic Benefits/Uses

This ingredient serves one clear purpose in beauty formulas, and it does it well.

As an epilating agent, Sodium Dihydroxypropyl Dipalmitoyl Glycerophosphate helps weaken the bond between the hair shaft and the skin surface so unwanted hair can be lifted away more easily. By softening keratin and lubricating the skin at the same time it allows depilatory creams and waxes to remove hair with less tugging, which can translate to reduced irritation, fewer ingrown hairs and a silkier after feel.

Who Can Use Sodium Dihydroxypropyl Dipalmitoyl Glycerophosphate

This epilating helper is generally well tolerated by normal, dry, oily and combination skin because its fatty structure doubles as a light emollient, cushioning the skin while hair is removed. Those with very sensitive or compromised skin should proceed with caution, as any active that loosens hair can heighten reactivity in already fragile areas.

The molecule is synthesized from plant sourced palmitic acid and contains no animal by products, making it suitable for both vegans and vegetarians. Manufacturers often highlight its palm or coconut origin for that reason.

Current safety data show no specific risks for pregnant or breastfeeding women when the ingredient is used in wash off or rinse off hair removal formats. This is not medical advice and anyone who is expecting or nursing should review new personal care choices with a qualified doctor first, just to be safe.

Sodium Dihydroxypropyl Dipalmitoyl Glycerophosphate does not absorb UV light and is not linked to photosensitivity, so it will not make skin more prone to sunburn on its own.

The ingredient is fragrance free, gluten free and non volatile, so it rarely triggers respiratory concerns during at home use.

Potential Side Effects/Adverse Reactions

Responses to topical Sodium Dihydroxypropyl Dipalmitoyl Glycerophosphate can differ from person to person. The effects listed below are possible but unlikely for most users when the ingredient is properly formulated and used as directed.

  • Transient redness or warmth in the treated area
  • Mild stinging or tingling during application
  • Temporary dry patches or flakiness after hair removal
  • Allergic contact dermatitis in individuals sensitive to fatty acid derivatives
  • Heightened sensitivity when layered with strong acids or retinoids

If you notice persistent irritation or any unusual reaction stop using the product and consult a healthcare professional.

Comedogenic Rating

Rating: 2 / 5

Sodium Dihydroxypropyl Dipalmitoyl Glycerophosphate contains palmitic acid residues, a fatty component that can sometimes contribute to clogged pores, yet the molecule is highly modified and partially water soluble thanks to its glycerophosphate and sodium groups. This keeps it from sitting on the skin like a heavy oil, so the likelihood of blocked pores is low for most users. The rating reflects a small but not zero chance of congestion, especially if the ingredient is blended with richer waxes or butters in a formula.

Acne prone individuals can usually tolerate products containing this ingredient, but they may prefer lighter rinse off formats such as depilatory creams rather than leave on balms.

Because the ingredient often appears alongside other occlusive agents in hair removal products, those with very reactive or blemish prone skin may want to check the full ingredient list to gauge overall pore friendliness.

Summary

Sodium Dihydroxypropyl Dipalmitoyl Glycerophosphate mainly serves as an epilating helper that softens keratin in the hair shaft while its fatty tail adds slip to reduce tugging during removal. This dual action lets depilatory creams and waxes lift hair more easily and leave skin feeling smoother.

Use of the ingredient is still fairly niche, showing up mostly in modern at home hair removal kits rather than mainstream skincare, yet formulators value its balance of performance and mildness.

Current data suggest it is safe for the vast majority of users in rinse off or short contact products with only rare reports of irritation. As with any new cosmetic, performing a small patch test when trying a product that contains this ingredient is a smart step to confirm personal compatibility.

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