Sodium Hyaluronate Crosspolymer-2: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 30, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Sodium Hyaluronate Crosspolymer-2?

Sodium Hyaluronate Crosspolymer-2 is a modified form of hyaluronic acid, the well known molecule naturally present in our skin that helps it hold water. In this version several hyaluronic acid chains are linked together with diglycidyl ether, creating a three-dimensional network that can trap and slowly release moisture. The raw materials usually start with fermented plant sugars that are first converted into hyaluronic acid, then crosslinked under controlled laboratory conditions to form the polymer. This ingredient began appearing in skin care about a decade ago as chemists searched for longer lasting hydration compared with standard hyaluronic acid, which tends to wash away quickly. Today it is found in lightweight serums, sheet masks, eye creams, anti-aging moisturizers and after-sun treatments where a deep, sustained dose of water is desired.

Sodium Hyaluronate Crosspolymer-2’s Cosmetic Benefits/Uses

This ingredient brings one key function to skin care formulas.

As a humectant it pulls water from the environment or underlying skin layers and locks it into the crosslinked network. The result is ongoing hydration that can help plump fine lines, improve skin elasticity and give a smoother, fresher look for longer than regular hyaluronic acid.

Who Can Use Sodium Hyaluronate Crosspolymer-2

This ingredient is generally suitable for all skin types including dry, normal, combination and oily because its lightweight water-binding nature hydrates without leaving a greasy film. Sensitive skin usually tolerates it well as it is non-irritating and fragrance free yet very reactive or compromised skin should still introduce new products gradually to watch for any personal sensitivities. It poses no special issues for acne-prone skin since it is water based and non-comedogenic.

The raw material is produced by fermenting plant sugars rather than sourcing from animal tissue so it meets vegan and vegetarian standards.

No specific warnings exist for pregnant or breastfeeding women when the ingredient is used topically at typical cosmetic levels. This is not medical advice and anyone who is expecting or nursing should discuss any skincare product with a healthcare professional to be completely safe.

Sodium Hyaluronate Crosspolymer-2 does not increase photosensitivity so daytime use is fine, though daily sunscreen is always recommended for overall skin health.

Potential Side Effects/Adverse Reactions

Reactions to topical Sodium Hyaluronate Crosspolymer-2 vary from person to person. The effects below are possible but uncommon when the ingredient is correctly formulated and applied.

  • Mild redness or flushing especially if the formula contains other active ingredients that boost circulation
  • Transient tingling in very dry or compromised skin as moisture balance shifts
  • Rare allergic response such as itching or small hives if an individual is hypersensitive to hyaluronic derivatives
  • Product pilling when layered over silicone-rich or high oil content products which may lead to surface irritation from rubbing

If any uncomfortable reaction occurs discontinue use and consult a healthcare professional if symptoms persist or worsen.

Comedogenic Rating

Rating: 0 out of 5. Sodium Hyaluronate Crosspolymer-2 is a water-soluble polymer with no oil content so it does not block pores or create the kind of film that can trap sebum and debris. Its large molecular size keeps it on the skin’s surface where it simply attracts and holds water rather than sinking into follicles. Because of this it is considered non-comedogenic and is generally suitable for people who are prone to acne or breakouts. The only time pore issues might arise is if the ingredient is blended into a formula that also contains heavy oils or waxes which could offset its non-clogging nature.

Summary

Sodium Hyaluronate Crosspolymer-2 is mainly used as a humectant that draws moisture to the skin then slowly releases it thanks to its three-dimensional crosslinked structure. This extended hydration helps keep the surface smooth, plump and comfortable for longer than standard hyaluronic acid.

Although it is not as common as traditional hyaluronic acid it is gaining popularity in serums, masks and lightweight creams because consumers appreciate longer lasting hydration without greasy residue.

The ingredient is regarded as very safe for topical use with minimal risk of irritation or pore clogging. As with any new skincare product it is wise to perform a small patch test first to confirm personal compatibility.

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