Sodium Isostearoamphoacetate: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 30, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Sodium Isostearoamphoacetate?

Sodium Isostearoamphoacetate is a mild, water-soluble ingredient made from isostearic acid, a fatty acid often sourced from vegetable oils, and a small amino acid-like molecule that is then neutralized with sodium. The result is a gentle surfactant that carries both positive and negative charges, allowing it to work well in water and oil environments. It first showed up in personal care labs in the late 1990s when formulators were looking for skin and hair cleansers that would foam well yet feel soft and low-irritating. Production involves reacting isostearic acid with an amine, adding a carboxymethyl group for extra water compatibility, then finishing with sodium to create the final salt. You will usually see it in sulfate-free shampoos, body washes, facial cleansers, bubble baths, baby washes, micellar waters, shaving creams, makeup removers, and some conditioning masks.

Sodium Isostearoamphoacetate’s Cosmetic Benefits/Uses

This multitasking ingredient supports a formula in several helpful ways

  • Cleansing: Loosens and lifts oil, dirt and leftover products so they rinse away without stripping skin or hair
  • Foaming: Builds a creamy lather that gives users a clean, fresh feel even in low-sulfate or sulfate-free formulas
  • Hair conditioning: Leaves a soft, detangled feel on hair strands which can reduce static and improve manageability
  • Foam boosting: Stabilizes bubbles created by other surfactants so the foam lasts longer and feels richer

Who Can Use Sodium Isostearoamphoacetate

This ingredient is gentle enough for most skin types including dry, oily, sensitive and combination. It cleans without pulling away too much natural oil so even reactive skin tends to tolerate it well. At the moment there are no reports suggesting it is unsuitable for any specific skin type.

Because it is typically made from plant-derived fatty acids and no animal by-products are needed during manufacturing, formulas using Sodium Isostearoamphoacetate are usually acceptable for vegans and vegetarians. Always check the full ingredient list to make sure the rest of the product lines up with your lifestyle choices.

Current safety data show no known risks for women who are pregnant or breastfeeding when the ingredient is used topically in rinse-off or leave-on products. This is not medical advice; expectant or nursing mothers should still run any skincare or haircare product past their doctor just to be safe.

Sodium Isostearoamphoacetate does not increase photosensitivity, so it will not make skin more likely to burn in the sun. It also plays well with most other common cosmetic ingredients, so special layering rules are rarely needed.

Potential Side Effects/Adverse Reactions

Reactions to topical Sodium Isostearoamphoacetate can vary from person to person. The points below outline potential side effects, though they are uncommon when the ingredient is used correctly in a well-formulated product.

  • Mild skin redness or stinging, especially on very sensitive or compromised skin
  • Temporary dryness if the formula is left on the skin for an extended period before rinsing
  • Allergic contact dermatitis in individuals already sensitized to similar surfactants
  • Eye irritation if the product accidentally gets into the eyes

If you notice any persistent irritation or discomfort while using a product that contains Sodium Isostearoamphoacetate stop use and consult a healthcare professional for guidance.

Comedogenic Rating

Rating: 0 / 5. Sodium Isostearoamphoacetate is a fully water-soluble surfactant with a relatively large molecular size and no oily or waxy residues, so it is highly unlikely to block pores or trigger comedones. In practical use it rinses cleanly and does not form films on the skin, which keeps the risk of clogging minimal.

That makes it generally suitable for people who are prone to acne or breakouts. Individual reactions can still vary, but the ingredient itself is considered non-comedogenic.

Keep in mind that a product’s total formula, not just one ingredient, decides its pore-clogging potential. Heavy oils, silicones or thick butters paired with this surfactant could raise the overall comedogenicity of the finished product.

Summary

Sodium Isostearoamphoacetate is a gentle, plant-derived surfactant that cleanses, creates stable foam, boosts lather and leaves hair feeling soft and detangled. It achieves these effects by carrying both positive and negative charges, letting it attract oil and water at the same time then wash everything away without harshness.

While not a headline ingredient, it shows up quietly in many sulfate-free shampoos, baby washes, micellar waters and sensitive-skin cleansers where mildness is a top priority. Formulators like it because it adds creaminess and slip without irritation.

Current safety assessments find it low risk for most users with only rare reports of sensitivity. As with any new skincare or haircare product it is wise to do a quick patch test first to be sure your skin agrees with the full formula.

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