Sodium O-Phenylphenate: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 30, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Sodium O-Phenylphenate?

Sodium O-Phenylphenate is the sodium salt of o-phenylphenol, a molecule made of two connected benzene rings. It is produced by reacting o-phenylphenol with sodium hydroxide, which converts the acidic hydrogen into a stable salt that dissolves well in water. The ingredient is fully synthetic, created in controlled factory settings that follow cosmetic quality standards.

Its story in personal care began in the mid-1900s when chemists noticed the parent compound’s ability to keep surfaces free of unwanted microbes. Over time formulators adopted the sodium version because it mixes more easily into water-based products while keeping the same protective qualities.

Today you will most often spot Sodium O-Phenylphenate in items that need to stay fresh during storage such as facial cleansers, body lotions, wet wipes, deodorant sprays, shampoos and some rinse-off masks. It is usually added in very small amounts alongside other ingredients that condition or perfume the skin.

Sodium O-Phenylphenate’s Cosmetic Benefits/Uses

Sodium O-Phenylphenate plays a single yet important role in cosmetics.

As an antimicrobial it helps stop the growth of bacteria and fungi within the product. This protection keeps creams and liquids safe to use for their intended shelf life so the texture, scent and effectiveness remain consistent every time you open the jar or bottle.

Who Can Use Sodium O-Phenylphenate

Sodium O-Phenylphenate is generally considered suitable for all skin types because it is used in very low amounts and is rinsed or wiped off in most formulas. Oily and combination skins appreciate its ability to keep products clean while dry or mature skins benefit from the stable shelf life it provides to richer creams. Those with very sensitive or compromised skin should still pay attention to how their skin feels, as any preservative can sometimes trigger irritation in highly reactive complexions.

The ingredient is fully synthetic with no raw materials derived from animals so it aligns with vegan and vegetarian lifestyles.

Current safety reviews show no specific concerns for women who are pregnant or breastfeeding when the ingredient is used within the tiny levels allowed by cosmetic regulations. Absorption through intact skin is minimal. This is not medical advice and anyone who is expecting or nursing should ask a healthcare professional before adding new products to the routine.

Sodium O-Phenylphenate does not increase photosensitivity and there are no reports of it making skin more prone to sunburn.

Potential Side Effects/Adverse Reactions

Reactions to topical Sodium O-Phenylphenate vary from person to person. The points below outline potential side effects to be aware of although most users will not experience them when the ingredient is used at the approved low levels.

  • Skin irritation
  • Redness or itching in individuals with preservative sensitivities
  • Contact dermatitis after repeated or prolonged exposure in rare cases
  • Eye stinging if the product accidentally enters the eyes

If discomfort or any listed reaction occurs stop use immediately and consult a healthcare professional.

Comedogenic Rating

Rating: 0 out of 5

Sodium O-Phenylphenate is water soluble and used at very low concentrations, so it does not leave an oily or occlusive film that could block pores. As a result it is considered non-comedogenic and is unlikely to trigger whiteheads or blackheads. This makes it suitable for people who are prone to acne or breakouts. No pore-clogging data or user reports contradict this assessment.

Summary

Sodium O-Phenylphenate is an antimicrobial preservative that keeps cosmetics free of bacteria and fungi by disrupting microbial cell membranes. Thanks to its water solubility it blends smoothly into cleansers, lotions, wipes, sprays and shampoos, extending their shelf life without altering texture or scent.

The ingredient is moderately common: you will mainly see it in practical everyday items rather than high-profile serums or luxury creams. Formulators value its reliability and cost effectiveness but many brands now favor newer broad-spectrum systems which can make Sodium O-Phenylphenate appear less trendy.

Current research and regulatory reviews conclude that Sodium O-Phenylphenate is safe at the small percentages allowed in cosmetics with minimal risk of irritation for most users. Even so skin can be unpredictable so it is wise to patch test any new product that contains this or any other preservative.

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