Sodium Piperazinoethyl Linoleate Ethylsulfonate: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 30, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Sodium Piperazinoethyl Linoleate Ethylsulfonate?

Sodium Piperazinoethyl Linoleate Ethylsulfonate is a lab made ingredient created by linking linoleic acid, a fatty acid that occurs naturally in plant oils, with a small piperazine based molecule and finishing the structure with a sulfonate salt. The result is a water soluble form of linoleic acid that blends smoothly into modern skin care formulas. Chemists began experimenting with this type of molecule in the early 2000s while looking for gentle ways to reinforce the skin barrier without using heavy oils. Production starts with vegetable sourced linoleic acid that is reacted with piperazine, followed by an ethylsulfonation step and neutralization with sodium to make a stable powder that dissolves in water. You will most often see it in lightweight moisturizers, soothing serums, calming face masks and after sun lotions where there is a need for barrier support without greasy feel.

Sodium Piperazinoethyl Linoleate Ethylsulfonate’s Cosmetic Benefits/Uses

The main role of this ingredient is skin protecting. By pairing linoleic acid with a water friendly backbone it forms a thin breathable layer that helps limit moisture loss and shields skin from everyday irritants. This can make a formula feel more comforting, reduce tightness after cleansing and support a healthier looking complexion over time.

Who Can Use Sodium Piperazinoethyl Linoleate Ethylsulfonate

This ingredient is gentle enough for nearly all skin types. Dry and sensitive complexions often appreciate the lightweight barrier support while combination and oily skin benefit from the non greasy feel. Extremely reactive or allergy-prone skin should still proceed carefully if they have known sensitivities to fatty acids or sulfonates, though such reactions are uncommon.

Because the raw materials come from plant oils and no animal derived agents are used in the synthesis, Sodium Piperazinoethyl Linoleate Ethylsulfonate is considered suitable for vegans and vegetarians.

Current research offers no evidence that the ingredient poses a risk to women who are pregnant or breastfeeding when used topically at the low levels found in cosmetics. This is not medical advice and anyone who is expecting or nursing should review their routine with a healthcare professional before starting new products just to be safe.

The molecule is not known to increase photosensitivity and can be worn both day and night without raising sun-related concerns. It also plays nicely with common actives such as niacinamide, ceramides and most gentle exfoliating acids.

Potential Side Effects/Adverse Reactions

Side effects from topical use of Sodium Piperazinoethyl Linoleate Ethylsulfonate differ from person to person. The points below describe potential reactions, yet they are unlikely to occur for the average user when the ingredient is formulated and used correctly.

  • Mild redness or warmth shortly after application
  • Transient stinging on compromised or freshly exfoliated skin
  • Itching in individuals with a rare sensitivity to linoleic acid derivatives
  • Contact dermatitis marked by swelling or persistent rash in those with sulfonate allergies
  • Eye irritation if the product accidentally migrates too close to the lash line

If any of these issues occur discontinue use immediately and seek professional medical advice if symptoms do not subside.

Comedogenic Rating

Rating: 1 / 5

The parent fatty acid, linoleic acid, is naturally light and tends to help loosen clogged sebum rather than thicken it. Turning it into a highly water soluble salt further lowers the chance of it lingering in pores or building up on skin. For that reason formulators consider Sodium Piperazinoethyl Linoleate Ethylsulfonate to be very low on the pore-clogging scale.

People who break out easily can usually use products with this ingredient without extra concern.

Keep in mind that the finished product formula matters too. Heavy occlusives or waxes paired with this molecule could still feel greasy or trap debris even if the ingredient itself is non-comedogenic.

Summary

Sodium Piperazinoethyl Linoleate Ethylsulfonate is a water compatible spin on linoleic acid that cushions the skin surface, limits moisture loss and helps ward off everyday irritants. By grafting the fatty acid onto a piperazine backbone and adding a sulfonate salt chemists created a lightweight barrier helper that feels almost weightless in serums, gels and lotions.

It is not a household name yet but it is quietly gaining ground in modern calming and after-sun formulas where brands want the benefits of an essential fatty acid without an oily finish.

Current evidence shows it is safe at the low levels used in cosmetics, with only rare cases of irritation or allergy. As with any new skincare ingredient it is smart to perform a small patch test before full-face use, especially if your skin is sensitive or reactive.

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