Sodium Scymnol Sulfate: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 30, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Sodium Scymnol Sulfate?

Sodium Scymnol Sulfate is a salt form of scymnol, a molecule that belongs to the sterol family. It is derived from cholestane, a structure related to cholesterol, and is combined with a sulfate group to improve its water solubility. First isolated from shark tissue in the 1980s, scymnol drew attention because of its soothing effect on skin. Cosmetic chemists later converted it into the sodium salt to make it easier to blend into water-based formulas.

Commercial production starts with plant-sourced sterols that are modified in a series of gentle steps to mirror the natural scymnol structure. The final material is purified then neutralized with sodium to form the stable powder used in skincare labs.

You will most often find Sodium Scymnol Sulfate in lightweight moisturizers, calming serums, masks and leave-on spot treatments aimed at reducing the look of redness or irritation. Because it is water soluble it fits well into gels, lotions and other oil-free products.

Sodium Scymnol Sulfate’s Cosmetic Benefits/Uses

This ingredient plays one main role in personal care formulas.

As a skin conditioning agent, Sodium Scymnol Sulfate helps keep the surface of the skin soft smooth and comfortable. It supports the skin’s natural moisture balance and can reduce the feeling of tightness that sometimes follows cleansing. Formulators often include it in products designed for sensitive or blemish-prone skin because its gentle nature pairs well with actives that might otherwise cause dryness.

Who Can Use Sodium Scymnol Sulfate

Sodium Scymnol Sulfate is gentle enough for most skin types including dry, oily, combination, sensitive and mature skin. Its water loving structure means it does not clog pores so even those prone to breakouts can normally use it without worry. There are no groups for whom the ingredient is considered outright unsuitable however anyone with a known allergy to sterol based compounds should proceed with caution.

Modern suppliers make Sodium Scymnol Sulfate from plant derived sterols rather than shark tissue so the finished material is suitable for vegans and vegetarians. If this point is important to you check that the brand specifies a plant origin on its ingredient sourcing statement.

No research has shown a risk to women who are pregnant or breastfeeding when the ingredient is used on intact skin. Absorption is minimal and the molecule is not known to interfere with hormones. That said this is not medical advice and anyone who is pregnant or nursing should have a quick chat with a healthcare provider before adding a new skincare product, just to be on the safe side.

Sodium Scymnol Sulfate does not cause photosensitivity and can be used in both morning and evening routines. It also plays nicely with common actives like niacinamide retinol and salicylic acid.

Potential Side Effects/Adverse Reactions

Side effects and reactions to topical Sodium Scymnol Sulfate can vary from person to person. The following points outline potential issues though most users will not run into any of them when the ingredient is formulated and used as intended.

  • Mild redness or warmth shortly after application
  • Temporary stinging on broken or freshly exfoliated skin
  • Itching or small bumps in those with a sulfate sensitivity
  • Allergic contact dermatitis in rare cases

If you notice any of the above while using a product that contains Sodium Scymnol Sulfate stop using the product and consult a medical professional.

Comedogenic Rating

Rating: 0 (non-comedogenic)

Sodium Scymnol Sulfate is fully water soluble and does not leave an oily film on the skin so it has no tendency to block pores. It is used at low levels and rinses cleanly from the skin’s surface which further reduces any risk of buildup.

Because of this it is generally considered safe for people who are prone to acne or frequent breakouts.

One extra point worth noting is that finished formulas can still clog pores if they contain heavy oils or waxes. Check the full ingredient list rather than judging a product on this single component.

Summary

Sodium Scymnol Sulfate is mainly a skin conditioning agent that helps keep skin soft comfortable and balanced. Its water friendly structure lets it attract and hold moisture lightly soothing the surface without feeling greasy. Thanks to its gentle profile it often finds a home in products aimed at sensitive or blemish prone skin.

The ingredient is something of a quiet achiever. It is not as famous as big name hydrators like hyaluronic acid yet formulators value it for its calm steady performance especially in oil free or gel textures.

Current safety data shows it to be low risk for most users with little chance of irritation or pore blockage. Still everyone’s skin is different so it is smart to do a small patch test when you try a new product that features Sodium Scymnol Sulfate.

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