What Is Sr-Cat Polypeptide-2?
Sr-Cat Polypeptide-2 is a lab made version of a naturally occurring protein called vascular endothelial growth factor that is found in cats. Scientists recreate the cat gene then insert it into a harmless strain of E. coli. As the bacteria grow they produce the single chain protein, which is later purified, filtered and made safe for skin and hair products. Chemically it is a chain of up to 189 amino acids that can form small disulfide bridges and may carry simple sugar groups, giving it stability and activity.
The move from medical research to beauty shelves began when studies on growth factors showed they could soothe irritation and support the skin’s own repair signals. Formulators soon explored gentler, cosmetic grade versions that would not require prescriptions. Because bacteria based fermentation is cost friendly and avoids animal extraction, Sr-Cat Polypeptide-2 became a practical choice for brands aiming to add high tech peptides to their lines.
Today you will most often spot this ingredient in lightweight anti aging serums, restorative face masks, leave-on conditioners, scalp tonics, nourishing shampoos and daily moisturizers that target dryness or environmental stress.
Sr-Cat Polypeptide-2’s Cosmetic Benefits/Uses
In formulas Sr-Cat Polypeptide-2 works in a few key ways that can improve both skin and hair care products.
- Antioxidant: Helps neutralize free radicals created by UV light and pollution which can lead to dull tone or early fine lines. By reducing this stress it supports a fresher, healthier looking complexion.
- Hair Conditioning: Coats strands with a light protein layer that adds softness and smoothness, making hair easier to detangle and less prone to breakage.
- Skin Protecting: Forms a breathable film that locks in moisture and shields the surface from harsh weather or styling heat, supporting the skin barrier and calming visible irritation.
Who Can Use Sr-Cat Polypeptide-2
Sr-Cat Polypeptide-2 is considered gentle enough for most skin types including oily, dry or combination skin because it is non-comedogenic and light in texture. Sensitive skin generally tolerates it well thanks to its soothing film-forming action, though anyone with a known protein allergy should proceed cautiously.
The ingredient is produced through bacterial fermentation so no animal tissues are used at any step. That makes it suitable for both vegans and vegetarians.
Current data shows no specific risks for pregnant or breastfeeding women when the peptide is applied topically in cosmetic concentrations. Still this is not medical advice and anyone who is expecting or nursing should review any new product with a qualified healthcare provider.
Sr-Cat Polypeptide-2 does not increase photosensitivity so there is no extra need for sun avoidance beyond normal daily SPF habits. It is water soluble and rinses away easily which means it will not build up or interfere with most other skincare steps.
Potential Side Effects/Adverse Reactions
Responses to topical Sr-Cat Polypeptide-2 can differ from person to person. The effects listed below are uncommon and most users will not notice any of them when the ingredient is formulated correctly.
- Irritation or redness: A temporary warm feeling or slight flushing may occur on very reactive skin
- Allergic contact dermatitis: Rare but possible in individuals sensitive to recombinant proteins or preservative systems used alongside the peptide
- Mild stinging around the eyes: Can happen if the product migrates into the eye area before it has dried
- Product buildup on hair shafts: Overuse in leave-in conditioners might leave fine hair feeling weighed down
- Interaction with high strength acids: Very low pH products can destabilize the peptide making it less effective or causing formula separation
If any uncomfortable reaction develops stop using the product and seek advice from a healthcare professional.
Comedogenic Rating
Rating: 0/5
Sr-Cat Polypeptide-2 is a large water-soluble protein that lacks oily carriers, waxes or fatty acids which are the main culprits behind clogged pores. Because it sits on the surface as a light breathable film then rinses away with water it does not block follicles or encourage blackheads. For these reasons it earns a solid zero on the comedogenic scale.
That means the ingredient is generally suitable for people prone to acne or frequent breakouts.
Only in very heavy leave-on formulas packed with other occlusive agents could buildup become a concern, but in standard skincare concentrations the peptide itself contributes no pore-clogging risk.
Summary
Sr-Cat Polypeptide-2 is a lab cultured version of a cat-derived growth factor that acts as an antioxidant, a protective film former and a light protein conditioner. It mops up free radicals to keep skin tone bright, lays down a micro-thin shield that boosts barrier strength and coats hair fibers for smoother feel and less breakage.
You will mainly find it in niche anti aging serums, restorative masks and premium scalp tonics rather than mass market lines, yet its presence is growing as brands look for biotech peptides that are vegan friendly and cost effective.
Current research points to a very low irritation profile and no comedogenicity, making it safe for most users including sensitive skin and acne prone types. Still every formula is different so it is smart to patch test a new product to rule out personal sensitivities.