Stearamidopropyl Trimonium Methosulfate: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 30, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Stearamidopropyl Trimonium Methosulfate?

Stearamidopropyl Trimonium Methosulfate is a quaternary ammonium salt made from stearic acid, a fatty acid most often taken from vegetable oils such as coconut or sustainable palm. Chemists first began using this ingredient in hair care in the late 1980s when they were searching for a gentler, more easily biodegradable alternative to older conditioning agents. To create it, stearic acid is reacted with a small nitrogen-containing molecule to form stearamidopropyl amine, which is then quaternised by methyl sulfate. The end result is a positively charged ingredient that is water dispersible, making it ideal for rinse-off and leave-on products.

You will most often see Stearamidopropyl Trimonium Methosulfate in hair conditioners, deep-treatment masks, leave-in creams, curl-defining lotions, anti-frizz serums and some gentle cleansing conditioners. Because it is lighter than many traditional quats it is also used in lightweight skin moisturisers where a silky after-feel is desired.

Stearamidopropyl Trimonium Methosulfate’s Cosmetic Benefits/Uses

This ingredient carries a positive charge that lets it cling to negatively charged hair and skin surfaces, delivering targeted benefits even after rinsing.

  • Antistatic – neutralises static electricity on hair strands so they lie smoothly rather than flying away, which helps reduce frizz and makes styling easier
  • Hair conditioning – forms a thin, velvety film that smooths the cuticle, boosts softness, improves detangling and adds a light, non-greasy slip without weighing hair down

Who Can Use Stearamidopropyl Trimonium Methosulfate

This ingredient is considered gentle enough for all skin and hair types including dry, normal and oily. Its lightweight film rarely clogs pores so it is usually fine for combination and acne prone skin too. People with a known sensitivity to quaternary ammonium compounds should avoid it as they may be more prone to irritation.

Stearamidopropyl Trimonium Methosulfate is often sourced from coconut or sustainable palm oil which makes it suitable for vegans and vegetarians when clearly listed as plant derived. If animal derived stearic acid is used the product would not meet vegan standards so check the label or brand statement if this is a concern.

No data suggest any specific risk for women who are pregnant or breastfeeding when the ingredient is used in rinse off or leave on cosmetics at typical concentrations. This is not medical advice and anyone who is pregnant or nursing should show their doctor any personal care products they plan to use just to be on the safe side.

The molecule does not increase photosensitivity, so wearing it during the day does not require extra sun precautions beyond normal good practice.

Potential Side Effects/Adverse Reactions

Side effects and reactions to the topical application of Stearamidopropyl Trimonium Methosulfate can vary from person to person. The issues listed below are only potential effects and most users will not experience them when the ingredient is used correctly in a well formulated product.

  • Mild skin irritation in individuals who have very sensitive skin or a pre existing allergy to quaternary ammonium compounds
  • Eye stinging if the product accidentally gets into the eyes before rinsing
  • Scalp build up in rare cases if very heavy leave in products are layered frequently without proper cleansing
  • Contact dermatitis in the unlikely event of an allergic response marked by redness, itching or small bumps

If any uncomfortable reaction occurs stop using the product and seek advice from a healthcare professional.

Comedogenic Rating

Rating: 1 / 5

Stearamidopropyl Trimonium Methosulfate is water dispersible and forms a very light film that rinses away easily. It does not behave like heavier oils or waxes that can block pores so the likelihood of it triggering comedones is low. The small amount that may remain on skin is typically insufficient to trap dead cells or sebum.

Suitable for acne-prone or breakout-prone skin in most cases.

Because the molecule is cationic it tends to bind to hair and rinse off skin rather than sinking deep into follicles, further reducing clogging risk.

Summary

Stearamidopropyl Trimonium Methosulfate is mainly valued for its antistatic and hair-conditioning abilities. Its positive charge helps it cling to hair and skin, smoothing cuticles, softening strands and reducing flyaways while leaving a non-greasy feel.

The ingredient is moderately popular in modern conditioners, leave-ins and some lightweight lotions, especially in products marketed as gentle or clean because it is considered more biodegradable than older quats.

Current research and decades of use show it is generally safe, with low irritation and very low comedogenic potential when used at typical cosmetic levels. As with any new personal care product it is smart to perform a patch test first and discontinue use if irritation occurs.

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