T-Butylphenyl Glyceryl Ether: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 30, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is T-Butylphenyl Glyceryl Ether?

T-Butylphenyl glyceryl ether is a synthetic ingredient created by bonding a glycerin-like backbone to a tert-butyl phenyl group. This clever pairing gives the molecule properties of both glycerin, well known for attracting moisture, and a phenolic ring that can help neutralize free radicals. The compound does not come from plants or animals but is produced in a lab through a controlled reaction between propanediol and a tert-butyl substituted phenol, followed by purification to remove any residual reactants.

Interest in the ingredient grew in the early 2000s when formulators looked for multitasking molecules that could simplify product labels. Its dual action as a water binder and free radical scavenger quickly made it a favorite for brands aiming to cut down on the number of separate additives in a formula.

T-Butylphenyl glyceryl ether typically appears in lightweight moisturizers, anti-aging serums, sheet masks, eye creams, and after-sun treatments. Because it is compatible with a wide pH range and both water and oil phases, it fits easily into gels, emulsions, and even some anhydrous balms.

T-Butylphenyl Glyceryl Ether’s Cosmetic Benefits/Uses

This ingredient is valued for two main actions in skincare formulations

  • Antioxidant – The phenolic portion of the molecule helps mop up free radicals generated by UV light and pollution. By limiting oxidative stress, it supports the skin’s own defenses and can help slow the look of premature aging such as fine lines or dullness
  • Humectant – The glycerin-like end attracts and holds water at the skin surface. This boosts immediate hydration, leaves skin feeling plumper, and improves the spreadability of creams and serums

Who Can Use T-Butylphenyl Glyceryl Ether

This multitasking molecule is considered gentle and is generally well tolerated by all major skin types, including oily, dry, combination and sensitive skin. Its water-binding action can give dry skin a moisture boost while the light, non-greasy feel will not weigh down oily complexions. There are no known reasons it would be unsuitable for darker or lighter skin tones.

The ingredient is made entirely in a lab and contains no animal-derived matter, so it is suitable for both vegans and vegetarians. Most brands also list it as cruelty-free, though checking the full product for certification labels is always a good idea.

No specific warnings have been issued for pregnant or breastfeeding women. The molecule stays on the surface of the skin and is not expected to enter the bloodstream in meaningful amounts. Still, this is not medical advice. Anyone who is pregnant or nursing should show the full product ingredient list to a qualified healthcare provider before use.

T-Butylphenyl glyceryl ether does not make skin more sensitive to sunlight and can be used morning or night without raising the risk of sunburn. Of course, daily sunscreen is still important for overall skin health.

Potential Side Effects/Adverse Reactions

Responses to any topical ingredient can differ from person to person. The points below outline potential side effects linked to T-Butylphenyl glyceryl ether, but most users experience none of these issues when the ingredient is used at the low levels typically found in finished products.

  • Temporary redness or warmth in very reactive skin
  • Mild stinging if applied to broken or freshly exfoliated skin
  • Contact dermatitis in individuals allergic to phenolic compounds, although this is rare
  • Eye irritation if the product accidentally gets into the eyes
  • Potential interaction with strong acids or retinoids that are layered directly on top, which could increase overall irritation

If any of these reactions occur stop using the product immediately and seek advice from a medical professional if symptoms persist or worsen

Comedogenic Rating

Rating: 1 / 5

T-Butylphenyl glyceryl ether is largely water compatible and behaves more like glycerin than an oil so it does not readily clog pores. The small phenyl ring could in theory add a trace of occlusivity which is why it is not rated a perfect zero, yet tests and user feedback show very little tendency to create blackheads or whiteheads.

Suitable for acne-prone or breakout-prone skin in most cases.

Formulators usually include this ingredient at low percentages alongside lightweight emulsifiers so the finished product texture stays fluid and non-greasy which further reduces any pore-blocking risk.

Summary

T-Butylphenyl glyceryl ether serves two key roles: it pulls moisture into the upper layers of skin thanks to its glycerin-like backbone and it helps neutralize skin-aging free radicals through its phenolic ring. This one-two punch lets brands replace separate humectants and antioxidants with a single multitasker.

While not as mainstream as classic glycerin or vitamin E it is quietly gaining traction in modern serums masks and light creams because it fits into both water and oil phases and plays well with a wide pH range.

Safety data show the molecule is non-sensitizing for most users and it remains on the skin surface rather than absorbing systemically. Still it is wise to patch test any new product to rule out personal sensitivities before full-face application.

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