Thiourea: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 30, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Thiourea?

Thiourea is a small sulfur-containing compound that looks much like a grainy white powder. It is closely related to urea, the natural moisturizing factor found in our skin, but with sulfur atoms replacing some of the oxygen atoms. Early versions were first prepared in the 19th century while chemists explored new ways to use coal tar derivatives. Today thiourea is usually made in a controlled lab process where hydrogen cyanide reacts with hydrogen sulfide, then is neutralized to form the finished ingredient. Its reliable quality and purity make it suitable for modern cosmetic formulas.

Because of its special properties, thiourea shows up in products that need both water-binding and protection from microbial growth. You may find it in sheet masks, lightweight gel moisturizers, soothing after-sun lotions, men’s grooming creams and specialty treatments that aim to keep formulas fresh without heavy preservatives.

Thiourea’s Cosmetic Benefits/Uses

In skincare and haircare formulas thiourea serves two key roles that help keep products effective and pleasant to use:

  • Antimicrobial: Thiourea can slow the growth of certain bacteria and fungi, supporting overall product preservation. This helps extend shelf life and lowers the risk of spoilage so the product stays safe on your bathroom shelf.
  • Humectant: As a humectant thiourea attracts water and holds it close to the skin surface. This boost in moisture can leave skin feeling softer plumper and more comfortable especially in lightweight or oil-free products.

Who Can Use Thiourea

Thiourea is generally well tolerated by most skin types including dry oily and combination because it adds light hydration without heavy oils. Very sensitive skin or anyone with a known sulfur allergy should proceed with caution since the sulfur in thiourea could trigger irritation.

The ingredient is produced synthetically using minerals and gas feedstocks so it contains no animal by products. This makes it suitable for vegans and vegetarians.

Current safety data do not flag thiourea as a special concern for women who are pregnant or breastfeeding. Even so this is not medical advice and anyone who is expecting or nursing should show the full product list to their doctor before use just to be safe.

Thiourea is not known to increase photosensitivity and will not make skin more prone to sunburn. It can be used morning or night alongside sunscreen and other daily care products.

Potential Side Effects/Adverse Reactions

Responses to topical thiourea vary from person to person. The effects below are possible yet uncommon when the ingredient is used correctly in a finished cosmetic:

  • Skin irritation mild stinging or redness can occur particularly on already inflamed or compromised skin
  • Allergic contact dermatitis rare but possible in people sensitive to sulfur containing compounds leading to itching rash or swelling
  • Eye irritation watery or burning eyes may happen if the product accidentally gets into the eye area
  • Unpleasant odor shift in very high concentrations thiourea’s sulfur content can give products a slight sulfuric smell which some users might find off putting

If any discomfort rash or other reaction appears stop using the product and seek advice from a medical professional.

Comedogenic Rating

Rating: 0 / 5 Thiourea is fully water soluble and contains no oils or waxes that could clog pores. It sits lightly on the skin then rinses away without leaving a film that traps sebum or debris, so it earns the lowest possible score. For this reason it is considered suitable for people who are prone to acne or frequent breakouts. Because it also has mild antimicrobial action, it is unlikely to worsen blemish-causing bacteria.

Summary

Thiourea serves two main jobs in cosmetics: it pulls in moisture as a humectant and it helps curb unwanted microbes that could spoil a formula. Its small size and sulfur content let it form temporary hydrogen bonds with water keeping skin feeling hydrated, while its slight antimicrobial nature supports the product’s preservative system.

Despite these helpful traits thiourea is not a superstar ingredient you will see on every shelf. It appears mostly in niche or professional formulations where a light feel and extra preservation boost are desired.

Current data show thiourea is generally safe for topical use with only rare reports of irritation or allergy. As with any new skincare ingredient it is wise to perform a simple patch test before full use to make sure your skin agrees with it.

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