What Is Tranexamoyl Dipeptide-23?
Tranexamoyl Dipeptide-23 is a lab made ingredient created by joining tranexamic acid, a synthetic amino acid derivative, with Dipeptide-23, a tiny chain of two amino acids. The reaction links the two parts into a single molecule that can target uneven skin tone while being gentle on skin.
The story of this ingredient begins with the popularity of tranexamic acid in brightening skincare and the growing use of short peptides in anti-aging formulas. Chemists looked for a way to combine the stain-fighting power of tranexamic acid with the skin friendly qualities of a peptide. The result was Tranexamoyl Dipeptide-23, first introduced in specialized brightening serums and quickly adopted by cosmetic labs worldwide.
Production is fully synthetic and takes place in controlled facilities. Manufacturers activate tranexamic acid, couple it to the dipeptide through standard peptide chemistry, then purify the finished material and dry it into a fine powder. This controlled process keeps the ingredient free from animal products or common allergens.
You will most often find Tranexamoyl Dipeptide-23 in spot correctors, daily brightening serums, lightweight creams, sheet masks and leave-on essences aimed at fading dark spots and evening the complexion.
Tranexamoyl Dipeptide-23’s Cosmetic Benefits/Uses
Its main cosmetic role is bleaching, which in skincare terms means helping to lighten areas of excess pigment and promote a more uniform skin tone. By combining the melanin-blocking action of tranexamic acid with the skin comforting nature of a peptide, Tranexamoyl Dipeptide-23 supports formulas that target dark spots while remaining suitable for daily use.
Who Can Use Tranexamoyl Dipeptide-23
Tranexamoyl Dipeptide-23 is generally considered suitable for all skin types including normal, dry, oily, combination and sensitive because it is non abrasive and formulated to be gentle. Those with a severely compromised skin barrier or chronic inflammatory conditions should introduce it slowly as even mild brightening agents can occasionally provoke discomfort.
The ingredient is fully synthetic and produced without animal derivatives so it meets vegan and vegetarian standards.
No specific warnings exist for topical use during pregnancy or while breastfeeding. The molecule is large enough to stay in the upper layers of skin and systemic absorption is expected to be minimal. That said, research during pregnancy is limited. This is not medical advice and anyone who is pregnant or nursing should speak with a healthcare professional before adding new products to their routine to be safe.
Tranexamoyl Dipeptide-23 does not increase photosensitivity. Standard daytime sun protection is still advised because UV exposure is a major cause of the dark spots the ingredient aims to fade.
It layers well with most common actives such as niacinamide and vitamin C but pairing it with strong acids or retinoids on the same night could amplify dryness in sensitive users.
Potential Side Effects/Adverse Reactions
Reactions to topical Tranexamoyl Dipeptide-23 vary from person to person. The following list covers potential side effects yet most users experience none of these as long as the product is well formulated and used as directed.
- Mild redness or irritation in sensitive skin
- Temporary stinging or burning on application, usually subsides within minutes
- Dryness or light flaking when combined with other strong actives
- Rare allergic contact dermatitis presenting as itching or rash
If any of these reactions occur stop use immediately and consult a medical professional for advice.
Comedogenic Rating
Rating: 0/5. Tranexamoyl Dipeptide-23 is water soluble, lightweight and free of pore clogging oils or waxes, so it does not obstruct follicles or encourage buildup that can lead to comedones. Its peptide-based structure and small usage levels in formulas keep the risk of breakouts extremely low. Because of this profile it is generally suitable for acne prone or easily congested skin. Nothing in its chemistry suggests an increased likelihood of blackheads or whiteheads.
Summary
Tranexamoyl Dipeptide-23 is a brightening active that combines tranexamic acid’s melanin inhibiting power with a gentle dipeptide to fade dark spots and promote an even tone while staying kind to skin. It works by slowing excess pigment production at the source and supporting skin comfort, which lets users apply it daily without harsh effects.
The ingredient is gaining traction in targeted serums and masks but is still less common than household names like vitamin C or niacinamide. Early adopters appreciate its balance of efficacy and gentleness, so its presence is slowly expanding in new launches.
Safety data and user experience show a low risk of irritation or pore clogging, making it appropriate for most skin types including sensitive or acne prone. Still, everyone’s skin is unique. Perform a patch test when trying a new product that contains Tranexamoyl Dipeptide-23 to confirm compatibility and enjoy its brightening benefits with confidence.