Tributyl Citrate: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 30, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Tributyl Citrate?

Tributyl citrate is an ester formed when citric acid reacts with butanol, giving a clear, oily liquid with a mild odor. The citric acid usually comes from the fermentation of corn or sugar beets while the butanol is typically sourced from plant-derived sugars, so the ingredient can be classed as plant based. First introduced in the 1970s as a safe plasticiser for food wrap, it soon caught the attention of cosmetic chemists looking for a gentle alternative to phthalates. Production involves heating citric acid with an excess of butanol in the presence of an acid catalyst, then purifying the resulting liquid to cosmetic grade. Its ability to keep polymers flexible and form smooth films means you will often see it in nail polish, mascara, liquid eyeliner, peel-off masks, long-wear lip color, hairspray and certain sunscreens.

Tributyl Citrate’s Cosmetic Benefits/Uses

In beauty formulas tributyl citrate delivers several practical perks that boost performance and user experience.

  • Film forming – Creates a thin, even layer on skin, hair or nails that locks in color, improves water resistance and extends wear time so makeup and sun care stay put longer
  • Plasticiser – Softens and flexibilises resins or polymers to stop cracking and flaking which leads to smoother nail enamel, clump-free mascara and more comfortable long-wear lipstick
  • Solvent – Efficiently dissolves pigments, UV filters and fragrances helping them blend evenly and remain stable throughout a product’s shelf life

Who Can Use Tributyl Citrate

Because it is a lightweight oil that does not clog pores, tributyl citrate is generally suitable for dry, normal, combination and oily skin. Most sensitive skin also tolerates it, though people with a history of fragrance or solvent allergies should check the full ingredient list of the finished product to be sure no other trigger is present.

The citric acid base is obtained from fermented plant sugars and the butanol is likewise plant sourced, so no animal material is involved. That makes tributyl citrate acceptable for vegans and vegetarians, provided the brand follows cruelty free manufacturing practices.

Current safety reviews classify the ingredient as low risk for topical use, including in leave-on products. Pregnant or breastfeeding women can usually use cosmetics that contain it, but this is not medical advice and anyone expecting or nursing should run new products past a doctor to be safe.

Tributyl citrate does not increase photosensitivity, so normal daylight exposure is fine. It is also readily biodegradable which has made it a preferred choice in “clean” formulations.

Potential Side Effects/Adverse Reactions

Responses to any cosmetic ingredient can vary from person to person. The points below outline potential side effects of tributyl citrate in topical products, but most users will not experience them when the formula is made and used correctly.

  • Mild skin irritation such as temporary redness or stinging on very sensitive skin
  • Contact dermatitis in individuals allergic to citrates or certain solvents
  • Eye irritation if the liquid gets into the eyes while applying mascara or eyeliner
  • Nail plate dryness when used in high concentrations in nail polish remover-type products

If any of these effects occur stop using the product and consult a healthcare professional or dermatologist.

Comedogenic Rating

Rating: 0 / 5 (non-comedogenic)

Tributyl citrate is a low-viscosity ester that sits on the surface of skin then evaporates or washes away without leaving a waxy residue, so it does not obstruct pores. It also lacks long-chain fatty acids that typically feed acne bacteria, which keeps its clogging potential virtually nil.

Because of this, the ingredient is generally safe for people who are prone to acne or breakouts.

No studies report it aggravating fungal acne either, making it a flexible option in both water- and oil-based formulas.

Summary

Tributyl citrate acts as a film forming agent, plasticiser and solvent. It softens polymer chains so they spread evenly, builds a thin flexible film that boosts wear time and water resistance, and dissolves pigments or UV filters for smooth, stable blends.

While not a headline ingredient, it quietly powers a wide range of nail lacquers, mascaras, lip colours, sprays and “clean” sunscreens, valued for being plant based and biodegradable.

Current safety reviews show a very low risk profile when used at typical cosmetic levels, yet as with any new product it is smart to patch test to rule out personal sensitivities.

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