Vitis Vinifera Leaf Extract: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 30, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Vitis Vinifera Leaf Extract?

Vitis Vinifera Leaf Extract is a plant-based ingredient obtained from the leaves of the common grapevine, Vitis Vinifera L. These leaves are naturally rich in protective compounds like flavonoids, phenolic acids and small amounts of resveratrol, all of which give the plant its well-known antioxidant reputation. Historical records show that grape leaves were used in traditional skin poultices throughout the Mediterranean, and modern formulators have built on that heritage by isolating the leaf’s beneficial molecules for use in cosmetics.

The extract is typically produced by harvesting fresh or gently dried grape leaves, then macerating them in a water- or glycerin-based solvent. The mixture is filtered and concentrated to obtain a stable liquid or powder that can be easily blended into skincare products. Because grapevines are cultivated worldwide, the raw material is readily available, making the extract a sustainable option for formulators.

You will most often find Vitis Vinifera Leaf Extract in moisturizers, anti-aging serums, sheet masks, soothing gels and after-sun products where its calming and conditioning qualities can shine.

Vitis Vinifera Leaf Extract’s Cosmetic Benefits/Uses

This ingredient is prized for the way it improves how skin looks and feels.

  • Skin conditioning: The polyphenols in grape leaves help soften the skin surface, support moisture retention and leave a smooth, supple finish. By reinforcing the skin’s natural barrier, the extract can also reduce the appearance of dryness or rough patches, giving formulas a comforting, pampering touch.

Who Can Use Vitis Vinifera Leaf Extract

Grape leaf extract is considered gentle enough for most skin types including dry, normal, combination, oily and even sensitive complexions thanks to its calming polyphenols. Those with a known allergy to grapes or wine should proceed with caution as cross-reactivity can occur and may trigger irritation.

The ingredient is entirely plant derived with no animal by-products, making it suitable for vegans and vegetarians. When shopping, check the full ingredient list to be sure the overall formula stays free from animal sources.

No data suggest that topical Vitis Vinifera Leaf Extract poses a risk to pregnant or breastfeeding women, but this is not medical advice and anyone who is expecting or nursing should show their doctor any skincare product they plan to use just to be safe.

The extract is not known to increase sun sensitivity so it can be worn day or night without added photoprotective concerns, though daily sunscreen is always recommended for overall skin health.

Potential Side Effects/Adverse Reactions

Responses to Vitis Vinifera Leaf Extract vary from person to person. The points below outline potential, though uncommon, side effects when the ingredient is applied topically. When used in a well-formulated product most people will not experience these issues.

  • Allergic contact dermatitis – people with a grape allergy may notice redness, rash or swelling
  • Mild stinging or burning – usually short lived and more likely if skin is already compromised
  • Itching or dryness – rare and often linked to other actives in the same formula rather than the extract itself
  • Photosensitive rash – extremely rare but possible if combined with other sun-sensitizing ingredients

If you develop any uncomfortable reaction stop using the product and seek advice from a healthcare professional or dermatologist.

Comedogenic Rating

Rating: 0–1

Vitis Vinifera Leaf Extract is primarily made up of water-soluble polyphenols rather than heavy oils or waxes, so it does not tend to clog pores. Most finished formulas include it at low concentrations where it acts as a light, skin-conditioning antioxidant rather than an occlusive film former. For these reasons it earns a 0–1 on the comedogenic scale.

Because of this very low rating, the extract is generally considered appropriate for people who are prone to acne or breakouts.

If the extract appears in an oil-rich cream or balm the overall product may still feel heavy, but that is due to the base oils not the grape leaf extract itself.

Summary

Vitis Vinifera Leaf Extract conditions skin, adds a mild antioxidant boost and helps support a smoother surface finish by delivering polyphenols that reinforce the natural moisture barrier. Thanks to its gentle nature and plant origin it is showing up in more moisturizers, serums and soothing treatments even though it is still less famous than grape seed oil or resveratrol.

The ingredient is widely viewed as safe for topical use with a very low risk of irritation outside of true grape allergies. As with any new skincare product it is smart to perform a small patch test first to make sure your skin agrees with the full formula.

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