Acetanisole Cryst. – The Complete Guide To This Aroma Chemical

Curious about this ingredient? In this article we're explaining everything you need to know.
Updated on: July 30, 2025
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We verify all information on this page using publicly available standards from The International Fragrance Association (IFRA) and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Acetanisole Cryst?

Acetanisole Cryst. is the trade name Symrise gives to a highly purified form of 4-methoxyacetophenone, a small aromatic molecule that belongs to the ketone family. While Symrise offers this branded grade, other aroma chemical suppliers may sell comparable generic versions under similar names.

The material is produced through an acetylation step that joins an anisole ring with an acetic fragment. In practical terms manufacturers start with anisole then run it through a Friedel–Crafts style reaction, refine the result by distillation and finally allow it to solidify into crystals. The finished product reaches a gas-chromatography purity of at least 99 percent, which is why the letters “Cryst.” highlight its crystalline state.

At room temperature the ingredient forms small, pale white shards that look a little like coarse sea salt. When gently warmed those crystals melt into a clear liquid, making it easy to dose in the production lab.

Acetanisole appears in a surprising range of scented goods. Perfumers reach for it in fine fragrance formulas while home and personal care chemists rely on it for shampoos, soaps, detergents and even candle blends. Because it is stable in both water-based and oil-based systems its popularity has remained steady for decades.

Shelf life is generous: when kept in a sealed container away from light and heat the crystals typically stay within specification for around three to four years before any noticeable decline occurs. As for cost, it sits in the lower-to-mid price bracket so it does not usually strain a project budget.

Acetanisole Cryst’s Scent Description

This material is generally classified within the floral family.

On a paper blotter the opening impression is soft and powdery, evoking freshly picked lilac petals dusted with icing sugar. Within a minute or two a creamy mimosa note comes forward, laced with the faint almond-like sweetness you find in tonka beans. As the scent settles a subtle touch of heliotrope appears, giving a whisper of vanilla frosting that keeps things cozy rather than gourmand.

Perfume notes are often grouped into top, middle and base phases. Top notes flash off in the first fifteen minutes, middle notes form the heart that lasts a few hours and base notes linger the longest. Acetanisole Cryst. sits firmly in the middle note slot. It arrives after the bright top accord has faded and supports the heart of the composition for two to four hours before gradually tapering into the drydown.

Projection is moderate. On skin or fabric it creates an aura noticeable at conversational distance without filling a room. Longevity is solid for a middle note, usually persisting six to eight hours in a well-built perfume and considerably longer in less volatile formats like soaps and candles.

How & Where To Use Acetanisole Cryst.

Perfumers reach for Acetanisole Cryst. when they want a smooth floral heart that links bright top notes to warmer bases. It slips neatly into lilac or mimosa accords, fills out heliotrope themes and adds an almond-like sweetness to tonka or vanilla blends. Because the material is quiet but persistent it is often chosen to soften sharp jasmine or neroli facets without changing the character of the overall bouquet.

The ingredient excels in feminine florals, spring bouquets and powdery orientals yet it is also helpful in masculine fougères where a touch of floral roundness is needed under citrus and lavender. Its moderate projection lets it support the centre of the perfume without stealing focus, which is why many perfumers use it instead of louder options such as heliotropin or benzyl salicylate when subtlety matters.

Symrise recommends using up to 2 percent of the total concentrate. In practice many formulas sit between 0.1 – 1.0 percent. At trace levels it brings a creamy undertone that few people can pick out on its own. Around 0.5 percent the lilac and mimosa facets become obvious. Push it past 1.5 percent and the note can feel cool and metallic, which may clash with delicate fruits or airy musks. Overdosing can also flatten the top accord, making the perfume smell heavy from the start.

Outside fine fragrance the material finds a home in soaps, shampoos, candles and fabric care because it holds up well in alkaline and high-heat processes. In candles it melts easily into wax and throws a soft floral scent when burning. It performs less well in fresh citrus splash colognes where its powdery character can feel out of place.

Preparation is simple. Warm the bottle in a water bath at about 40 °C if the crystals have clumped, then weigh the melted liquid straight into your diluent. It dissolves quickly in ethanol and most perfume oils. Always make a 10 percent solution for weighing accuracy and faster blending. Keep the stock solution capped tightly to prevent oxidation.

Safety Information

Always dilute Acetanisole Cryst. before smelling it. Avoid direct sniffing from the bottle and work in a well-ventilated space so vapors do not build up. Wear disposable gloves and protective glasses to keep the material off your skin and out of your eyes.

Like many aroma chemicals this ketone can cause skin irritation or sensitisation in some people. Brief exposure to low concentrations is generally considered safe yet prolonged or high-level exposure may lead to headaches, nausea or dermatitis. If you are pregnant or breastfeeding consult a healthcare professional before handling any fragrance raw materials.

Wash hands after use and keep containers closed when not in use. In case of accidental contact rinse the affected area with plenty of water and seek medical advice if redness or discomfort persists. Spills can be absorbed with paper towels or inert material then disposed of according to local regulations.

For the most accurate and current guidance always read the Safety Data Sheet supplied with your batch and check back for updates. Follow IFRA guidelines on maximum usage levels for each product category to ensure your creation is both enjoyable and safe.

How To Store & Dispose of Acetanisole Cryst.

Store Acetanisole Cryst. in a cool dark cupboard or cabinet away from direct sunlight and heat sources. A steady room temperature works well but a fridge can add extra months of freshness if you have the space. Make sure the bottle returns to room temperature before you open it to avoid moisture getting inside.

Use screw caps with polycone liners for every stock solution. They form a tight seal that keeps out air and stops leaks. Avoid glass dropper tops because they let in oxygen and can drip down the threads. Fill bottles as close to the top as practical so less air sits above the liquid. Less air means less oxidation and a longer usable life.

Label each container clearly. Include the name Acetanisole Cryst. the date you opened it and any hazard phrases shown on the Safety Data Sheet. Good labels prevent mix ups and help anyone else in the lab handle the material correctly.

Small spills can be wiped up with paper towels then placed in general waste if local rules allow. For larger amounts soak them up with sand or kitty litter and bag the material before disposal. Acetanisole Cryst. is readily biodegradable so it breaks down in normal waste treatment systems yet you should never pour it down the drain unless your local authority confirms it is safe to do so.

Empty bottles should be triple rinsed with ethanol before recycling or discarding. Rinse liquid can go into your next cleaning alcohol batch so nothing is wasted. Keep all disposal records on file to show that you follow local environmental laws.

Summary

Acetanisole Cryst. is a high purity floral ketone sold by Symrise. It smells like a gentle mix of lilac mimosa heliotrope and a hint of sweet tonka. In perfume work it acts as a quiet middle note that links bright tops to warmer bases while adding creamy depth.

The ingredient stays stable in most finished goods from fine fragrance to soap and candles. It costs less than many specialty florals which helps keep formulas on budget. Use levels rarely exceed 1 percent and you can push to 2 percent if you need more lift but watch for a cool metallic edge at high doses.

Longevity is good and the material handles heat and alkaline wash bases without breaking down. Keep it cool sealed and out of light to stretch shelf life and remember that it is readily biodegradable which makes end of life handling simpler.

You can buy Acetanisole Cryst. in bulk direct from Symrise. Smaller hobby sizes appear at fragrance supply houses and from generic makers who sell under similar names. Whether you are trialing a new spring floral or rounding out a powdery fougère this versatile crystal has earned its spot on the perfumer bench.

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