Acetyl Mannosylerythritol Lipid: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 23, 2025
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All information on this page is verified using The Personal Care Products Council's (PCPC) INCI database. Our ingredient analyses are based exclusively on PCPC's technical data to ensure accuracy and reliability.

What Is Acetyl Mannosylerythritol Lipid?

Acetyl Mannosylerythritol Lipid is a plant derived surfactant classified as a glycolipid. Chemically it is an acetylated form of mannosylerythritol lipid, which is a sugar linked to fatty acid chains. These lipids are naturally produced by certain yeast species that live on leaves and in soil. Japanese researchers first isolated them in the late 1980s while looking for mild surfactants that showed skin friendly properties. Over time formulators noticed that adding an extra acetyl group made the molecule even more stable and easier to blend into creams and shampoos, which opened the door for cosmetic use.

The modern production process starts with fermenting non GMO plant sugars such as glucose or glycerin with a specific yeast strain. After the yeast makes the raw glycolipid, it is purified, then reacted with acetic acid to attach the acetyl group. The final ingredient is a pale yellow waxy solid that melts easily into water in oil or oil in water systems.

Thanks to its gentle cleansing action and skin friendly profile you will find Acetyl Mannosylerythritol Lipid in facial cleansers, micellar waters, sulfate free shampoos, sheet masks, moisturizing lotions, anti aging emulsions, leave in hair treatments and even makeup removers. It helps these products stay stable, feel silky and rinse off without leaving a film.

Acetyl Mannosylerythritol Lipid’s Cosmetic Benefits/Uses

Formulators value this multitasking glycolipid for several reasons:

  • Emulsion stabilising: It strengthens the bond between water and oil phases so creams stay smooth and do not split while sitting on the shelf or in your bathroom
  • Hair conditioning: The lipid portion coats strands lightly improving slip and reducing frizz without weighing hair down making it useful in conditioners and styling products
  • Skin conditioning: Its sugar backbone attracts water helping skin hold onto moisture so formulas feel hydrating and leave a soft finish
  • Cleansing: As a mild surfactant it lifts away dirt and excess oil while staying gentle so skin and scalp feel clean yet comfortable

Who Can Use Acetyl Mannosylerythritol Lipid

This glycolipid is considered gentle enough for every skin type including dry, oily, combination and sensitive skin. Because it provides light hydration without leaving a greasy residue it works well for dehydrated yet acne-prone complexions too. No specific skin type is thought to be incompatible with it

The ingredient is produced by fermenting plant sugars with yeast, then acetylating the resulting lipid. No animal-derived matter is involved at any stage so products using it can be labeled suitable for vegans and vegetarians

Current safety data shows no issues for women who are pregnant or breastfeeding when the ingredient is used as directed in rinse-off or leave-on products. This is not medical advice and anyone who is pregnant or nursing should run their skincare routine past a doctor to be on the safe side

Acetyl Mannosylerythritol Lipid is non-photosensitising so it does not make skin more sensitive to the sun. It also plays nicely with common actives like niacinamide, vitamin C and retinoids, making it easy to slot into most routines

Potential Side Effects/Adverse Reactions

Side effects and reactions to the topical application of Acetyl Mannosylerythritol Lipid can vary from person to person. The points below list potential issues only; when the ingredient is formulated correctly most users will not experience any negative effects

  • Mild skin irritation such as redness or itching in very sensitive individuals
  • Allergic contact dermatitis for those with a rare sensitivity to yeast-derived ingredients
  • Transient eye stinging if the product accidentally gets into the eyes before rinsing
  • Scalp buildup or flat hair feel when overused in leave-in products on very fine hair

If you experience any discomfort or adverse reaction stop using the product and consult a healthcare professional

Comedogenic Rating

Rating: 1/5

Acetyl Mannosylerythritol Lipid is a lightweight glycolipid that blends well into both water and oil phases and rinses clean without leaving an occlusive film. Its molecular structure is too bulky to lodge easily inside pores and it has a naturally high HLB balance that keeps it from building up on skin. These traits translate to a very low chance of clogging pores, so most acne-prone users can use it without worry. People extremely sensitive to any lipids may still prefer to monitor their skin, but for the majority it is considered breakout-friendly.

Because it also acts as a mild surfactant it can actually help lift away excess sebum in cleansers, further reducing congestion risk.

Summary

Acetyl Mannosylerythritol Lipid is a multitasker that stabilises emulsions so lotions stay smooth, conditions skin and hair by adding light moisture, and cleanses gently thanks to its sugar-lipid structure. Its ability to do all this while remaining mild has earned it a place in sulfate-free shampoos, micellar waters, and modern moisturisers, though it is still something of a niche ingredient compared with long-time staples like glycerin or coco-glucoside.

Current research and in-market use show it to be safe for all skin types, including sensitive, with a very low comedogenic rating and no known photo-reactivity. As with any new skincare component it is wise to patch test a fresh product to make sure your individual skin tolerates it well.

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