Acetylated Lanolin: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 23, 2025
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All information on this page is verified using The Personal Care Products Council's (PCPC) INCI database. Our ingredient analyses are based exclusively on PCPC's technical data to ensure accuracy and reliability.

What Is Acetylated Lanolin?

Acetylated Lanolin is a soft wax made by reacting natural lanolin with acetic acid. Lanolin itself is the protective oil secreted by sheep to keep their wool water resistant. Chemists began refining lanolin in the early 1900s, but it was in the mid-century that they discovered acetylation makes the oil lighter, less sticky and easier to blend into creams and lotions. To create Acetylated Lanolin, purified lanolin is combined with acetic anhydride under controlled heat, which swaps some of the oil’s fatty acids for acetate groups. The result is an ingredient that melts near skin temperature and spreads smoothly.

You will find Acetylated Lanolin in rich face and body moisturizers, lip balms, hand creams, conditioning hair masks, leave-in treatments, styling pomades and some makeup products like cream blush or foundation sticks where a soft glide is needed.

Acetylated Lanolin’s Cosmetic Benefits/Uses

This ingredient pulls its weight in a formula thanks to the following functions

  • Hair conditioning – coats strands to add slip, tame frizz and boost softness so hair feels smoother and looks shinier
  • Emollient – fills tiny gaps between skin cells which makes skin feel silky, flexible and hydrated
  • Occlusive – forms a breathable film on skin that slows water loss helping lock in moisture for longer comfort

Who Can Use Acetylated Lanolin

Acetylated Lanolin suits normal, dry and mature skin thanks to its strong moisture sealing ability. Combination skin can benefit when it is applied only to drier zones. Very oily or acne prone skin may find it too rich because its waxy texture can trap sebum inside pores and trigger breakouts.

Because it is derived from sheep wool grease, Acetylated Lanolin is not considered vegan or vegetarian friendly. Anyone following a plant based lifestyle may prefer a synthetic or plant sourced alternative with similar emollient properties.

The ingredient is generally viewed as safe for pregnant or breastfeeding women when used topically in cosmetics, although research on this specific derivative is limited. This information is not medical advice, so expectant or nursing mothers should show any product containing Acetylated Lanolin to their healthcare provider before use.

Acetylated Lanolin does not make skin more sensitive to sunlight and it has no known interactions with UV filters, so it will not increase the risk of sunburn. It is also odorless once blended into a formula, making it suitable for those sensitive to fragrance ingredients.

Potential Side Effects/Adverse Reactions

Reactions to topical Acetylated Lanolin vary from person to person. The effects listed below are only potential issues and most people will not experience them when the ingredient is used at standard cosmetic levels.

  • Pore blockage leading to blackheads or pimples in acne prone skin
  • Allergic contact dermatitis in individuals sensitive to wool alcohols
  • General skin irritation such as redness itching or burning
  • Folliculitis, an inflammation of hair follicles particularly on the body
  • Eye stinging or watering if the product accidentally enters the eyes

If any of these effects occur stop using the product and seek advice from a healthcare professional.

Comedogenic Rating

Rating: 4 / 5

Acetylated Lanolin sits on the upper end of the comedogenic scale because its waxy semi-solid texture can mix with sebum and cling to the lining of pores. Although the acetylation step makes it lighter than raw lanolin, the molecule is still large and sticky enough to trap oil and dead skin cells which encourages blockages. For this reason people who routinely deal with whiteheads blackheads or cystic breakouts will likely find it unsuitable. Skin that is dry or mature and not prone to congestion usually tolerates it well.

Extra note: formula type matters. In a rinse-off shampoo or conditioner Acetylated Lanolin is less likely to cause issues than in a rich leave-on balm applied to the T-zone.

Summary

Acetylated Lanolin conditions hair softens skin and forms a moisture-locking shield. It achieves this because its fatty acid structure glides easily over cuticles and skin cells then settles into tiny gaps to smooth roughness while its waxy film slows down water loss.

The ingredient enjoys steady use in lip products heavy creams and hairstyling formulas, though its animal origin and breakout potential keep it from becoming a mainstream superstar.

When sourced and purified correctly it is considered safe for topical use with irritation or allergy being uncommon. As with any new cosmetic it is wise to patch test first especially if your skin is sensitive or acne prone.

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