Acrylamidomethyl Cellulose Acetate Butyrate: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 23, 2025
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All information on this page is verified using publicly available nomenclature standards and reference materials from The Personal Care Products Council (PCPC) and the European Commission's CosIng database. Our analyses are based on technical data from these sources to ensure accuracy and reliability.

What Is Acrylamidomethyl Cellulose Acetate Butyrate?

Acrylamidomethyl Cellulose Acetate Butyrate is a specialty derivative of cellulose, the natural fiber found in wood pulp and cotton. Chemists first turned cellulose into cellulose acetate butyrate for use in paints and protective coatings because it created clear flexible films. By attaching small acrylamidomethyl groups to that backbone, the material gained even better adhesion and water resistance, making it attractive for personal care labs in the late 1990s.

The manufacturing process starts with purified cellulose that is reacted with acetic and butyric anhydrides to introduce acetate and butyrate groups. A controlled grafting step then links acrylamidomethyl units to some of the remaining hydroxyl sites. The result is a white free-flowing powder that disperses easily in common cosmetic solvents.

Because of its film-forming strength this ingredient shows up in long-wear makeup such as foundations, eyeliners, mascaras and liquid lipsticks. It also appears in nail lacquers, hair styling sprays, transfer-resistant sunscreens, peel-off face masks and certain anti-aging serums where a light invisible layer can smooth skin and lock in actives.

Acrylamidomethyl Cellulose Acetate Butyrate’s Cosmetic Benefits/Uses

In cosmetic formulas Acrylamidomethyl Cellulose Acetate Butyrate offers one key performance benefit. As a film former it creates a thin flexible shield on the surface of skin hair or nails. This layer holds pigments in place for longer wear, adds gloss, reduces smudging, limits moisture loss and boosts water resistance so products stay put through sweat or humidity.

Who Can Use Acrylamidomethyl Cellulose Acetate Butyrate

This film former is considered gentle enough for most skin types including oily dry combination and normal. Because it sits on top of the skin rather than soaking in, it rarely upsets sensitive or redness-prone complexions, though anyone with a known allergy to cellulose derivatives should steer clear. The ingredient is plant-derived so it is suitable for vegans and vegetarians, and no animal testing is required for its manufacture under current regulations.

Pregnant or breastfeeding individuals can generally use products containing Acrylamidomethyl Cellulose Acetate Butyrate since it is not absorbed in meaningful amounts. That said this is not medical advice and those expecting or nursing should confirm any skincare choice with their physician to be safe.

The material does not make skin more prone to sunburn and it can even boost the water resistance of sunscreens. It has no known interactions with common actives like retinol or vitamin C, and it is odorless so it will not clash with fragrance-free routines.

Potential Side Effects/Adverse Reactions

Responses to topical Acrylamidomethyl Cellulose Acetate Butyrate vary from person to person. The points below outline potential side effects that could occur, though they are uncommon when the ingredient is used correctly and at approved levels.

  • Mild skin itching or redness in individuals allergic to cellulose esters
  • Stinging if applied to broken or freshly exfoliated skin
  • Temporary eye watering if the dry powder is inhaled during DIY handling
  • Product buildup on hair or lashes leading to a stiff feel when overapplied

If any irritation or discomfort appears stop using the product and seek medical guidance if symptoms persist.

Comedogenic Rating

Rating: 1 out of 5. Acrylamidomethyl Cellulose Acetate Butyrate is a large film-forming polymer that stays on the surface of skin rather than seeping into pores, so it is very unlikely to clog them. A rating of 1 reflects this low risk while acknowledging that heavy layers of any film former can trap oil or debris if the rest of the formula is overly greasy.

Because of its low rating this ingredient is generally fine for people who are prone to acne or breakouts.

Keep in mind the final product matters: if the polymer is blended with rich oils or waxes the overall formula could still feel heavy on acne-prone skin even though the polymer itself is not a pore blocker.

Summary

Acrylamidomethyl Cellulose Acetate Butyrate is used in beauty products as a strong yet flexible film former that locks pigments in place, boosts water resistance and helps active ingredients stay on the surface where they can work longer. It does this by forming an invisible lattice over skin hair or nails that is clear, breathable and resistant to sweat or rubbing.

The polymer is popular in long-wear makeup like liquid lipstick, eyeliner, mascara and transfer-proof foundation though you will see it less often in everyday lotions or cleansers. Its niche use means it is well known to formulators of color cosmetics but most shoppers have never heard of it.

Safety studies and in-market history show it is low in irritation and non-sensitising for the vast majority of users. Still, everyone’s skin is unique so it is smart to patch test any new product containing this ingredient before applying it to the whole face.

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