Adamantanyl Hydroxylterephthalamide: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 23, 2025
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All information on this page is verified using The Personal Care Products Council's (PCPC) INCI database. Our ingredient analyses are based exclusively on PCPC's technical data to ensure accuracy and reliability.

What Is Adamantanyl Hydroxylterephthalamide?

Adamantanyl Hydroxylterephthalamide is a lab-made organic compound created by joining an adamantane ring, known for its rigid diamond-like shape, with a hydroxylterephthalamide group that carries antioxidant traits. Chemists first explored it in the early 2000s while looking for stable molecules that could soak up excess oil and block free radicals. Its performance in test creams quickly drew attention, leading to wider cosmetic use over the past decade.

The ingredient is produced through a multi-step synthesis. Starting with petroleum-derived adamantane, manufacturers add functional groups through controlled reactions, then bind the modified ring to terephthalic acid and amide units. The final material is purified, milled into a fine powder and checked for purity before going into finished formulas.

You are most likely to spot Adamantanyl Hydroxylterephthalamide in clay or sheet masks aimed at oily skin, lightweight daily moisturizers, anti-aging serums and protective day creams. It also appears in targeted treatments meant to calm pollution stress on the face and in primer lotions that promise a smooth matte finish.

Adamantanyl Hydroxylterephthalamide’s Cosmetic Benefits/Uses

This multitasker brings several perks to skin care formulas:

  • Anti-Sebum: The molecule’s porous adamantane core can bind excess surface oil helping to keep shine down and reduce the greasy feel of products. This makes it useful in mattifying lotions and primers for people who struggle with midday slickness.
  • Antioxidant: By neutralizing free radicals from sunlight and pollution it helps slow the look of early aging signs such as fine lines and dullness. The added antioxidant support pairs well with vitamin C or E in brightening or firming serums.
  • Skin Protecting: It forms a light invisible film that shields skin from particulate matter in the air and helps lock in moisture. This boost in barrier support can leave the face feeling softer and more resilient over time.

Who Can Use Adamantanyl Hydroxylterephthalamide

Thanks to its oil-absorbing yet lightweight nature, Adamantanyl Hydroxylterephthalamide suits oily, combination and normal skin best. Dry or easily irritated skin can still benefit from its antioxidant shield, but pair it with richer moisturizers to avoid a tight feel. The ingredient is non animal-derived and produced entirely through synthetic chemistry, so both vegans and vegetarians can use products containing it with confidence.

No data currently link topical Adamantanyl Hydroxylterephthalamide to hormonal disruption, so it is generally considered acceptable for pregnant or breastfeeding women. This is not medical advice; anyone who is expecting or nursing should confirm suitability with a healthcare professional before adding new skincare to their routine.

The molecule does not increase skin’s sensitivity to sunlight, so it is not classified as photosensitizing. Standard daytime sun protection is still recommended to guard against UV damage. The ingredient also plays well with common actives like niacinamide, vitamin C and retinoids, giving formulators flexibility when building multi-benefit products.

Potential Side Effects/Adverse Reactions

Individual responses to topical Adamantanyl Hydroxylterephthalamide can vary. The points below outline potential side effects, but most users will not encounter these issues when the ingredient is properly formulated and used as directed.

  • Mild transient dryness if used in high concentrations on already dehydrated skin
  • Temporary tight or matte sensation that some users may perceive as discomfort
  • Rare cases of redness or flushing in highly sensitive skin types
  • Uncommon stinging when applied to broken or compromised skin barriers

If any irritation or unexpected reaction occurs discontinue use and consult a medical professional for guidance.

Comedogenic Rating

Rating: 1/5. Adamantanyl Hydroxylterephthalamide has a rigid, non-oily structure that does not clog pores and it is typically used at low concentrations. Its matte film sits on the surface without mixing with sebum, so it is unlikely to trap dead cells or bacteria inside follicles.

Because of this low rating the ingredient is generally considered suitable for people who are prone to acne or breakouts.

Formulas that blend it with heavy butters or waxes may raise the overall comedogenic risk, so check the full ingredient list when evaluating a product.

Summary

Adamantanyl Hydroxylterephthalamide tackles excess oil, neutralizes free radicals and creates a light protective barrier. The adamantane core soaks up surface sebum, the hydroxylterephthalamide group scavenges damaging molecules from UV and pollution and the resulting film helps shield skin from dirt while locking in moisture.

Though still a niche addition compared with headline actives like niacinamide it is showing up more often in mattifying moisturizers, anti-pollution serums and city-proof day creams as brands look for multi-functional ingredients.

Current research and in-market use point to a strong safety profile with only rare minor reactions. As with any new product it is wise to patch test first to be on the safe side and to spot any personal sensitivities early.

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