Adipic Acid/Isophthalic Acid/Neopentyl Glycol/Trimethylolpropane Copolymer: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 23, 2025
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All information on this page is verified using The Personal Care Products Council's (PCPC) INCI database. Our ingredient analyses are based exclusively on PCPC's technical data to ensure accuracy and reliability.

What Is Adipic Acid/Isophthalic Acid/Neopentyl Glycol/Trimethylolpropane Copolymer?

Adipic Acid/Isophthalic Acid/Neopentyl Glycol/Trimethylolpropane Copolymer is a mouthful of a name for a synthetic resin created by linking together four building blocks: adipic acid, isophthalic acid, neopentyl glycol and trimethylolpropane. Through a controlled heating process called esterification, these small molecules join to form a long chain, or copolymer, that behaves like a flexible film when it dries on skin or hair. All starting materials are petrochemical in origin, though the final product is a solid resin or a dispersion that mixes smoothly into water based or alcohol based formulas.

Polymers like this one have been used since the late 1960s in paints and varnishes. Their ability to form clear, durable films quickly caught the attention of cosmetic chemists looking for ways to hold hairstyles in place without flaking or to add a protective coating to skin care products. Over the years manufacturers fine tuned the polymer’s ratio of acids and glycols, giving the beauty industry a version that is easier to solubilize, has low odor and leaves a pleasant, lightweight feel.

Today you will most often spot this ingredient in hair sprays, styling gels, mousses and setting lotions, where it acts as the backbone of the hold. It also appears in some long-wear makeup, liquid eyeliners, peel-off face masks and transfer-resistant sunscreens whenever a flexible yet sturdy film is needed.

Adipic Acid/Isophthalic Acid/Neopentyl Glycol/Trimethylolpropane Copolymer’s Cosmetic Benefits/Uses

This copolymer supports product performance in a couple of key ways

  • Film forming: Once the formula dries this polymer creates an invisible layer that resists water, sweat and rubbing. The film helps makeup stay put, keeps sunscreen from washing off too soon and lets peel-off masks lift away in one piece
  • Hair fixing: In styling products the polymer binds individual strands together, delivering hold and shape memory. It helps tame frizz, maintain curls or spikes and provides touchable control without a stiff helmet feel

Who Can Use Adipic Acid/Isophthalic Acid/Neopentyl Glycol/Trimethylolpropane Copolymer

This polymer is considered suitable for most skin types including dry, oily and combination because it sits on the surface without sinking deep into pores or altering skin’s natural balance. Sensitive or highly reactive skin can usually tolerate it as well since the molecule is too large to penetrate yet it is smart to keep the rest of the formula in mind because added fragrance or alcohol, not the polymer itself, is often what causes stinging.

The ingredient is fully synthetic and contains no animal derived raw materials so it is generally acceptable for vegans and vegetarians. Manufacturing suppliers do not report the use of animal testing for this specific polymer though finished product policies will vary by brand.

Current safety data show no link between topical use of the polymer and problems during pregnancy or breastfeeding. Still this is not medical advice and anyone who is pregnant or nursing should discuss new products with a healthcare professional before adding them to a routine.

The polymer does not increase skin’s sensitivity to sunlight and can even help water resistant sunscreens stay on longer. It is odorless, colorless and free of common allergens such as nuts, gluten or soy.

Potential Side Effects/Adverse Reactions

Side effects and reactions to topical Adipic Acid/Isophthalic Acid/Neopentyl Glycol/Trimethylolpropane Copolymer vary from person to person. The points below list potential issues only and most users will not notice any of them when the ingredient is used correctly in a well formulated product.

  • Mild scalp or skin dryness
  • Temporary flaking or white residue if over applied in hair sprays
  • Build up on hair shafts that may require a clarifying shampoo
  • Rare contact irritation such as redness or itching
  • Eye discomfort if aerosol mist accidentally reaches the eyes

If any of these effects occur stop using the product and seek guidance from a healthcare professional if symptoms persist or worsen

Comedogenic Rating

Rating: 1 out of 5. The molecule is a large, water-dispersible film former that stays on the surface instead of seeping into follicles where blackheads start. It contains no heavy oils or waxes so the likelihood of clogging pores is very low, yet a thin occlusive layer can trap existing sebum for some users which is why it is not rated a perfect zero.

Suitable for acne-prone skin in most cases.

The ingredient is usually blended at low levels alongside volatile solvents that evaporate quickly, further reducing any pore-blocking potential.

Summary

Adipic Acid/Isophthalic Acid/Neopentyl Glycol/Trimethylolpropane Copolymer works mainly as a film former and hair fixative. Once the carrier liquid flashes off the polymer links together to create a flexible shield that anchors makeup, boosts water resistance in sunscreen and locks hairstyles in place without stiffness.

It is moderately popular in styling sprays, gels and certain long-wear makeup but you will not see it in every product on the shelf because brands often rotate through several similar polymers to reach different texture goals.

Current research and decades of cosmetic use show it to be safe for topical application on healthy skin and hair with minimal risk of irritation or pore clogging. As with any new cosmetic it is smart to patch test first to ensure personal compatibility.

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