Agaricus Blazei/Ganoderma Lucidum/Multipileum Ferment Extract: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 23, 2025
Share:
Inside this article:

All information on this page is verified using The Personal Care Products Council's (PCPC) INCI database. Our ingredient analyses are based exclusively on PCPC's technical data to ensure accuracy and reliability.

What Is Agaricus Blazei/Ganoderma Lucidum/Multipileum Ferment Extract?

Agaricus Blazei/Ganoderma Lucidum/Multipileum Ferment Extract is a fermented blend made from three well known mushrooms: Agaricus blazei, Ganoderma lucidum (often called reishi) and Ganoderma multipileum. During fermentation friendly microorganisms break down the mushroom material and release skin friendly compounds such as polysaccharides, amino acids, vitamins and natural enzymes. This process creates a liquid extract that is easier for the skin to accept than raw mushroom powders.

Mushrooms have been prized in many cultures for centuries, mainly for wellness drinks and tonics. Cosmetic chemists noticed their calming and conditioning traits in the 1990s and began testing fermented versions for skincare. Fermentation not only lowers the extract’s odor and color but also boosts its stability, which is why the ingredient gained a spot in modern formulas.

To produce the extract, the three mushrooms are cleaned, finely milled and mixed with water and a starter culture. After a controlled warm-tank fermentation that can last several days, the broth is filtered to remove solids, then concentrated and either spray-dried into a powder or kept as a liquid.

You are most likely to see Agaricus Blazei/Ganoderma Lucidum/Multipileum Ferment Extract on the ingredient list of gentle facial cleansers, micellar waters, foaming face washes, sheet masks, hydrating lotions, lightweight serums and multipurpose creams that aim to purify while leaving the skin soft.

Agaricus Blazei/Ganoderma Lucidum/Multipileum Ferment Extract’s Cosmetic Benefits/Uses

This fermented mushroom blend supports formulas in two main ways:

  • Cleansing: The natural sugars and amino acids produced during fermentation help loosen surface dirt and excess oil, allowing cleansers to rinse away grime without stripping moisture. This makes the ingredient suitable for daily face washes meant for normal to sensitive skin.
  • Emulsifying: The extract can stabilize oil and water mixtures, helping creams and lotions stay smooth and uniform. By holding the emulsion together it improves texture, spreads evenly on the skin and extends shelf life without relying on heavy synthetic emulsifiers.

Who Can Use Agaricus Blazei/Ganoderma Lucidum/Multipileum Ferment Extract

This gentle ferment suits most skin types. Its mild cleansing action works well for oily, combination and normal skin, while the low irritation profile makes it friendly toward sensitive skin too. Very dry skin can also use it, but will likely need richer moisturizers alongside because the extract itself is not deeply occlusive. Those prone to stubborn fungal acne may want to watch for flare-ups since the ingredient is derived from fungi, though the risk is low because the extract contains no live spores.

The ingredient is completely plant based. It comes from mushrooms and the standard fermentation medium is made from water and plant sugars, so it is considered suitable for vegans and vegetarians.

Current data shows no specific concerns for women who are pregnant or breastfeeding when this ingredient is applied topically. Nonetheless this is not medical advice and expectant or nursing mothers should have any skincare product reviewed by their doctor to be extra safe.

Agaricus Blazei/Ganoderma Lucidum/Multipileum Ferment Extract does not increase sensitivity to sunlight, so it will not make the skin more prone to sunburn. Standard daytime sunscreen habits are still recommended for overall skin health.

Potential Side Effects/Adverse Reactions

Responses to topical Agaricus Blazei/Ganoderma Lucidum/Multipileum Ferment Extract vary from person to person. The points below outline potential side effects, but most users will not experience them when the ingredient is properly formulated and used as intended.

  • Redness or mild irritation in very sensitive skin
  • Itching or tingling linked to an allergy to mushrooms or fermented ingredients
  • Rare swelling or hives in individuals with a known mushroom sensitivity
  • Possible clogging of pores in users extremely prone to fungal acne

If any of these reactions occur the product should be rinsed off, use should be stopped and a healthcare professional consulted if symptoms persist or worsen.

Comedogenic Rating

Rating: 1 / 5

Agaricus Blazei/Ganoderma Lucidum/Multipileum Ferment Extract is chiefly water based and contains mostly lightweight polysaccharides, amino acids and enzymes rather than heavy oils or waxes. These molecules rinse cleanly and are unlikely to block pores, giving the ingredient a low comedogenic score of 1. The only caveat is that the natural sugars may, in rare cases, encourage the yeast that drives fungal acne, though this is far from common.

Overall this extract is generally suitable for skin that is prone to regular acne or breakouts.

No additional data suggests it interacts with common acne treatments or sunscreen actives, so it can be layered with typical regimens without issue.

Summary

Agaricus Blazei/Ganoderma Lucidum/Multipileum Ferment Extract works mainly as a gentle cleanser and a plant derived emulsifier. The fermentation process unlocks small, bio-available sugars and amino acids that help lift surface grime while the natural gum-like compounds steady oil-water mixtures so creams stay smooth.

Although mushroom ferments are gaining attention, this particular triple-mushroom blend is still a niche pick found more in K-beauty and indie formulas than in mainstream drugstore lines.

Current research and user reports show it to be low risk with very few irritation or clogging issues. As with any new skincare ingredient it is wise to patch test first to make sure your skin agrees with it.

Was this article helpful?
More from Glooshi:
ADVERTISEMENT
Get all our top headlines in beauty.
Delivered right to your inbox each week. Zero spam, all goodness, opt-out at anytime.
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Get the latest beauty news, top product recommendations & brand-exclusive discount codes direct to your inbox.
Send good feedback:

All feedback is greatly appreciated, anonymous, and will be used to improve the quality of our articles.

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Send bad feedback:

All feedback is greatly appreciated, anonymous, and will be used to improve the quality of our articles.

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Search