Aluminum Zirconium Tetrachlorohydrex Gly: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 23, 2025
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All information on this page is verified using The Personal Care Products Council's (PCPC) INCI database. Our ingredient analyses are based exclusively on PCPC's technical data to ensure accuracy and reliability.

What Is Aluminum Zirconium Tetrachlorohydrex Gly?

Aluminum Zirconium Tetrachlorohydrex Gly is a salt that forms when aluminum zirconium tetrachlorohydrate reacts with the amino acid glycine. The result is a white powder that dissolves in water and has a light, almost chalky feel when dry. Chemists first explored aluminum salts for sweat control in the early 1900s, but the mix with zirconium and glycine was adopted later to improve performance and reduce skin irritation. Today manufacturers create it in controlled reactors where the base metals are combined with water then neutralized with glycine, filtered and spray-dried into a consistent powder.

You will most often see this ingredient in stick and roll-on antiperspirants, cream deodorants and some body lotions designed for high-sweat areas. It can also appear in foot sprays and underarm wipes where long-lasting odor and moisture control are important. Because it focuses on sweat and odor, it is rarely found in facial skincare or hair products.

Aluminum Zirconium Tetrachlorohydrex Gly’s Cosmetic Benefits/Uses

This ingredient is prized for doing more than just stopping sweat. Here is how it works in a formula:

  • Antiperspirant – forms tiny plugs in the sweat ducts which reduce the flow of perspiration so underarms stay drier for longer
  • Astringent – gently tightens skin surface proteins which helps minimize the sensation of wetness and gives a fresher feel
  • Deodorant – lowers the pH of underarm skin making it harder for odor-causing bacteria to thrive thereby cutting down on smell

Who Can Use Aluminum Zirconium Tetrachlorohydrex Gly

This ingredient works well for most skin types including normal, oily and combination skin because it sits on the surface and targets sweat ducts rather than soaking deep into the skin. Very dry or highly sensitive skin may find it a little too tightening which can lead to discomfort or a stinging feel, especially if the underarm area is freshly shaved or already irritated.

Aluminum Zirconium Tetrachlorohydrex Gly is sourced from minerals and the amino acid glycine, so it contains no animal-derived material. That makes it suitable for both vegans and vegetarians.

Over-the-counter antiperspirants that use this salt are generally viewed as safe for pregnant or breastfeeding women when used as directed. Still, this is not medical advice and anyone who is pregnant or nursing should discuss all personal care products with a healthcare professional to be extra sure.

The compound does not absorb light or make skin more reactive to the sun, so it is not linked to photosensitivity. One point to remember is that most products carrying it are designed only for intact skin; avoid using them on broken cuts or after heavy waxing where the skin barrier is compromised.

Potential Side Effects/Adverse Reactions

Reactions to topical Aluminum Zirconium Tetrachlorohydrex Gly differ from person to person. The issues listed below are possible yet uncommon when the ingredient is used properly and formulated within safety limits.

  • Mild skin irritation such as redness itch or stinging, especially on recently shaved or broken skin
  • Dry or tight feeling in the underarm area due to its astringent effect
  • Contact dermatitis in individuals with a specific allergy to aluminum or zirconium salts
  • Temporary white residue on clothing or skin which can cause fabric staining if not washed out

If any discomfort or rash develops stop using the product immediately and seek advice from a healthcare provider.

Comedogenic Rating

Rating: 0 / 5

Aluminum Zirconium Tetrachlorohydrex Gly is a water-soluble mineral salt that does not leave an oily film or trap debris in pores. Because it stays near the surface of the sweat duct openings and is easily washed away it is considered non-comedogenic.

It is therefore generally suitable for people who are prone to acne or breakouts.

Since the ingredient is mostly used in underarm products rather than facial skincare the risk of clogging facial pores is even lower.

Summary

Aluminum Zirconium Tetrachlorohydrex Gly serves three main roles: antiperspirant astringent and deodorant. It forms tiny gel plugs inside sweat ducts to slow perspiration tightens surface proteins to reduce the feeling of wetness and lowers skin pH so odor-causing bacteria struggle to thrive.

The salt is widely used in stick and roll-on antiperspirants though some brands opt for simpler aluminum compounds to save on cost. For products that promise maximum sweat control it remains a go-to choice in the mainstream market.

At the levels allowed in over-the-counter products it is considered safe with only occasional mild irritation reported. As with any new personal care item it is smart to perform a quick patch test to ensure your skin agrees with the formula.

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