Ambrosia Trifida Extract: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 23, 2025
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All information on this page is verified using The Personal Care Products Council's (PCPC) INCI database. Our ingredient analyses are based exclusively on PCPC's technical data to ensure accuracy and reliability.

What Is Ambrosia Trifida Extract?

Ambrosia Trifida Extract comes from the whole Ambrosia trifida plant, better known as giant ragweed. Growers harvest the stems, leaves and flowers, then steep or soak them in a mix of water and safe solvents. This pulls out a blend of natural compounds such as flavonoids, phenolic acids, small amounts of essential oils, proteins, carbohydrates and minerals. After filtering and concentrating the liquid, manufacturers dry or stabilize the solution to create a cosmetic grade extract.

The plant has long been viewed as a hardy weed in North America. Folk healers once brewed it for skin poultices, and scientists later confirmed that parts of the plant are rich in antioxidant molecules. Once that research became public in the early 2000s formulators began testing the extract in lotions and creams. Today you will most often find Ambrosia Trifida Extract in anti-aging serums, daily moisturizers, sheet masks and after-sun gels that aim to calm and shield the skin.

Ambrosia Trifida Extract’s Cosmetic Benefits/Uses

In skin care formulas Ambrosia Trifida Extract serves as an antioxidant. By neutralizing excess free radicals it helps limit the chain reactions that can lead to dullness, rough texture and the look of early aging. Its protective action supports the skin’s own barrier, keeping products fresher on the shelf and helping skin appear smoother and more resilient after use.

Who Can Use Ambrosia Trifida Extract

Thanks to its gentle antioxidant profile Ambrosia Trifida Extract is generally suitable for all skin types including normal, dry, oily, combination and even most sensitive skins. Because it is water soluble and non-oily it will not weigh down oily skin or clog pores, while its calming nature can help dry or reactive skin feel more comfortable. The only group that may need extra care are people with a known allergy to ragweed or other plants in the Asteraceae family, as cross reactions are possible.

The extract is plant derived and usually processed without any animal by-products which makes it appropriate for vegans and vegetarians. That said manufacturing standards can vary so those following a strict lifestyle may want to check brand policies on animal testing and cross contamination.

There is no research suggesting the ingredient poses a risk for pregnant or breastfeeding women when used topically. Still, data is limited and every pregnancy is unique so this information is not medical advice. Expectant or nursing mothers should run any skincare product past their doctor just to be safe.

Ambrosia Trifida Extract does not increase photosensitivity. It can be used morning or night but it does not replace sunscreen so daily SPF is still essential.

Potential Side Effects/Adverse Reactions

Side effects from topical Ambrosia Trifida Extract can vary from person to person. The points below cover potential issues yet they are unlikely to happen for most users when the ingredient is formulated and used correctly.

  • Allergic contact dermatitis in individuals sensitive to ragweed or related plants
  • Mild redness or itching shortly after application, usually temporary
  • Stinging or burning if applied to broken or highly compromised skin
  • Eye irritation if the product migrates into the eye area
  • Possible interaction with strong exfoliating acids leading to increased dryness

If you experience any of these effects stop using the product and seek advice from a qualified healthcare professional.

Comedogenic Rating

Rating: 0 / 5

Ambrosia Trifida Extract is almost entirely water based and contains negligible amounts of lipids or heavy waxes that might block pores. It sits lightly on the skin and rinses away cleanly in leave-on or rinse-off products, so the chance of pore congestion is extremely low. This makes it a comfortable choice for people who deal with acne or frequent breakouts.

Keep in mind that other ingredients in a finished formula, like rich oils or silicones, can still raise the overall comedogenic potential even if the extract itself is non-comedogenic.

Summary

Ambrosia Trifida Extract delivers antioxidant support that helps neutralize free radicals and maintain a healthy-looking skin barrier. By scavenging oxidative molecules it can soften the look of early aging and keep formulas stable on the shelf.

The extract is still a niche ingredient compared with staples like vitamin C or green tea but its plant origin and gentle nature have earned it a quiet following in clean beauty and K-beauty products.

Current research and real-world use suggest it is low risk for most skin types with the main caution being possible ragweed allergy. As with any new skincare ingredient it is smart to do a small patch test first to be sure your skin agrees with it.

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