What Is Amidinobenzyl Benzylsulfonyl D-Seryl Glycinamide Acetate?
Amidinobenzyl Benzylsulfonyl D-Seryl Glycinamide Acetate is a lab-crafted peptide derivative designed for skin care. It combines an amidinobenzyl group, a benzylsulfonyl group, and a short chain of amino acids capped with an acetate salt. Because its layout is too intricate to isolate from plants or animals, manufacturers rely on solid-phase peptide synthesis, a step-by-step method that links amino acids on a resin bed then adds the functional groups that give the molecule its skin-loving properties. The result is a white to off-white powder that dissolves easily in water-based cosmetic formulas.
The peptide category first gained attention in the late 1990s when researchers found that certain amino acid sequences could encourage skin to look smoother and firmer. Amidinobenzyl Benzylsulfonyl D-Seryl Glycinamide Acetate emerged from that wave of innovation as chemists fine-tuned sequences to support skin softness without irritation. It entered commercial use in the early 2010s and has since been adopted by premium and mass-market brands alike.
You will most often find this ingredient in leave-on products where continuous contact with the skin maximizes its conditioning effect. Typical placements include daily moisturizers, anti aging serums, eye creams, sleeping masks, post-shave balms, and sheet masks aimed at boosting suppleness and overall skin comfort.
Amidinobenzyl Benzylsulfonyl D-Seryl Glycinamide Acetate’s Cosmetic Benefits/Uses
In topical formulas this ingredient serves one primary purpose: skin conditioning. By binding water to the outer layer of the skin and smoothing tiny surface irregularities it helps the complexion feel softer appear more even and maintain a healthy moisture balance throughout the day.
Who Can Use Amidinobenzyl Benzylsulfonyl D-Seryl Glycinamide Acetate
Because this peptide focuses on hydrating and softening the surface of the skin, it tends to work well for dry, normal and combination skin types. Oily or acne-prone users usually tolerate it too, since it is lightweight and non-occlusive, though those who react poorly to any new peptide may prefer to start with a lower concentration product. Sensitive skin users appreciate its gentle profile, as it carries a low risk of stinging or redness.
The ingredient is produced entirely through laboratory synthesis without animal by-products, which makes it suitable for vegans and vegetarians.
No data point to harmful effects during pregnancy or while breastfeeding when the molecule is used topically at levels found in cosmetics. This is not medical advice, and anyone who is pregnant or nursing should always have a doctor review their skin care routine.
Amidinobenzyl Benzylsulfonyl D-Seryl Glycinamide Acetate does not increase photosensitivity and can be used morning or night with or without sunscreen. It layers well with most common actives, including vitamin C, niacinamide and retinoids, without causing instability in the formula.
Potential Side Effects/Adverse Reactions
Side effects and reactions to topical Amidinobenzyl Benzylsulfonyl D-Seryl Glycinamide Acetate vary from person to person. The points below outline potential issues that could occur, but most users will not experience them when the ingredient is formulated and used correctly.
- Mild redness or warmth immediately after application
- Temporary itching on very sensitive skin
- Rare allergic contact dermatitis characterized by swelling or persistent rash
- Interaction-related irritation when layered with highly acidic products in the same routine
If any of these reactions occur stop use and consult a qualified health professional.
Comedogenic Rating
Rating: 0 / 5. Amidinobenzyl Benzylsulfonyl D-Seryl Glycinamide Acetate is a small water-soluble peptide that rinses cleanly from the skin and does not form an oily film, so it is extremely unlikely to clog pores on its own. This makes it suitable for people who are prone to acne or frequent breakouts. As always the finished product’s overall formula can influence pore-clogging potential, so check the full ingredient list if congestion is a concern.
Summary
Amidinobenzyl Benzylsulfonyl D-Seryl Glycinamide Acetate is a lab-made peptide that conditions skin by binding water to the surface and smoothing small rough spots, helping the complexion feel soft look even and stay comfortably hydrated. It shows up most often in leave-on moisturizers, serums and masks, though it is still a niche ingredient compared with better-known peptides and humectants.
Current research and in-market use suggest it is very safe for topical application, with only low-level reports of minor irritation. When trying any new product containing this peptide it is wise to patch test first so you can confirm personal tolerance before applying it to a larger area.