Aminopropyl Zinc Polysilsesquioxane Chloride: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 23, 2025
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All information on this page is verified using The Personal Care Products Council's (PCPC) INCI database. Our ingredient analyses are based exclusively on PCPC's technical data to ensure accuracy and reliability.

What Is Aminopropyl Zinc Polysilsesquioxane Chloride?

Aminopropyl Zinc Polysilsesquioxane Chloride is a hybrid of silicone, zinc and a small amino group that is made by first hydrolyzing and condensing 3-aminopropyltriethoxysilane, then reacting the resulting silicone network with zinc chloride. The result is a lightweight, water-compatible polymer that can sit on skin without feeling greasy. The idea of blending silicone chemistry with helpful metals like zinc started in the early 2000s as formulators looked for ingredients that could hydrate while giving a smooth finish. Over the last decade this material has worked its way into everyday beauty items because it pairs the silky feel of silicones with the soothing touch of zinc.

The production process begins with liquid silane that is mixed with water and a mild acid. As the ethoxy groups split off, the silane molecules link into a cage-like structure called polysilsesquioxane. Zinc chloride is then added, bonding to the amino sites and locking the metal into the network. The finished polymer is filtered, washed and usually supplied as a clear solution or fine powder that disperses easily in both water-based and hybrid cream formulas.

You will most often find Aminopropyl Zinc Polysilsesquioxane Chloride in leave-on moisturizers, lightweight anti-aging serums, soothing face masks and daily lotions aimed at balancing oil and water on the skin. It is also used in after-shave balms, eye creams and certain hair styling products where a soft touch and gentle hydration are needed.

Aminopropyl Zinc Polysilsesquioxane Chloride’s Cosmetic Benefits/Uses

This ingredient brings a mix of hydration and skin-friendly conditioning to modern formulas

  • Humectant: Attracts water from the air and pulls it toward the upper layers of skin, helping maintain a plump, comfortable feel through the day
  • Skin conditioning: Forms a breathable, silky film that softens rough patches, reduces the look of fine lines and leaves skin feeling smooth without clogging pores

Who Can Use Aminopropyl Zinc Polysilsesquioxane Chloride

Because it is lightweight and water friendly this polymer suits most skin types including oily, combination, normal and even sensitive skin that reacts to heavy creams. Very dry skin may still need an extra occlusive layer like a rich balm since the ingredient pulls in water rather than sealing it in. It is not known to trigger breakouts so acne-prone users generally tolerate it well.

The compound is made through synthetic chemistry and contains no animal-derived material, making it acceptable for vegans and vegetarians.

Current safety data shows no specific risks for women who are pregnant or breastfeeding when the ingredient is used topically in cosmetic amounts. That said this is not medical advice and anyone who is pregnant or nursing should discuss any skincare product with a healthcare professional to be sure it fits their personal needs.

Aminopropyl Zinc Polysilsesquioxane Chloride does not increase the skin’s sensitivity to sunlight so there is no special photo-protection advice beyond the usual daily sunscreen.

Potential Side Effects/Adverse Reactions

Skin responses can vary from person to person. The points below list potential effects that might occur, but most users will not notice any problems when the ingredient is included at the levels allowed for cosmetics.

  • Mild redness or warmth on very sensitive skin
  • Temporary stinging if applied to freshly shaved or broken skin
  • Dryness or tightness if used without a richer moisturizer on very dry skin
  • Allergic contact dermatitis in rare cases of individual allergy to silicones or zinc compounds
  • Eye irritation if the product accidentally gets into the eyes

If any discomfort, swelling or persistent irritation occurs stop using the product and seek advice from a medical professional.

Comedogenic Rating

Aminopropyl Zinc Polysilsesquioxane Chloride scores a 1 out of 5 on the comedogenic scale. Its lightweight silicone-based film allows skin to breathe and rinses away without leaving heavy residue, while the water-loving amino and zinc parts discourage pore congestion.

This low score makes it a friendly option for acne-prone or breakout-prone skin.

Keep in mind that overall pore-clogging risk depends on the full formula, so rich oils or waxes paired with this polymer could alter the end result.

Summary

Aminopropyl Zinc Polysilsesquioxane Chloride acts mainly as a humectant and skin-conditioning agent. It pulls moisture toward the surface, then lays down a smooth breathable layer that softens rough spots and blurs fine lines without feeling greasy.

While not as famous as hyaluronic acid or dimethicone, its combination of slip, light feel and soothing zinc has earned it a quiet but growing presence in moisturizers, serums and calming masks.

Available safety data shows a low risk of irritation, allergy or photosensitivity. Even so, skin can be unpredictable so patch test any new product containing this ingredient to stay on the safe side.

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