Ammonium C12-16 Alkyl Sulfate: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 23, 2025
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All information on this page is verified using The Personal Care Products Council's (PCPC) INCI database. Our ingredient analyses are based exclusively on PCPC's technical data to ensure accuracy and reliability.

What Is Ammonium C12-16 Alkyl Sulfate?

Ammonium C12-16 Alkyl Sulfate is a surfactant, meaning it lowers the surface tension between oil and water so dirt can be lifted away. Chemically, it is an ammonium salt made from sulfuric acid and a mix of fatty alcohols that contain 12 to 16 carbon atoms, which are usually sourced from coconut oil or palm kernel oil. The ingredient first appeared in household cleaners in the 1930s when synthetic detergents began to replace traditional soaps. Its strong yet predictable cleaning power soon caught the eye of cosmetic chemists looking for mild but effective cleansers for skin and hair.

The production process starts with fatty alcohols that react with sulfur trioxide to form an alkyl sulfate. This intermediate is then neutralized with ammonium hydroxide, yielding the finished ingredient in either a paste or liquid form. Its balanced mix of chain lengths helps it work well in water of different hardness levels while keeping formulas easy to rinse.

Today you will most often spot Ammonium C12-16 Alkyl Sulfate in shampoos, body washes, liquid hand soaps, facial cleansers, bubble baths, and some cleansing wipes. It sometimes appears in exfoliating scrubs or clay masks where a bit of foam helps rinse away the product cleanly. Because it is water soluble and produces rich lather at low cost, brands favor it when they need dependable cleansing without a heavy feel.

Ammonium C12-16 Alkyl Sulfate’s Cosmetic Benefits/Uses

This ingredient brings practical performance to everyday wash-off products

  • Cleansing: Breaks up oil, sweat and product buildup so they can be rinsed away quickly. This leaves skin or hair feeling fresh without a filmy residue
  • Foaming: Creates a stable, creamy lather that helps spread the formula, improving user experience and ensuring even coverage during washing

Who Can Use Ammonium C12-16 Alkyl Sulfate

Most people with normal, oily or combination skin can use products that contain Ammonium C12-16 Alkyl Sulfate without issue. Those with very dry or easily irritated skin may find it a bit too cleansing, which could leave the skin feeling tight or itchy because it can strip natural oils if used in high amounts or left on too long.

The ingredient is usually sourced from coconut or palm kernel oil and contains no animal by-products, so it is suitable for vegans and vegetarians. If you avoid palm-derived ingredients for environmental reasons, you may want to check whether the brand uses certified sustainable palm oil.

Pregnant or breastfeeding women are not known to face extra risk from using this surfactant in rinse-off products, and it has a long history of use in everyday toiletries. That said, this is not medical advice so anyone who is pregnant or nursing should show the full product list to a doctor or midwife before adding a new item to their routine just to be sure.

Ammonium C12-16 Alkyl Sulfate does not cause photosensitivity, meaning it will not make skin more likely to burn in the sun. It is also safe to use alongside most common skincare actives such as vitamin C, niacinamide and retinoids.

Potential Side Effects/Adverse Reactions

Reactions to the topical use of Ammonium C12-16 Alkyl Sulfate vary from person to person. The points below cover potential side effects that could occur, but most users will not notice any problems when the ingredient is used at the levels normally found in cosmetic formulas.

  • Dryness or tightness, especially on already dry skin
  • Stinging or redness on sensitive or compromised skin
  • Mild itching after rinsing
  • Eye irritation if the product accidentally gets into the eyes
  • Allergic contact dermatitis in rare cases
  • Slight fading of artificial hair color when used in shampoos

If you notice any of these effects stop using the product and seek advice from a medical professional or pharmacist.

Comedogenic Rating

Rating: 1 / 5
Ammonium C12-16 Alkyl Sulfate is fully water soluble and rinses off easily so it does not sit on the skin long enough to clog pores. Its molecules are designed to grab oil then leave with the rinse water which keeps residue low. Because of this the likelihood of it provoking blackheads or pimples is minimal yet not entirely zero for extremely reactive skin which is why it earns a 1 rather than a perfect 0.

Suitable for acne-prone skin in most cases.

Very oily skin types often appreciate its thorough cleansing action while those with active breakouts should still pair it with gentle moisturizers to avoid over-drying which can trigger rebound oiliness.

Summary

Ammonium C12-16 Alkyl Sulfate serves mainly as a cleanser and foam booster. Its surfactant structure loosens oil dirt and product buildup then lifts them away with water while whipping air into a creamy lather that spreads shampoo or face wash evenly.

The ingredient is a workhorse in mass market shampoos body washes and hand soaps thanks to its reliable performance and budget friendly cost though boutique or sulfate-free brands may skip it in favor of milder alternatives.

Safety data show it is well tolerated in rinse-off products with dryness and mild irritation being the most common issues at high levels. Overall it is considered safe for everyday use but as with any new skincare item a quick patch test on the inner forearm helps catch rare sensitivities before you commit to full use.

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