Amp-Isostearoyl Hydrolyzed Soy Protein: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 23, 2025
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All information on this page is verified using The Personal Care Products Council's (PCPC) INCI database. Our ingredient analyses are based exclusively on PCPC's technical data to ensure accuracy and reliability.

What Is Amp-Isostearoyl Hydrolyzed Soy Protein?

Amp-Isostearoyl Hydrolyzed Soy Protein is a plant based ingredient created by taking soy protein, breaking it down into smaller parts called peptides, then attaching those peptides to a fatty acid known as isostearic acid. The final step neutralizes the mix with AMP, a mild alkaline agent, so the ingredient stays stable and easy to blend into water based formulas. This mix of protein pieces and fatty chains gives the material a balanced character that is both water friendly and oil friendly.

The idea of pairing proteins with fatty acids started gaining attention in the late 1990s as brands looked for gentler alternatives to animal collagen and harsh detergents. Soy, already popular for its rich amino acid profile, proved a good choice. Chemists learned that adding isostearic acid improved how the protein sticks to hair and skin while AMP adjusted the pH for everyday use. Since then the ingredient has appeared in a wide range of personal care products.

Today you will most often spot Amp-Isostearoyl Hydrolyzed Soy Protein in shampoos, conditioners, leave-in sprays, face cleansers, light moisturizers, sheet masks and styling creams. Its ability to clean without stripping makes it common in sulfate free washes, while the conditioning side shows up in products that promise soft hair or smooth skin.

Amp-Isostearoyl Hydrolyzed Soy Protein’s Cosmetic Benefits/Uses

This multitasking ingredient adds several helpful qualities to beauty formulas

  • Cleansing: Its balanced structure lifts away oil and dirt yet stays mild, so products can cleanse without leaving skin or hair feeling tight
  • Hair Conditioning: The soy peptides can bind to damaged areas along the hair shaft, helping reduce frizz and improve softness and shine
  • Skin Conditioning: On skin the small protein fragments form a light film that boosts moisture, adds a silky feel and may temporarily smooth fine lines
  • Emulsifying: Because it has both water loving and oil loving parts, it helps keep water and oil mixed, leading to stable, easy to use creams and lotions

Who Can Use Amp-Isostearoyl Hydrolyzed Soy Protein

This ingredient is generally well tolerated by all major skin types including dry, oily, combination and even sensitive skin because it is mild and has a balanced pH. People with a known soy allergy should avoid it since it is derived from soy protein and trace allergens could remain.

Amp-Isostearoyl Hydrolyzed Soy Protein is plant based and contains no animal derived components so it suits both vegans and vegetarians.

No research points to specific risks for pregnant or breastfeeding women when the ingredient is used topically in cosmetics, but this is not medical advice. Anyone who is expecting or nursing should show the product to a qualified healthcare provider before adding it to a routine just to be safe.

The ingredient does not increase photosensitivity and can be used day or night without making skin more prone to sunburn. It is also color safe for treated hair and works in both rinse off and leave on formulas.

Potential Side Effects/Adverse Reactions

Individual responses to topical ingredients vary. The following is a list of potential side effects that could occur even though most users will not experience them when the product is formulated and used correctly.

  • Allergic reaction itching rash or hives in people sensitive to soy or any other component of the formula
  • Contact dermatitis localized redness or irritation if skin is already compromised or extremely sensitive
  • Eye irritation stinging or watering if the product accidentally gets into the eyes especially in higher concentration rinse off items like shampoo
  • Product buildup a weighed down feel on very fine hair if the formula is rich and not rinsed thoroughly

If any discomfort swelling or persistent irritation occurs stop using the product and consult a healthcare professional.

Comedogenic Rating

Rating: 1/5 – Amp-Isostearoyl Hydrolyzed Soy Protein is largely water soluble and forms a light breathable film rather than an oily layer that could block pores. The attached isostearic acid is present in small amounts and is balanced by the peptide portion, resulting in a very low likelihood of clogging.

Because of this low rating it is generally suitable for people who are prone to acne or breakouts.

The final effect always depends on the full formula, so very heavy creams that include this ingredient along with rich oils may still feel occlusive on some skins.

Summary

Amp-Isostearoyl Hydrolyzed Soy Protein cleanses, conditions hair and skin, and stabilizes emulsions. Its protein fragments lift away dirt while the attached fatty chain helps them anchor to damaged spots, leaving hair softer and skin smoother. The dual water-and-oil affinity also lets it keep creams and lotions from separating.

It shows up in modern sulfate-free shampoos, lightweight conditioners and gentle facial cleansers, but it is not yet as common as classic surfactants so you may not see it on every shelf.

Topically it is considered low risk with minimal reports of irritation or pore clogging. As with any new cosmetic ingredient it is smart to try a small patch first to be sure your skin agrees with it.

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