Arctigenin: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 23, 2025
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All information on this page is verified using publicly available nomenclature standards and reference materials from The Personal Care Products Council (PCPC) and the European Commission's CosIng database. Our analyses are based on technical data from these sources to ensure accuracy and reliability.

What Is Arctigenin?

Arctigenin is a natural compound found mainly in the seeds and roots of burdock, a hardy plant that grows across Europe and Asia. Chemically it belongs to a group called lignans, plant molecules known for their ability to fight off damaging free radicals. First isolated by researchers studying traditional herbal remedies in the 1950s, arctigenin later caught the eye of cosmetic chemists looking for stable plant based antioxidants that work well on skin.

Most cosmetic grade arctigenin is made by gently extracting burdock with food grade alcohol or water, then purifying the liquid to collect the active molecule. The final powder is standardized so each batch delivers a consistent level of antioxidant activity and is easy to blend into creams or serums.

You will usually spot arctigenin in leave on products designed to protect or renew the skin such as anti aging creams, daily moisturizers, brightening serums, soothing masks, after sun lotions and targeted eye treatments. It is prized for being plant sourced, lightweight and compatible with common ingredients like hyaluronic acid or niacinamide.

Arctigenin’s Cosmetic Benefits/Uses

Arctigenin is added to skin care for one key reason: its strong antioxidant power. By neutralizing free radicals that come from UV light, pollution and everyday stress, it helps reduce the look of fine lines and dullness while supporting the skin’s natural barrier.

Who Can Use Arctigenin

Arctigenin suits most skin types including normal, dry, combination and oily because it is lightweight and non greasy. People with easily irritated or redness-prone skin often tolerate it well thanks to its calming antioxidant nature. There are no well known reasons to avoid it for any particular skin type, though anyone with a proven burdock allergy should steer clear.

The molecule is extracted from burdock, a plant, so it is naturally suitable for vegans and vegetarians as long as the finished product is not mixed with animal derived additives and has not been tested on animals.

Current research has not flagged topical arctigenin as a concern for pregnant or breastfeeding women, but studies are limited. This is not medical advice and anyone who is expecting or nursing should show the ingredient list of any product they plan to use to a qualified healthcare professional.

Arctigenin does not make skin more sensitive to sunlight so it is unlikely to increase the risk of sunburn. Regular sunscreen is still recommended because ultraviolet light creates the free radicals that antioxidants like arctigenin help neutralize.

Potential Side Effects/Adverse Reactions

Side effects and reactions to topical arctigenin can vary from person to person. The following is a list of potential effects only and most users will not experience them when the ingredient is formulated and used correctly.

  • Mild redness or stinging
  • Dry or tight feeling if applied in a product with high alcohol content
  • Allergic contact dermatitis in individuals sensitive to burdock or related plants
  • Interaction irritation if layered immediately with strong exfoliating acids or retinoids

If any of these effects occur stop using the product and seek guidance from a healthcare professional.

Comedogenic Rating

Rating: 0

Arctigenin is water or alcohol soluble rather than oily and is used at very low percentages, so it does not sit inside pores or create a film that traps dead cells. No data links it to blocked follicles or acne flare-ups, which is why it earns a non-comedogenic score.

Suitable for acne-prone and breakout-prone skin.

Because it is often paired with lightweight humectants and calming agents, the full formula is also unlikely to feel heavy or greasy, further supporting its low clogging potential.

Summary

Arctigenin is a plant derived antioxidant that mops up free radicals, calms visible redness and helps the skin barrier stay strong. It performs these jobs by donating electrons to unstable molecules, lowering the chain reaction of oxidative stress and soothing surface irritation.

Although not as famous as vitamin C or green tea, it is gaining quiet popularity in clean beauty lines and some Korean formulations thanks to its stability and gentle feel.

Current research and user reports show it is generally safe with a low risk of irritation, but whenever you try a new product it is smart to patch test first just to be sure your skin agrees.

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