Artemisia Annua Leaf/Stem Extract: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 23, 2025
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All information on this page is verified using publicly available nomenclature standards and reference materials from The Personal Care Products Council (PCPC) and the European Commission's CosIng database. Our analyses are based on technical data from these sources to ensure accuracy and reliability.

What Is Artemisia Annua Leaf/Stem Extract?

Artemisia Annua Leaf/Stem Extract comes from the leaves and stems of Artemisia annua, an aromatic herb in the daisy family. The plant is packed with helpful plant chemicals such as flavonoids, chlorogenic acids and the well-known compound artemisinin, all of which give it calming and conditioning properties when used on skin. Long valued in traditional herbal infusions, the plant drew modern interest in the 1970s for its active molecules, and beauty formulators soon explored its soothing potential for topical products.

To create the cosmetic-grade extract, freshly harvested leaves and stems are cleaned, dried and cut into small pieces. They are then steeped in a skin-friendly solvent like glycerin, propanediol or water to pull out the beneficial compounds. After filtration and concentration, the liquid extract is standardized and preserved so it stays stable once mixed into formulas.

You will most often spot Artemisia Annua Leaf/Stem Extract in calming face masks, hydrating toners, lightweight moisturizers, after-sun gels, anti-blemish spot treatments and gentle anti-aging serums. Its mild nature makes it a go-to for products aimed at sensitive or stressed skin.

Artemisia Annua Leaf/Stem Extract’s Cosmetic Benefits/Uses

The main role of Artemisia Annua Leaf/Stem Extract in skincare is skin conditioning. By supplying antioxidants and soothing phytochemicals it helps keep the surface of the skin soft, comfortable and balanced. Formulators add it to support the skin barrier, reduce the feel of irritation and leave a refreshed look and feel after use.

Who Can Use Artemisia Annua Leaf/Stem Extract

This extract is gentle enough for most skin types including dry, oily, combination and sensitive skin because it is primarily soothing and light in texture. Extremely reactive or allergy-prone skin should proceed with caution only if there is a known sensitivity to plants in the daisy family, since Artemisia annua belongs to that group.

Because the ingredient is entirely plant derived and no animal products or by-products are involved in its harvesting or processing, it is suitable for both vegans and vegetarians.

No specific warnings exist for pregnant or breastfeeding women when the extract is used topically in cosmetic amounts. That said, this is not medical advice and anyone who is pregnant or nursing should run any skincare product they use past a qualified doctor just to be safe.

Artemisia Annua Leaf/Stem Extract is not known to cause photosensitivity, so it will not make skin more prone to sunburn. Normal daily sun protection is still recommended for overall skin health.

Potential Side Effects/Adverse Reactions

Side effects and reactions to the topical use of Artemisia Annua Leaf/Stem Extract can vary from person to person. The points below outline potential issues that could arise, but they are uncommon when the ingredient is formulated and used correctly.

  • Redness or mild irritation
  • Itching or stinging on application
  • Dryness or tightness if the formula lacks additional hydrators
  • Allergic contact dermatitis in individuals sensitive to Artemisia or other members of the Asteraceae family such as ragweed
  • Cross-reaction with other strong actives in a routine leading to over-exfoliation or barrier disruption

If any of these reactions occur discontinue use immediately and consult a healthcare professional if symptoms persist or worsen.

Comedogenic Rating

Rating: 0

Artemisia Annua Leaf/Stem Extract is largely composed of water-soluble flavonoids, acids and other lightweight molecules with almost no oily residue, so it does not clog pores. Formulas that feature the extract usually rely on gel or fluid bases rather than heavy butters or waxes, which further keeps the risk of congestion low. This makes the ingredient suitable for people who are prone to acne or frequent breakouts.

Because the extract itself is non-pore-clogging, any comedogenic risk in a finished product will come from other ingredients such as rich emollients or thick occlusives, not from the Artemisia extract.

Summary

Artemisia Annua Leaf/Stem Extract works as a skin-conditioning agent that calms visible redness, supplies antioxidants and helps skin feel soft and balanced. Its mix of soothing flavonoids, chlorogenic acids and trace artemisinin moderates irritation and supports the skin barrier without adding heaviness.

The extract has enjoyed growing popularity in K-beauty and sensitive-skin formulas, though it is still less common than classic botanicals like aloe or chamomile. Brands that focus on gentle, plant-forward skincare are bringing it to wider attention.

Topically, the ingredient is regarded as very safe with a low likelihood of irritation when used in standard cosmetic concentrations. As with any new skincare product, it is wise to perform a quick patch test to confirm personal compatibility before applying it more broadly.

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