Ascorbic Acid/Orange/Citrus Limon/Citrus Aurantifolia Polypeptides: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 23, 2025
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All information on this page is verified using The Personal Care Products Council's (PCPC) INCI database. Our ingredient analyses are based exclusively on PCPC's technical data to ensure accuracy and reliability.

What Is Ascorbic Acid/Orange/Citrus Limon/Citrus Aurantifolia Polypeptides?

Ascorbic Acid/Orange/Citrus Limon/Citrus Aurantifolia Polypeptides is a hybrid ingredient that blends vitamin C with short chains of amino acids extracted from the dried, ground pulp of sweet orange, lemon and lime. Chemically, the process pairs ascorbic acid with fruit-derived polypeptides, forming a more stable complex than plain vitamin C. This stability helps protect the vitamin from rapid oxidation when exposed to light or air.

Formulators first explored fruit peptides in the 1990s as a way to boost the performance of antioxidant ingredients. By binding vitamin C to these naturally occurring peptides, they discovered a gentler, longer-lasting form that could sit comfortably in water-based creams and serums. Today the ingredient is produced by mixing purified ascorbic acid with the peptide-rich fruit pulp under controlled temperature and pH, then filtering and drying the finished complex into a fine powder ready for cosmetic use.

You will most often see Ascorbic Acid/Orange/Citrus Limon/Citrus Aurantifolia Polypeptides in brightening serums, anti-aging creams, daily moisturizers, sheet masks and eye treatments where a stable form of vitamin C is desired.

Ascorbic Acid/Orange/Citrus Limon/Citrus Aurantifolia Polypeptides’s Cosmetic Benefits/Uses

In skincare formulas this ingredient serves one primary purpose: skin conditioning. By delivering vitamin C alongside moisturizing peptides, it helps the skin feel soft and hydrated while supporting a more even, radiant tone.

Who Can Use Ascorbic Acid/Orange/Citrus Limon/Citrus Aurantifolia Polypeptides

This ingredient is generally suitable for normal, dry, combination and oily skin. Its peptide complex makes the vitamin C gentler than pure ascorbic acid so even many sensitive skin types tolerate it, though very reactive or compromised skin might still feel a mild tingling.

Because all components come from plant sources, it fits easily into vegan and vegetarian routines as long as the finished product does not include animal-derived additives elsewhere in the formula.

There is no evidence that topical use is harmful during pregnancy or while breastfeeding, but this is not medical advice. Anyone who is pregnant or nursing should check with a doctor before adding new skincare just to be safe.

The ingredient itself does not cause photosensitivity. In fact vitamin C can help neutralize free radicals triggered by UV light. That said daily sunscreen is still essential for overall skin health.

It plays well with most other actives but may lose potency when layered directly with high-alkaline products or formulas rich in copper peptides.

Potential Side Effects/Adverse Reactions

Side effects from topical Ascorbic Acid/Orange/Citrus Limon/Citrus Aurantifolia Polypeptides vary from person to person. The points below list potential reactions only. When properly formulated most users experience none of these issues.

  • Transient stinging or tingling, especially on freshly exfoliated skin
  • Redness or irritation in those with very sensitive skin
  • Dryness or slight flaking if used in high concentrations without adequate moisturization
  • Allergic contact dermatitis in rare cases
  • Yellowish staining of fabrics if product transfers before fully absorbed

If any discomfort or adverse change occurs stop use and consult a healthcare professional.

Comedogenic Rating

Rating: 1. Ascorbic Acid/Orange/Citrus Limon/Citrus Aurantifolia Polypeptides is water soluble and contains no heavy oils or waxes that typically clog pores. The peptide complex and vitamin C dissolve easily and rinse away without leaving a greasy film, so the risk of blocked pores is very low.

Acne-prone users can generally use this ingredient without worrying about new breakouts.

Keep in mind that the finished product’s overall pore-clogging potential depends on the full formula. If the serum or cream pairs this complex with rich plant butters or silicones, the comedogenicity could rise.

Summary

Ascorbic Acid/Orange/Citrus Limon/Citrus Aurantifolia Polypeptides conditions skin by coupling antioxidant vitamin C with moisturizing fruit peptides. This combo supports smoother texture, brighter tone and a healthy-feeling moisture barrier while resisting oxidation better than plain ascorbic acid.

Although not as famous as pure L-ascorbic acid or trendy derivatives like tetrahexyldecyl ascorbate, this hybrid is gaining traction in midrange and boutique skincare for its stability and gentle feel.

Current safety data show it is well tolerated for most skin types with only minor risk of irritation. As with any new cosmetic ingredient it is smart to patch test a small area first to rule out personal sensitivity.

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