Ascorbyl Cyclo Peg-6: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 23, 2025
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All information on this page is verified using publicly available nomenclature standards and reference materials from The Personal Care Products Council (PCPC) and the European Commission's CosIng database. Our analyses are based on technical data from these sources to ensure accuracy and reliability.

What Is Ascorbyl Cyclo Peg-6?

Ascorbyl Cyclo PEG-6 is a modified form of vitamin C in which the ascorbic acid core is linked to a short chain of six polyethylene glycol units. This connection makes the molecule more water friendly and more stable than plain vitamin C, qualities that help it mix smoothly into modern skin care formulas.

The ingredient is created through a controlled reaction between ascorbic acid and ethylene oxide, followed by purification to remove any unused raw materials. The finished powder or liquid is then ready for use by cosmetic chemists.

Interest in vitamin C alternatives began in the late 1990s when brands searched for stable antioxidants that would not brown or lose power in the jar. By attaching PEG units in a ring-like “cyclo” shape, researchers found they could slow down oxidation and give products a longer shelf life. Since then, Ascorbyl Cyclo PEG-6 has appeared in many leave-on and rinse-off formulas.

You will most often see it in brightening serums, daily moisturizers, anti aging creams, clay or sheet masks, gentle cleansers and lightweight eye treatments where a stable form of vitamin C is needed but strong acidity is not desired.

Ascorbyl Cyclo Peg-6’s Cosmetic Benefits/Uses

In skin care this ingredient acts as a chelating agent. By grabbing on to trace metals that sneak into a product during manufacturing or daily use, it stops those metals from triggering unwanted color changes or breaking down delicate actives. The result is a formula that stays clear, keeps its intended fragrance and delivers its benefits for a longer period on your bathroom shelf.

Who Can Use Ascorbyl Cyclo Peg-6

This ingredient is generally suitable for dry, oily, combination and normal skin because its pH is close to neutral and it lacks the sting that pure vitamin C can cause. Sensitive skin usually tolerates it as well, though anyone with a known allergy to polyethylene glycol or vitamin C derivatives should proceed with caution.

Ascorbyl Cyclo PEG-6 is made through a laboratory process that starts with plant based glucose and petroleum derived ethylene oxide and involves no animal sourced materials, so it is considered vegan and vegetarian friendly.

Current safety data show no specific risks for women who are pregnant or breastfeeding when the ingredient is used topically in cosmetic amounts. This is not medical advice and anyone who is expecting or nursing should review all skincare products with a qualified healthcare provider to be certain they fit their personal situation.

The molecule does not increase photosensitivity. In fact vitamin C relatives often provide a small supportive boost to daily sunscreen use, though they never replace it. No other special lifestyle adjustments are needed when incorporating this ingredient into a routine.

Potential Side Effects/Adverse Reactions

Responses to topical Ascorbyl Cyclo Peg-6 differ from one person to the next. The following points describe potential side effects that have been reported, but they are uncommon when the ingredient is used at the low levels typical of finished cosmetics.

  • Redness or mild stinging on application, most often in people with a disrupted skin barrier
  • Transient itching or warmth that resolves within minutes
  • Rare allergic contact dermatitis in individuals sensitive to PEG compounds or vitamin C derivatives
  • Eye irritation if the product is accidentally rubbed into the eyes

If any uncomfortable reaction develops discontinue use and seek advice from a healthcare professional.

Comedogenic Rating

Rating: 0 out of 5. Ascorbyl Cyclo PEG-6 is highly water soluble, contains no oily or waxy residues and does not linger within pores. Its primary role is to bind metal ions rather than coat the skin, so it has virtually no chance of clogging follicles. This makes it appropriate for those who are prone to acne or breakouts. Because it is a PEG-based molecule, it rinses away cleanly and is unlikely to contribute to surface congestion. No published data link it to the formation of blackheads or whiteheads.

Summary

Ascorbyl Cyclo PEG-6 is a stabilized vitamin C derivative that mainly serves as a chelating agent, latching onto stray metal ions to keep formulas clear, fresh and effective. By preventing metals from kick-starting oxidation it quietly supports the longevity of other active ingredients and helps preserve color and scent.

The ingredient enjoys a modest presence in skin care, appearing in select serums, moisturizers and masks when brands want vitamin C benefits without the instability of pure ascorbic acid. It is not as famous as ascorbyl glucoside or tetrahexyldecyl ascorbate but formulators value its reliability.

Current research and cosmetic use levels point to a strong safety profile with very low irritation potential for most skin types, including sensitive and acne prone. As with any new product, a simple patch test on the inner arm or behind the ear is a smart precaution before full-face application.

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