Benzisothiazolinone: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 23, 2025
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All information on this page is verified using The Personal Care Products Council's (PCPC) INCI database. Our ingredient analyses are based exclusively on PCPC's technical data to ensure accuracy and reliability.

What Is Benzisothiazolinone?

Benzisothiazolinone, often shortened to BIT, is a synthetic preservative whose scientific name is 1,2-Benzisothiazol-3(2H)-one. Chemically, it belongs to the isothiazolinone family, a group of compounds known for keeping unwanted microbes at bay. BIT was first introduced to household and industrial products in the 1970s as an alternative to older preservatives that had fallen out of favor. Over time, formulators noticed its strong ability to stop bacteria and fungi from growing, so it eventually found its way into personal care items.

Making BIT starts with reacting o-aminothiophenol with simple carbonyl compounds in controlled factory settings. The process forms a ring structure that gives the molecule its antimicrobial punch. Because it is produced in a lab, it offers reliable purity and performance for manufacturers who need tight quality standards.

Today Benzisothiazolinone shows up in a variety of rinse-off and leave-on products. You may spot it in face masks, liquid foundations, sunscreens, shampoos, conditioners, body lotions, wet wipes and even certain styling gels. Brands choose it when they want to protect water-based formulas without relying on older preservative systems.

Benzisothiazolinone’s Cosmetic Benefits/Uses

Benzisothiazolinone serves a single but important purpose in cosmetics: it is an antimicrobial agent. By stopping bacteria, mold and yeast from multiplying, BIT helps keep products fresh and safe for use throughout their shelf life. This protection is particularly valuable in formulas that contain a lot of water, such as lotions, shampoos and creams, where microbes would otherwise thrive.

Who Can Use Benzisothiazolinone

Benzisothiazolinone is generally considered suitable for normal, oily and combination skin because it is used at very low levels that do not affect skin feel or oil balance. People with very sensitive or already irritated skin may want to proceed with caution since preservatives can sometimes aggravate existing issues.

The ingredient is fully synthetic and does not rely on any animal derived raw materials, so it is acceptable for both vegans and vegetarians. Its manufacture also does not require animal by-products.

Current safety reviews have not flagged special concerns for women who are pregnant or breastfeeding when the preservative is present at the low levels allowed in cosmetics. Still, this is not medical advice and anyone who is pregnant or nursing should ask a healthcare professional before introducing new products just to be safe.

Benzisothiazolinone does not make skin more sensitive to sunlight and it is chemically stable under UV exposure. It is mainly found in water based formulas and is less common in products meant for the eye area where delicate tissue could react more easily.

Potential Side Effects/Adverse Reactions

Responses to topical Benzisothiazolinone vary from person to person. The points below outline possible side effects but most users will not experience them when the ingredient is used at the correct level in a well-formulated product.

  • Contact dermatitis – redness itching or burning at the site of application
  • Allergic sensitization – delayed eczematous reaction that can appear after repeated exposure
  • Eye irritation – stinging or watering if the product accidentally enters the eyes
  • Cross reaction with other isothiazolinones – people already sensitized to related preservatives like methylisothiazolinone may react to BIT as well
  • Dryness or mild stinging – rare transient feeling in very dry or compromised skin

If any of these reactions occur stop using the product and consult a healthcare professional.

Comedogenic Rating

Rating: 0/5 – Benzisothiazolinone is water soluble, used at very low concentrations and has no oily or waxy components that could block pores. Because it stays dissolved in the water phase of a formula it is rinsed or absorbed without leaving residue that might trap sebum or dead cells.

Suitable for acne prone or breakout prone skin.

No studies link BIT to increased comedones, and it is not chemically related to ingredients that commonly cause clogged pores.

Summary

Benzisothiazolinone is an antimicrobial preservative that keeps cosmetics free of bacteria, mold and yeast by disrupting microbial cell membranes. It is effective in tiny amounts which lets formulators protect water rich products without adding heavy or greasy materials.

The ingredient is more common in household cleaners than in personal care, but it still shows up in some modern lotions, sunscreens and hair products when brands need a strong broad spectrum preservative.

Regulatory reviews find it safe at the low levels allowed in cosmetics, though people with very sensitive skin may react. As with any new skincare product it is smart to perform a quick patch test before full use.

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