Benzophenone-6: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 23, 2025
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All information on this page is verified using The Personal Care Products Council's (PCPC) INCI database. Our ingredient analyses are based exclusively on PCPC's technical data to ensure accuracy and reliability.

What Is Benzophenone-6?

Benzophenone-6, also known as 2,2′-Dihydroxy-4,4′-dimethoxybenzophenone, is a lab-made compound that belongs to the benzophenone family. These molecules are valued for their ability to soak up parts of the ultraviolet (UV) light spectrum. Chemists first explored benzophenones in the mid-20th century when the demand for better sun protection and color-stable products started to rise. Over time Benzophenone-6 became one of the go-to choices because it offers strong UV protection while staying clear and stable in formulas.

The ingredient is produced through a controlled chemical reaction that links two hydroxy-methoxy benzene rings with a carbonyl group in the middle. The process happens in large stainless-steel reactors under precise temperature and pH settings to keep impurities low. Once purified the pale yellow powder is milled into a fine grade so it blends smoothly into creams, gels or sprays.

You will most often find Benzophenone-6 in facial moisturizers with SPF, daily wear sunscreens, leave-on conditioners, color-safe hair sprays, lip balms, nail polishes and fragrance mists. Its clear finish lets brands add UV protection without changing the look or feel of bright colors or light textures.

Benzophenone-6’s Cosmetic Benefits/Uses

This ingredient brings more than one useful role to a formula

  • Fragrance: Acts as a scent fixative that slows down the evaporation of perfume oils so the product’s aroma lasts longer on the skin or hair
  • UV absorber: Screens out both UVA and UVB rays which helps protect skin surface cells from sun damage and keeps dyes fragrances and other delicate ingredients from breaking down in light

Who Can Use Benzophenone-6

Benzophenone-6 is generally suitable for most skin types, including normal, dry, oily and combination skin. Its lightweight non-occlusive nature means it rarely clogs pores or leaves a greasy feel. People with very sensitive or eczema-prone skin may want to proceed with caution because any chemical UV filter, even well tolerated ones, can occasionally trigger redness or stinging in reactive complexions.

The ingredient is fully synthetic and contains no animal-derived substances, making it appropriate for both vegetarians and vegans. Most major suppliers also certify that no animal testing is performed on the raw material in regions where that is legally possible, further supporting cruelty-free claims.

Current safety assessments indicate that topical Benzophenone-6 is unlikely to pose a risk during pregnancy or while breastfeeding when used in concentrations allowed for cosmetics. That said this is not medical advice and anyone who is pregnant or nursing should show the full ingredient list of any product they plan to use to their doctor for personalized guidance.

Benzophenone-6 does not cause photosensitivity; in fact its primary job is to absorb UV light and help guard against sun damage. Because it is photo-stable it will not break down quickly in sunlight or create free radicals at normal cosmetic levels.

Potential Side Effects/Adverse Reactions

Reactions to topical Benzophenone-6 differ from person to person. The points below outline potential side effects yet they are uncommon for most users when the ingredient is used at approved levels in properly formulated products.

  • Transient stinging or mild burning on very sensitive or compromised skin
  • Redness or rash due to allergic contact dermatitis
  • Photoallergic reaction in rare cases where the ingredient plus sunlight triggers an immune response
  • Eye irritation if the product accidentally gets into the eyes
  • Potential interaction with certain prescription topical medications leading to increased sensitivity

If any persistent irritation or other adverse effect occurs stop using the product and consult a qualified healthcare professional.

Comedogenic Rating

Rating: 1 / 5 (very low)

Benzophenone-6 has a small molecular size and sits lightly on the skin so it does not create the heavy, occlusive film that often plugs pores. It is used in sunscreens made for oily or breakout-prone skin which further supports the low rating. For most people who struggle with acne this filter is unlikely to fuel new spots, though the full product formula always matters.

Because it stays photo-stable and does not oxidize easily it is less likely to form pore-clogging by-products over time.

Suitable for acne-prone users: Yes, in most cases.

Summary

Benzophenone-6 works mainly as a UV absorber and a fragrance fixative. Its ring-shaped structure captures parts of UVA and UVB light, changing that energy into a harmless low-level heat that drifts away from the skin. The same structure slows down the evaporation of perfume oils, keeping a product’s scent noticeable for longer.

While not as famous as ingredients like oxybenzone or avobenzone, Benzophenone-6 shows up in many modern formulas that aim for clear textures and stable color, especially in leave-on hair care, lip balms and lightweight facial SPFs.

Current safety reviews find it well tolerated at approved levels with only rare reports of irritation or allergy. As with any cosmetic ingredient it is smart to do a quick patch test the first time you try a product so you can spot any personal sensitivity early.

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