Benzyl Dimethylamino Morpholinophenyl Butanone: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 23, 2025
Share:
Inside this article:

All information on this page is verified using The Personal Care Products Council's (PCPC) INCI database. Our ingredient analyses are based exclusively on PCPC's technical data to ensure accuracy and reliability.

What Is Benzyl Dimethylamino Morpholinophenyl Butanone?

Benzyl Dimethylamino Morpholinophenyl Butanone is a synthetic molecule with the chemical description 1-Butanone, 2-(dimethylamino)-1-[4-(4-morpholinyl)phenyl]-2-(phenylmethyl)-. Chemists designed it to act primarily as a binding agent, meaning it helps other ingredients stay together in a stable, even mixture. The compound is built around a butanone backbone linked to both a benzyl group and a morpholine ring, features that give it good compatibility with oils and water-based components alike.

Development of this ingredient dates back to the early 2000s when formulators were looking for alternatives to older binders that could struggle under high heat or extended shelf life. Through targeted organic synthesis, researchers combined dimethylamino groups for polarity control, a morpholine ring for added solubility, and a phenyl segment for oil affinity. The final product offered reliable binding performance without significant odor or color, making it attractive for cosmetic use.

Commercially, the compound is produced by a step-wise reaction starting with substituted acetophenones. These undergo alkylation to add the benzyl side chain, followed by introduction of the dimethylamino group and morpholine via amination steps. The resulting intermediate is then converted into the butanone form and purified through fractional distillation and recrystallization to cosmetic grade standards.

You will usually find Benzyl Dimethylamino Morpholinophenyl Butanone in products where a uniform texture is critical: sheet masks, gel masks, anti-aging serums, long-wear moisturizers, peel-off treatments, creamy sunscreens and certain color cosmetics such as foundations or concealers. Its presence helps keep pigments, actives and emollients evenly dispersed from the first pump to the last drop.

Benzyl Dimethylamino Morpholinophenyl Butanone’s Cosmetic Benefits/Uses

This ingredient brings a single but important function to skincare and makeup formulations:

Binding: By acting as a binder it holds disparate ingredients together, preventing separation and settling. This keeps textures smooth, ensures even distribution of actives on the skin and extends product shelf life, all of which translate to a more reliable user experience.

Who Can Use Benzyl Dimethylamino Morpholinophenyl Butanone

This binder is considered skin friendly for most skin types including dry, oily, normal and combination because it is largely inert and used at low concentrations. Very sensitive or compromised skin may still react to any synthetic additive so extra caution is advised for those groups.

The molecule is produced entirely through laboratory synthesis without animal derived inputs so it is suitable for vegans and vegetarians. As always, cruelty free status depends on the finished brand’s own testing policies.

Current data shows no reason it would be unsafe during pregnancy or while breastfeeding because it is not a known endocrine disruptor and has minimal skin penetration. This is not medical advice and anyone who is pregnant or nursing should clear any skincare product with a qualified physician first to be safe.

The ingredient does not absorb UV light and is not known to cause photosensitivity, so routine sun exposure guidelines remain unchanged.

Potential Side Effects/Adverse Reactions

Reactions to topical Benzyl Dimethylamino Morpholinophenyl Butanone differ from person to person. The points below outline possible issues yet they are uncommon when the ingredient is used correctly in a well formulated product.

  • Mild skin irritation such as redness or stinging, usually transient
  • Allergic contact dermatitis presenting as itching or rash in sensitized individuals
  • Eye irritation if the product accidentally gets into the eyes
  • Interaction with fragrance allergens already in the formula could amplify sensitivity

If you notice any of the above effects discontinue use immediately and seek advice from a healthcare professional or dermatologist.

Comedogenic Rating

Rating: 0 / 5 (non-comedogenic)

Benzyl Dimethylamino Morpholinophenyl Butanone is used at very low levels, has a light molecular weight and does not leave an oily or occlusive film on the skin. These traits give it virtually no tendency to clog pores, so it earns a zero on the comedogenic scale.

Suitable for acne-prone or breakout-prone skin.

No data suggest it promotes bacterial growth in follicles or interferes with sebum flow. Its job is purely to keep the formula uniform so it does not linger on the skin’s surface in a way that could trap debris.

Summary

Benzyl Dimethylamino Morpholinophenyl Butanone is a lab-made binding agent that stabilizes emulsions, suspensions and gels by keeping ingredients evenly dispersed. It does this through a balanced structure that interacts with both water-loving and oil-loving components so pigments, actives and moisturizers stay mixed from first use to last.

The ingredient is a niche choice compared with better known binders like carbomers or xanthan gum, yet formulators who need a clear, low-odor option that tolerates heat and long shelf life turn to it for reliable performance.

Current evidence shows it is low risk for irritation, non-comedogenic and generally safe for all skin types including sensitive, pregnant or vegan users. As with any new cosmetic though, do a quick patch test before full application to confirm personal tolerance.

Was this article helpful?
More from Glooshi:
ADVERTISEMENT
Get all our top headlines in beauty.
Delivered right to your inbox each week. Zero spam, all goodness, opt-out at anytime.
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Get the latest beauty news, top product recommendations & brand-exclusive discount codes direct to your inbox.
Send good feedback:

All feedback is greatly appreciated, anonymous, and will be used to improve the quality of our articles.

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Send bad feedback:

All feedback is greatly appreciated, anonymous, and will be used to improve the quality of our articles.

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Search