What Is Benzylsulfonylserylglycine Amidinobenzamide Acetate?
Benzylsulfonylserylglycine Amidinobenzamide Acetate is a lab crafted peptide-like molecule designed to care for skin. It combines small building blocks called amino acids with a benzylsulfonyl group and an acetate salt to improve stability and ease of use in formulas. Scientists began exploring versions of this compound in the early 2000s while searching for gentler conditioning agents that mimic the skin’s own proteins. Large-scale production starts with plant derived sugars that are fermented to create amino acid units. These units are linked together in a controlled reaction vessel, then treated with benzylsulfonyl and amidino groups before being neutralized with acetic acid to form the final powder. The ingredient dissolves well in water, stays active over a wide pH range and has a mild scent, making it popular in lightweight gels, sheet masks, anti-aging serums, daily moisturizers, eye creams and after-sun lotions.
Benzylsulfonylserylglycine Amidinobenzamide Acetate’s Cosmetic Benefits/Uses
This ingredient is prized for its ability to improve the feel and look of skin.
As a skin conditioning agent it helps bind moisture to the surface, softens rough patches and gives formulas a silky glide. Regular use can leave skin looking smoother and more supple which is why brands often place it in products aimed at boosting hydration and supporting a healthy barrier.
Who Can Use Benzylsulfonylserylglycine Amidinobenzamide Acetate
This lightweight hydrating agent works well for nearly every skin type. Dry and mature skin benefit from the added moisture while oily and combination skin appreciate its non greasy feel. Sensitive skin typically tolerates it because it is fragrance free and low in irritants. There are no known issues for darker skin tones or acne-prone skin.
The molecule is synthesized from plant sugars in a fermenter so no animal derived materials are involved, making it suitable for vegans and vegetarians. Always confirm the finished product has the same cruelty-free standards.
No specific warnings exist for women who are pregnant or breastfeeding but comprehensive studies are limited. This content is not medical advice so anyone expecting or nursing should check with a healthcare professional before adding new products.
Benzylsulfonylserylglycine Amidinobenzamide Acetate does not increase photosensitivity. It also plays nicely with common actives such as retinol, niacinamide and exfoliating acids thanks to its broad pH stability.
Potential Side Effects/Adverse Reactions
Reactions to topical Benzylsulfonylserylglycine Amidinobenzamide Acetate differ from person to person. The following is a list of potential side effects only and most users will not experience them when the ingredient is formulated and used correctly.
- Mild redness or warmth at the application site
- Temporary itching or tingling
- Rare allergic contact dermatitis presenting as a rash or swelling
- Eye irritation if the product accidentally gets into the eyes
If any of these effects occur stop using the product and consult a medical professional.
Comedogenic Rating
Rating: 0 (non-comedogenic). Benzylsulfonylserylglycine Amidinobenzamide Acetate is a small, water-soluble molecule that does not leave an oily film so it will not clog pores. Its ability to sit lightly on the skin and rinse away easily keeps it from trapping dead cells or excess sebum. Therefore the ingredient is generally safe for people who are prone to acne or breakouts. At typical use levels it will not interfere with other non-comedogenic formulas or active treatments.
Summary
Benzylsulfonylserylglycine Amidinobenzamide Acetate is a lab crafted peptide-like compound that conditions skin by binding moisture to the surface, smoothing texture and supporting a healthy barrier. Its water-friendly structure helps formulas feel light while still delivering softness and suppleness. Although effective, the ingredient is still considered niche and is not as widespread as big names like hyaluronic acid or glycerin, but it is gaining traction in premium serums and masks.
Safety data show a low risk of irritation, no evidence of pore clogging and no animal-derived components, making it suitable for most users including vegans. As with any new skincare ingredient it is wise to perform a quick patch test when trying a product that contains it, especially if you have very sensitive or reactive skin.