Beta-Alanyl Hydroxyprolyldiaminobutyroyl Benzylamide: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 23, 2025
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All information on this page is verified using The Personal Care Products Council's (PCPC) INCI database. Our ingredient analyses are based exclusively on PCPC's technical data to ensure accuracy and reliability.

What Is Beta-Alanyl Hydroxyprolyldiaminobutyroyl Benzylamide?

Beta-Alanyl Hydroxyprolyldiaminobutyroyl Benzylamide is a lab designed peptide made by linking several small amino acids, including beta alanine and hydroxyproline, to a benzylamide group. Because it is synthesized in controlled factory settings rather than extracted from plants or animals, the ingredient can be produced with high purity and consistency. Developers first explored this peptide when looking for gentle alternatives to traditional firming agents and it began appearing in premium skin care lines in the late 2000s. Production usually starts with fermented amino acids that are carefully combined through step by step peptide bonding, purified, then dried into a fine powder for easy blending into creams or serums. You will most often see it in leave-on products such as anti aging moisturizers, targeted wrinkle treatments, sheet masks and eye creams where lasting surface contact is desired.

Beta-Alanyl Hydroxyprolyldiaminobutyroyl Benzylamide’s Cosmetic Benefits/Uses

This ingredient is valued for one key role that supports smoother looking skin.

Skin conditioning: By binding water and helping reinforce the skin’s natural barrier, the peptide leaves the surface feeling softer and more supple. Regular use can improve the look of fine lines and give the complexion a plumper fresher appearance.

Who Can Use Beta-Alanyl Hydroxyprolyldiaminobutyroyl Benzylamide

This lab made peptide is generally suitable for all skin types including dry, normal, combination and oily skin because it focuses on supporting the skin’s water balance rather than adding heavy oils or strong actives that might clog pores or cause peeling. Sensitive skin users usually tolerate it well thanks to its gentle nature though anyone highly reactive to peptides should proceed with caution.

Because the ingredient is synthesized entirely from fermented amino acids in a controlled setting it contains no animal derived components, making it appropriate for both vegans and vegetarians.

Current safety data shows no specific concerns for pregnant or breastfeeding women when the peptide is used topically in standard cosmetic concentrations. Still this is not medical advice and those who are pregnant or nursing should run any skincare product by their doctor just to be on the safe side.

The peptide does not make skin more reactive to sunlight and therefore does not cause photosensitivity. Normal daily sun protection is still encouraged for overall skin health.

Potential Side Effects/Adverse Reactions

Side effects and reactions to the topical application of Beta-Alanyl Hydroxyprolyldiaminobutyroyl Benzylamide can vary from person to person. The following is a list of potential side effects that are possible yet uncommon when the ingredient is formulated and used correctly.

  • Temporary redness or warmth – mild flushing that usually subsides shortly after application
  • Itching or tingling – light sensation that may occur as the product absorbs
  • Dry patches – rare in users who are already prone to dehydration
  • Swelling or puffiness – uncommon and typically limited to very sensitive areas such as around the eyes
  • Allergic contact dermatitis – extremely rare immune reaction leading to rash or persistent irritation

If you experience any negative effect discontinue use and consult a qualified healthcare professional.

Comedogenic Rating

Rating: 0. Beta-Alanyl Hydroxyprolyldiaminobutyroyl Benzylamide is a small, water-soluble peptide that contains no oils or waxes that could block pores. It sits on the skin surface, binds moisture then rinses away with normal cleansing so it does not leave behind residue that can mix with sebum. For these reasons it is considered non-comedogenic and is suitable for people who are prone to acne or frequent breakouts. Because it relies on amino acid chemistry rather than heavy emollients, even higher concentrations used in targeted serums show no pore-clogging risk in available testing.

Summary

Beta-Alanyl Hydroxyprolyldiaminobutyroyl Benzylamide is a lab-crafted peptide that conditions skin by attracting water and helping strengthen the surface barrier, leading to a softer, plumper look with fewer visible fine lines. It performs these functions thanks to its chain of amino acids that mimic skin’s own building blocks, allowing it to slot neatly into topical formulas and boost hydration levels without heaviness.

Although it is not as famous as blockbuster ingredients like hyaluronic acid or retinol, its gentle profile has earned it a steady following in premium eye creams masks and lightweight anti-aging serums where a boost of smoothness is desired without irritation.

Current research shows it is safe for routine use across all skin types with very low risk of adverse effects. As with any new skincare ingredient performing a small patch test when you try a product containing this peptide is a smart way to confirm personal compatibility.

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