Bis-Aminoethoxyethane/Guanidine Hcl Copolymer: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 23, 2025
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All information on this page is verified using publicly available nomenclature standards and reference materials from The Personal Care Products Council (PCPC) and the European Commission's CosIng database. Our analyses are based on technical data from these sources to ensure accuracy and reliability.

What Is Bis-Aminoethoxyethane/Guanidine Hcl Copolymer?

Bis-Aminoethoxyethane/Guanidine Hcl Copolymer is a lab-made ingredient created by linking two small molecules, 1,2-bis-(2-aminoethoxy)ethane and guanidine hydrochloride, into a long repeating chain. The result is a water-friendly polymer that carries a gentle positive charge, which helps it interact with the slightly negative surface of many microbes. Chemists first explored the material for medical dressings, then cosmetic scientists noticed its ability to keep creams and lotions fresh without harsh preservatives. Production happens in closed reactors where the two building blocks are heated together with a catalyst, washed and filtered, then dried into a fine powder or concentrated solution. You will most often see it in leave-on products such as lightweight moisturizers, anti-aging serums, sheet masks, eye gels, scalp treatments and micellar waters, as well as in rinse-off cleansers and body washes that aim for a low-irritation formula.

Bis-Aminoethoxyethane/Guanidine Hcl Copolymer’s Cosmetic Benefits/Uses

This ingredient serves a single yet important role in personal care products.

As an antimicrobial it limits the growth of bacteria, yeast and mold inside the jar or bottle. This helps extend shelf life, keeps textures and scents stable and lowers the chance that a contaminated product will upset the skin. Because it works at low levels and is mild on its own, formulators can often reduce stronger preservatives, making the end product friendlier for sensitive skin.

Who Can Use Bis-Aminoethoxyethane/Guanidine Hcl Copolymer

Because it is mild and water soluble, this antimicrobial fits well with nearly every skin type, including normal, oily, dry, combination and sensitive skin. It does not leave a heavy residue or clog pores, so acne-prone users usually tolerate it too.

The ingredient is made entirely from synthetic building blocks, so it contains no animal derived raw materials and is generally considered suitable for vegans and vegetarians. Manufacturers often highlight cruelty-free processing but it is still wise to check that the finished product carries the appropriate certification.

Current safety data show no special hazards for women who are pregnant or breastfeeding when the polymer is used at the low levels found in cosmetics. This is not medical advice, and anyone who is expecting or nursing should have a quick chat with a healthcare professional before adding new products to a routine.

Bis-Aminoethoxyethane/Guanidine Hcl Copolymer is not known to cause photosensitivity, so it will not make skin more reactive to the sun. Standard daytime SPF use is still recommended to protect overall skin health.

Potential Side Effects/Adverse Reactions

Responses to topical Bis-Aminoethoxyethane/Guanidine Hcl Copolymer can vary from person to person. The effects listed below are possibilities, not probabilities. When used at appropriate concentrations most people notice no problems at all.

  • Mild stinging or burning on very compromised or freshly exfoliated skin
  • Temporary redness or warmth shortly after application
  • Dryness if the formula lacks adequate humectants or emollients
  • Eye irritation if the product accidentally gets into the eyes
  • Rare allergic contact dermatitis in individuals sensitive to guanidine derivatives

If any unwanted reaction occurs stop using the product and consult a qualified healthcare professional for guidance.

Comedogenic Rating

Rating: 0 out of 5

Bis-Aminoethoxyethane/Guanidine Hcl Copolymer is completely water soluble and used at very low levels so it does not linger on the skin or mix with sebum. It contains no oils waxes or fatty acids that can block pores which is why it earns the lowest score.

The ingredient is considered safe for people who are prone to acne or breakouts.

No evidence shows it aggravates fungal acne and it rinses off easily in cleanser formats further reducing any clogging risk.

Summary

Bis-Aminoethoxyethane/Guanidine Hcl Copolymer works as an antimicrobial that keeps creams cleansers serums and masks free from bacteria yeast and mold. Its gentle positive charge binds to microbe cell walls disrupting their growth so formulas stay fresh with fewer harsh preservatives.

The polymer is still a niche choice but its mild nature is winning fans among formulators focused on sensitive skin options.

Available data point to a strong safety record with low irritation potential. Even so it is wise to perform a simple patch test when trying a product that contains this ingredient just to stay on the safe side.

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