Bis-Ethoxydiglycol Succinate: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 23, 2025
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All information on this page is verified using The Personal Care Products Council's (PCPC) INCI database. Our ingredient analyses are based exclusively on PCPC's technical data to ensure accuracy and reliability.

What Is Bis-Ethoxydiglycol Succinate?

Bis-Ethoxydiglycol Succinate is a lab-made liquid derived from combining ethoxydiglycol, a lightweight glycol, with succinic acid, a naturally occurring acid found in sugarcane and some fruits. The result is a clear, odorless fluid that dissolves easily in water and many oils, giving formulators a flexible ingredient that slips into both gel and cream textures without changing their feel.

Chemists first explored this molecule in the early 2000s while searching for gentler alternatives to heavy glycols and sticky humectants. By attaching succinate groups to ethoxydiglycol, they discovered a compound that attracts water, feels silky on skin and helps dissolve stubborn active ingredients. Once its stability and skin friendliness were confirmed through standard safety testing, it quickly earned a spot on ingredient lists for modern skincare.

Production starts with plant-sourced ethoxydiglycol and bio-based succinic acid. Under controlled heat and vacuum, the two react in the presence of a mild catalyst, forming ester bonds and yielding Bis-Ethoxydiglycol Succinate. After purification and quality checks, the finished material is shipped as a low-viscosity liquid ready for blending.

You’ll most often see it in hydrating serums, lightweight lotions, sheet mask essences, mist toners, after-sun gels, anti-aging creams and makeup primers where a smooth, non-greasy finish is important. Because it works well with both water-soluble and oil-soluble ingredients, formulators also use it in concentrated treatment drops and exfoliating solutions.

Bis-Ethoxydiglycol Succinate’s Cosmetic Benefits/Uses

This multitasker brings several perks to a formula

  • Humectant – attracts water from the environment and draws it into the upper layers of skin helping to keep skin plump, comfortable and less prone to flakiness
  • Skin Conditioning – leaves a light, silky film that makes skin feel softer and smoother without heaviness which is especially helpful in oil-free or quick-absorbing products
  • Solvent – dissolves difficult actives such as certain antioxidants or exfoliating acids ensuring the finished product remains clear, stable and easy to spread

Who Can Use Bis-Ethoxydiglycol Succinate

Because it is lightweight, non greasy and non pore clogging, Bis-Ethoxydiglycol Succinate tends to suit most skin types including oily, dry, combination and sensitive skin. People with highly compromised or broken skin barriers should still introduce any new product slowly until they know how their skin will react.

The ingredient is made from plant sourced ethoxydiglycol and bio based succinic acid, so it is generally considered suitable for vegans and vegetarians as long as the finished product has not been tested on animals.

No evidence suggests that topical Bis-Ethoxydiglycol Succinate poses a risk during pregnancy or while breastfeeding. Absorption through intact skin is minimal, yet this is not medical advice and anyone who is pregnant or nursing should review all skincare choices with a qualified healthcare professional just to be safe.

The molecule does not increase photosensitivity and can be used day or night without extra sun precautions beyond a normal broad spectrum sunscreen.

Potential Side Effects/Adverse Reactions

Responses to topical Bis-Ethoxydiglycol Succinate vary from person to person. The points below outline potential side effects although most users experience none when the ingredient is formulated and used properly.

  • Mild temporary stinging
  • Light redness or flushing in very sensitive skin
  • Rare allergic contact dermatitis presenting as itching or small bumps
  • Enhanced penetration of strong actives already in the formula which may amplify their own irritation potential

If any of these reactions occur stop using the product and consult a healthcare provider or dermatologist for guidance.

Comedogenic Rating

Rating: 0 out of 5. Bis-Ethoxydiglycol Succinate is a light, water compatible ester that leaves no greasy residue and does not form an occlusive film on the skin, so it has little to no tendency to block pores. Its small molecular size and quick absorption further reduce the risk of buildup inside follicles.

Suitable for acne-prone or breakout-prone skin.

Keep in mind overall formula matters; if the final product contains heavy oils or waxes the comedogenic potential can rise regardless of this single ingredient.

Summary

Bis-Ethoxydiglycol Succinate works as a humectant, skin conditioner and solvent. It pulls moisture into the upper skin layers, leaves a soft silky finish while avoiding heaviness and helps dissolve stubborn active ingredients so they stay evenly dispersed and stable in a formula.

Although not as famous as hyaluronic acid or propylene glycol it is gaining quiet popularity among formulators who want a lighter feel and better compatibility with both water and oil based actives.

Safety testing shows a low irritation and allergy profile making it generally safe for daily use. As with any new product, doing a small patch test first is a smart step to confirm personal tolerance.

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